scholarly journals Iatrogenic withdrawal syndrome frequently occurs in paediatric intensive care without algorithm for tapering of analgosedation

2021 ◽  
Author(s):  
Mette Dokken ◽  
Tone Rustøen ◽  
Lien My Diep ◽  
Frode Even Fagermoen ◽  
Rakel Iren Huse ◽  
...  
Keyword(s):  
Intensive Care ◽  
Withdrawal Syndrome ◽  
Paediatric Intensive Care ◽  
Iatrogenic Withdrawal Syndrome

High doses of benzodiazepine predict analgesic and sedative drug withdrawal syndrome in paediatric intensive care patients

2014 ◽  
Vol 103 (12) ◽  
pp. e538-e543 ◽  
Author(s):  
A Amigoni ◽  
E Vettore ◽  
V Brugnolaro ◽  
L Brugnaro ◽  
D Gaffo ◽  
...  
Keyword(s):  
Intensive Care ◽  
Withdrawal Syndrome ◽  
Drug Withdrawal ◽  
Paediatric Intensive Care ◽  
Sedative Drug ◽  
Intensive Care Patients ◽  
High Doses

scholarly journals Dexmedetomidine and Iatrogenic Withdrawal Syndrome in Critically Ill Children

2021 ◽  
Vol 41 (1) ◽  
pp. e17-e23
Author(s):  
Barbara M. Geven ◽  
Jolanda M. Maaskant ◽  
Catherine S. Ward ◽  
Job B.M. van Woensel
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Cumulative Dose ◽  
Withdrawal Syndrome ◽  
Significant Risk ◽  
Pediatric Intensive Care ◽  
Significant Risk Factor ◽  
Preventive Effect ◽  
Iatrogenic Withdrawal Syndrome

Background Iatrogenic withdrawal syndrome is a well-known adverse effect of sedatives and analgesics commonly used in patients receiving mechanical ventilation in the pediatric intensive care unit, with an incidence of up to 64.6%. When standard sedative and analgesic treatment is inadequate, dexmedetomidine may be added. The effect of supplemental dexmedetomidine on iatrogenic withdrawal syndrome is unclear. Objective To explore the potentially preventive effect of dexmedetomidine, used as a supplement to standard morphine and midazolam regimens, on the development of iatrogenic withdrawal syndrome in patients receiving mechanical ventilation in the pediatric intensive care unit. Methods This retrospective observational study used data from patients on a 10-bed general pediatric intensive care unit. Iatrogenic withdrawal syndrome was measured using the Sophia Observation withdrawal Symptoms-scale. Results In a sample of 102 patients, the cumulative dose of dexmedetomidine had no preventive effect on the development of iatrogenic withdrawal syndrome (P = .19). After correction for the imbalance in the baseline characteristics between patients who did and did not receive dexmedetomidine, the cumulative dose of midazolam was found to be a significant risk factor for iatrogenic withdrawal syndrome (P < .03). Conclusion In this study, supplemental dexmedetomidine had no preventive effect on iatrogenic withdrawal syndrome in patients receiving sedative treatment in the pediatric intensive care unit. The cumulative dose of midazolam was a significant risk factor for iatrogenic withdrawal syndrome.

scholarly journals Iatrogenic withdrawal syndrome in the pediatric cardiac intensive care unit: Incidence, risk factors and outcome

2021 ◽  
Vol 33 (4) ◽  
pp. 251-260
Author(s):  
Eiad Habib ◽  
Abdul Hakim Almakadma ◽  
Mohieddin Albarazi ◽  
Somiya Jaimon ◽  
Rayd Almehizia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Withdrawal Syndrome ◽  
Cardiac Intensive Care Unit ◽  
Incidence Risk ◽  
Cardiac Intensive Care ◽  
Iatrogenic Withdrawal Syndrome

scholarly journals Assessment and treatment of the withdrawal syndrome in paediatric intensive care units

Medicine ◽  
2020 ◽  
Vol 99 (5) ◽  
pp. e18502 ◽  
Author(s):  
Jennihe Alejandra Ávila-Alzate ◽  
Juan Gómez-Salgado ◽  
Macarena Romero-Martín ◽  
Santiago Martínez-Isasi ◽  
Yolanda Navarro-Abal ◽  
...  
Keyword(s):  
Intensive Care ◽  
Intensive Care Units ◽  
Withdrawal Syndrome ◽  
Paediatric Intensive Care ◽  
Assessment And Treatment ◽  
Paediatric Intensive Care Units

scholarly journals Opioid and Benzodiazepine Iatrogenic Withdrawal Syndrome in Patients in the Intensive Care Unit

2019 ◽  
Vol 30 (4) ◽  
pp. 353-364
Author(s):  
Carmen Mabel Arroyo-Novoa ◽  
Milagros I. Figueroa-Ramos ◽  
Kathleen A. Puntillo
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
At Risk ◽  
Intensive Care ◽  
Intensive Care Unit Stay ◽  
Withdrawal Syndrome ◽  
Adult Patients ◽  
Negative Outcomes ◽  
Patients At Risk ◽  
Iatrogenic Withdrawal Syndrome

Iatrogenic withdrawal syndrome is an increasingly recognized issue among adult patients in the intensive care unit. The prolonged use of opioids and benzodiazepines during the intensive care unit stay and preexisting disorders associated with their use put patients at risk of developing iatrogenic withdrawal syndrome. Although research to date is scant regarding iatrogenic withdrawal syndrome in adult patients in the intensive care unit, it is important to recognize and adequately manage iatrogenic withdrawal syndrome in order to prevent possible negative outcomes during and after a patient’s intensive care unit stay. This article discusses in depth 8 studies of iatrogenic withdrawal syndrome among adult patients in the intensive care unit. It also addresses important aspects of opioid and benzodiazepine iatrogenic withdrawal syndrome, including prevalence, risk factors, and assessment and considers its prevention and management.

Essentials of paediatric intensive care

2005 ◽  
Vol 94 (6) ◽  
pp. 814-814
Author(s):  
Bjorn Larsson
Keyword(s):  
Intensive Care ◽  
Paediatric Intensive Care
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