scholarly journals Alcohol Alters Insulin-Like Growth Factor-1-Induced Transforming Growth Factor β1 Synthesis in the Medial Basal Hypothalamus of the Prepubertal Female Rat

2014 ◽  
Vol 38 (10) ◽  
pp. 2572-2578 ◽  
Author(s):  
Jill K. Hiney ◽  
Vinod K. Srivastava ◽  
Claire E. Volz ◽  
William L. Dees
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Female Rat ◽  
Insulin Like Growth Factor ◽  
Medial Basal Hypothalamus

Transforming growth factor β1, pituitary-specifi c transcriptional factor 1 and insulin-like growth factor I gene polymorphisms in the population of the Poltava clay chicken breed: association with productive traits

2015 ◽  
Vol 2 (1) ◽  
pp. 67-72
Author(s):  
R. Kulibaba ◽  
A. Tereshchenko
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Transcriptional Factor ◽  
Meat Production ◽  
Insulin Like Growth Factor ◽  
Chicken Breed ◽  
Igf I ◽  
Productive Traits ◽  
Tgf Β1

Aim. To investigate the gene polymorphisms of transforming growth factor β1 (TGF-β1), pituitary-specifi c transcriptional factor 1 (PIT-1) and insulin-like growth factor I (IGF-I) in the population of Poltava clay chicken breed, used for egg and meat production, and to analyze the association of different genotypes for each locus with productive traits. Methods. Genotyping of the chickens was performed using the polymerase chain reaction – restriction fragment length polymorphism (PCR-RFLP). Results. Transforming growth factor TGF-β1, pituitary-specifi c transcriptional factor PIT-1, and insulin-like growth factor IGF-I were shown to be polymorphic in the studied populations. The association between genotypes by the loci TGF-β1 and PIT-1 and the indices of egg and meat production of chickens was demonstrated. Conclusions. The data on the genetic structure of the population of Poltava clay chicken breed by loci TGF-β1 and PIT-1 is recommended for the targeted selection of chickens to produce offspring with desirable genotypes, which will, in addition to classical breeding methods, reveal the productive potential of chickens as effi ciently as possible.

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