Continuous intravenous infusion of enoxaparin controls thrombin formation more than standard subcutaneous administration in critically ill patients. A sub‐study of the ENOKSI thromboprophylaxis RCT

2020 ◽  
Vol 65 (1) ◽  
pp. 109-115
Author(s):  
Annukka Vahtera ◽  
Timea Szanto ◽  
Riitta Lassila ◽  
Miia Valkonen ◽  
Mirka Sivula ◽  
...  
CHEST Journal ◽  
2006 ◽  
Vol 130 (4) ◽  
pp. 149S
Author(s):  
Rick Carlson ◽  
James F. Orme ◽  
Samuel Abatte ◽  
Margaret Baldwin ◽  
Joylyn Call ◽  
...  

2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S155-S155
Author(s):  
Frédéric Frippiat ◽  
Laurence Seidel ◽  
Raphael Denooz ◽  
Pierre Damas ◽  
Nathalie Layios ◽  
...  

PEDIATRICS ◽  
1957 ◽  
Vol 19 (2) ◽  
pp. 342-343
Author(s):  
DAVID B. SHURTLEFF

Clinical and metabolic studies have PEDIATRIC I.V. DRIP [SEE FIG I. IN SOURCE PDF] indicated that critically ill patients may lose temporarily a major portion of their usual tolerance for water and certain electrolytes (New England J. Med., 252:856, 1955). As a result, they are apt to become water-intoxicated if given too much solute-free water and salt-intoxicated if given too much saline, especially during the operative and immediate postoperative periods. It would appear that one simple way to avoid these difficulties is to keep the rate of intravenous fluid administration down to approximately 1200 ml/m2 of body surface area per 24 hours during such critical periods. In the adult of 1.8 m2 (70 kg), this rate of administration would mean the delivery of an absolute total of about 2200 ml/day.


1979 ◽  
Vol 7 (2) ◽  
pp. 143-147 ◽  
Author(s):  
J. F. Cade ◽  
M. C. F. Pain

Superinfections with resistant micro-organisms have recently become an increasing problem in hospital patients and are thought to be contributed to by inappropriate use of newer, broad-spectrum antibiotics. Erythromycin exhibits a more limited spectrum of antibacterial activity and was therefore re-evaluated in the treatment of acute chest infections in critically ill patients. Twenty-one patients were given erythromycin in a dose of 1.8 g per day by continuous intravenous infusion for up to five days. A satisfactory clinical response occurred in ten patients, in all of whom erythromycin-sensitive micro-organisms were isolated from sputum. An unsatisfactory response occurred in six patients, all associated with micro-organisms insensitive to erythromycin and requiring alternative antibiotic treatment. No undesirable side-effects were noted. It is concluded that erythromycin is a safe and useful agent in the routine treatment of acute chest infections in critically ill patients.


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