A blinded randomised study comparing intubating conditions after either rocuronium 0.6 mg kg ‐1 or remifentanil 2 µg kg ‐1 in elderly patients

2021 ◽  
Author(s):  
Matias Vested ◽  
Anne Marie Sørensen ◽  
Cecilie Bjerring ◽  
Rasmus Ejlersgård Christensen ◽  
Felicia Dinesen ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Randomised Study ◽  
Intubating Conditions

Pressure ulcers prevention efficacy of an alternating pressure air mattress in elderly patients: E²MAO a randomised study

2017 ◽  
Vol 26 (6) ◽  
pp. 304-312 ◽  
Author(s):  
P. Sauvage ◽  
M. Touflet ◽  
C. Pradere ◽  
F. Portalier ◽  
J-M. Michel ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Pressure Ulcers ◽  
Randomised Study ◽  
Mao A

scholarly journals Comparative Evaluation of Ropivacaine versus Levobupivacaine for Postoperative Epidural Analgesia in Geriatric Patients Posted for Orthopedic Surgeries

2020 ◽  
Vol 5 (1) ◽  
pp. 47-51
Author(s):  
Shilpi Misra ◽  
Furkan Akhtar Ansari
Keyword(s):  
Elderly Patients ◽  
Epidural Analgesia ◽  
Analgesic Effect ◽  
Motor Block ◽  
Geriatric Patients ◽  
Drug Induced ◽  
Continuous Epidural Infusion ◽  
Randomised Study ◽  
Group I ◽  
Daunting Task

Background: With increasing life expectancy, improved healthcare and increasing prosperity, the proportion of elderly population is increasing throughout the world. Post-operative pain management among elderly patients  is a challenging and daunting task for anaesthesiologists. Altered redistribution kinetics as well as compromised drug clearance capacity render geriatric patients particularly vulnerable to drug-induced complications. Regional anaesthesia is preferred for the older patients because this form of anaesthesia causes the least interference with the metabolic functions.Subjects and Methods:56 elderly patients  scheduled for elective orthopaedic lower limb surgery under epidural anaesthesia with continuous post-operative epidural analgesia were enrolled in this prospective randomised study and were randomly allocated to two groups  consisting 28 patients each as under: Group I : Epidural analgesia Ropivacaine 0.2% @ 6ml/hr. Group II: Epidural analgesia Levobupivacaine 0.2% @ 6ml/hr. Statistical evaluation: Hemodynamic profiles, Onset of analgesia, extent of sensory and motor block  were recorded.  To compare the change in a parameter at two different time intervals paired "t" test was used. Block characteristics were analysed using Mann Whitney U test.Results:Both Ropivacaine and levobupivacaine provided excellent analgesic effect, a good hemodynamic stability and complication free infusion. As compared to levobupivacaine, ropivacaine had an early motor block recovery, early achievement of VAS score 0, ability to achieve higher levels of block and finally prolongation of analgesic effect even after the infusion was stopped.Conclusion:As compared to levobupivacaine, ropivacaine seems to be a better option for continuous epidural infusion owing to early motor block recovery and prolonged analgesia   after the infusion was stopped.

Anastrozole compared to tamoxifen as primary endocrine therapy for early operable primary breast cancer in the elderly

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 11025-11025 ◽  
Author(s):  
M. Ying ◽  
A. Agrawal ◽  
L. Winterbottom ◽  
D. A. Morgan ◽  
I. O. Ellis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Elderly Patients ◽  
Endocrine Therapy ◽  
Aromatase Inhibitors ◽  
Primary Breast Cancer ◽  
The Elderly ◽  
Operable Breast Cancer ◽  
Primary Therapy ◽  
Randomised Study ◽  
Primary Endocrine Therapy

11025 Background: The optimal management of operable primary breast cancer in elderly is controversial. A high proportion of elderly patients refuse or are unfit for surgery. However the majority have oestrogen receptor positive (ER+) cancer and respond extremely well to endocrine therapy. The use of tamoxifen as primary therapy is well established but its efficacy has not been compared with the newer aromatase inhibitors in this setting. We present the clinical data of the use of anastrozole when compared with tamoxifen in elderly patients as primary therapy for operable breast cancer. Methods: During a period of 2 years, elderly patients with ER+ operable breast cancer (<5cm), who either refused or were unfit for surgery, were given primary endocrine therapy. Tamoxifen was given by default but anastrozole was used when there were contraindications (eg thromboembolic and gynaecological risks). All had disease assessable to UICC criteria and were followed up in a dedicated clinic. Only patients who had treatment for =6 months (except for those who progressed prior) were included for analysis. Results: A total of 93 patients fulfilled the criteria for analysis thus far and the results are summarised as follows: 58 were given anastrozole and 35 with tamoxifen. At a median follow-up of 14.8 months (6 to 57), 8 patients have progressed. The results are summarised as follows: CR = complete response PR= partial response SD = stable disease Treatment was well tolerated in both groups and no patients withdrew due to side effects. Conclusions: The use of primary endocrine therapy in ER+ operable breast cancer in the elderly is highly effective. In this observational non randomised study there was no difference in efficacy detected between tamoxifen and anastrozole at this time, as seen in adjuvant trials. This may be due to the fact that majority of ER+ cancer in the elderly are highly ER rich as shown by high semi-quantitative scoring of immunhistological assays, making the superiority of the aromatase inhibitors less apparent. [Table: see text] No significant financial relationships to disclose.

scholarly journals P01.072 Hydroxychloroquine and short course radiotherapy for elderly patients with glioma: a randomised study

2018 ◽  
Vol 20 (suppl_3) ◽  
pp. iii246-iii246
Author(s):  
L Brazil ◽  
A Swampillai ◽  
K Mak ◽  
A Hackshaw ◽  
D Edwards ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Randomised Study ◽  
Short Course ◽  
Short Course Radiotherapy
Sign in / Sign up

Export Citation Format

Share Document