The Cuff Leak Test In Critically Ill Patients: An International Survey of Intensivists

Author(s):  
Kimberley Lewis ◽  
Yousef Almubarak ◽  
Morten Hylander Møller ◽  
Roman Jaeschke ◽  
Dan Perri ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Aiko Tanaka ◽  
Akinori Uchiyama ◽  
Yu Horiguchi ◽  
Ryota Higeno ◽  
Ryota Sakaguchi ◽  
...  

AbstractThe cuff leak test (CLT) has been widely accepted as a simple and noninvasive method for predicting post-extubation stridor (PES). However, its accuracy and clinical impact remain uncertain. We aimed to evaluate the reliability of CLT and to assess the impact of pre-extubation variables on the incidence of PES. A prospective observational study was performed on adult critically ill patients who required mechanical ventilation for more than 24 h. Patients were extubated after the successful spontaneous breathing trial, and CLT was conducted before extubation. Of the 191 patients studied, 26 (13.6%) were deemed positive through CLT. PES developed in 19 patients (9.9%) and resulted in a higher reintubation rate (8.1% vs. 52.6%, p < 0.001) and longer intensive care unit stay (8 [4.5–14] vs. 12 [8–30.5] days, p = 0.01) than patients without PES. The incidence of PES and post-extubation outcomes were similar in patients with both positive and negative CLT results. Compared with patients without PES, patients with PES had longer durations of endotracheal intubation and required endotracheal suctioning more frequently during the 24-h period prior to extubation. After adjusting for confounding factors, frequent endotracheal suctioning more than 15 times per day was associated with an adjusted odds ratio of 2.97 (95% confidence interval, 1.01–8.77) for PES. In conclusion, frequent endotracheal suctioning before extubation was a significant PES predictor in critically ill patients. Further investigations of its impact on the incidence of PES and patient outcomes are warranted.


2017 ◽  
Vol 34 (5) ◽  
pp. 391-396 ◽  
Author(s):  
David Schnell ◽  
Benjamin Planquette ◽  
Asaël Berger ◽  
Sybille Merceron ◽  
Julien Mayaux ◽  
...  

Background: Cuff leak test was developed to predict the occurrence of post-extubation stridor (PES). This study evaluated the diagnostic performance of this test in unselected critically ill patients. Methods: Multicenter prospective study including unselected ventilated patients at the time of their first planned extubation. The diagnostic performance of 4 different cuff leak tests was assessed. Results: Post-extubation stridor occurred in 34 (9.4%) of 362 included patients. Compared to patients without PES, patients with PES required more frequently reintubation (6 [17.6%] vs 26 [7.9%], P = .041), prolonged duration of ventilation (6 [3-13] vs 5 [2-9] days, P = .029), and longer intensive care unit (ICU) stay (12 [6-17.5] vs 7.5 [4-13] days, P = .018). However, ICU mortality was similar in both groups (1 [2.9%] vs 23 [7.0%], P = .61). The 4 cuff leak tests display poor diagnostic accuracy: sensitivities ranging from 27% to 46%, specificities from 70% to 88%, positive predictive values from 14% to 19%, and negative predictive values from 92% to 93%. Conclusion: Post-extubation stridor occurs in less than 10% of unselected critically ill patients. The several cuff leak tests display limited diagnostic performance for the detection of PES. Given the high rate of false positives, routine cuff leak test may expose to undue prolonged mechanical ventilation.


2020 ◽  
Vol 21 (9) ◽  
pp. e696-e706 ◽  
Author(s):  
Kim C. Noël ◽  
Jesse Papenburg ◽  
Jacques Lacroix ◽  
Caroline Quach ◽  
Shauna O’Donnell ◽  
...  

2010 ◽  
Vol 30 (3) ◽  
pp. 214-220 ◽  
Author(s):  
Flavio Basso ◽  
Zaccaria Ricci ◽  
Dinna Cruz ◽  
Claudio Ronco

2004 ◽  
Vol 30 (12) ◽  
pp. 2222-2229 ◽  
Author(s):  
Fr�d�rique Schortgen ◽  
Nicolas Deye ◽  
Laurent Brochard ◽  

2001 ◽  
Vol 16 (2) ◽  
pp. 230-237 ◽  
Author(s):  
Claudio Ronco ◽  
Monica Zanella ◽  
Alessandra Brendolan ◽  
Massimo Milan ◽  
Giovanna Canato ◽  
...  

Critical Care ◽  
2012 ◽  
Vol 16 (S1) ◽  
Author(s):  
F Lamontagne ◽  
N Adhikari ◽  
D Cook ◽  
KK Koo ◽  
F Lauzier ◽  
...  

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