scholarly journals Venous thromboembolism in the critically ill: A prospective observational study of occurrence, risk factors and outcome

2019 ◽  
Vol 63 (5) ◽  
pp. 630-638 ◽  
Author(s):  
Sigrid Beitland ◽  
Henning Wimmer ◽  
Torleif Lorentsen ◽  
Dag Jacobsen ◽  
Tomas Drægni ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Observational Study ◽  
Critically Ill ◽  
Prospective Observational Study

scholarly journals Risk factors for chemotherapy-associated venous thromboembolism in a prospective observational study

Cancer ◽  
2005 ◽  
Vol 104 (12) ◽  
pp. 2822-2829 ◽  
Author(s):  
Alok A. Khorana ◽  
Charles W. Francis ◽  
Eva Culakova ◽  
Gary H. Lyman
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Observational Study ◽  
Prospective Observational Study

scholarly journals The Incidence and Characteristics of Venous Thromboembolism in Neurocritical Care Patients: A Prospective Observational Study

2020 ◽  
Vol 26 ◽  
pp. 107602962090795
Author(s):  
Ping Zhang ◽  
Yi Bian ◽  
Feng Xu ◽  
Lifei Lian ◽  
Suiqiang Zhu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Pulmonary Infection ◽  
Neurocritical Care ◽  
Femoral Vein ◽  
Pulmonary Arteries ◽  
Vein Thrombosis ◽  
Independent Risk Factors

Risk of venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is presumed to be high for neurologic intensive care unit (NICU) patients. However, exact incidences of VTE have yet to be reported. In this prospective observational study, we consecutively enrolled 126 neurocritical care patients who had an NICU stay ≥1 week with paralysis and/or unconsciousness. All patients received DVT prevention strategies. Patients were screened for VTE after 1 week of hospitalization, using venous ultrasonography and computed tomography pulmonary angiography. Following 1 week of NICU hospitalization, DVT incidence was 35.7% and PE incidence was 17.5%. Of the DVTs, 75.6% were in the muscular calf vein. Of the PEs, 22.7% were in main pulmonary arteries, while 77.3% were in branches. Approximately 96% of the DVTs and 86% of the PEs were asymptomatic. Approximately 24% of patients with DVT had a concurrent PE, while 50% of PE patients had a DVT. Paralysis, raised d-dimer on admission, and pulmonary infection were found to be independent risk factors for DVT. Paraplegia, femoral vein thrombosis, and pulmonary infection were found to be independent risk factors for PE. Despite active preventive measures, incidences of VTE in NICU patients were high. Most VTEs were asymptomatic, meaning they could have led to a missed diagnosis. Attention should be paid to the VTE events of critically ill neurological patients.

1451 PROSPECTIVE OBSERVATIONAL STUDY OF VENOUS THROMBOEMBOLISM RISK OF PATIENTS UNDERGOING PARTIAL AND RADICAL NEPHRECTOMY

2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
Jessica T. Casey ◽  
Gregory B. Auffenberg ◽  
Laura Mazzenga ◽  
Theresa Sweeney ◽  
Michael A. Dixon ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Observational Study ◽  
Radical Nephrectomy ◽  
Prospective Observational Study

scholarly journals POS0441 DEVELOPMENT OF RHEUMATOID ARTHRITIS AMONG ANTI-CITRULLINATED PROTEIN ANTIBODIES POSITIVE ASYMPTOMATIC INDIVIDUALS: A PROSPECTIVE OBSERVATIONAL STUDY

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 449.1-449
Author(s):  
S. Mizuki ◽  
K. Horie ◽  
K. Imabayashi ◽  
K. Mishima ◽  
K. Oryoji
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Observational Study ◽  
Rheumatoid Factor ◽  
Prospective Observational Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
P Value ◽  
Healthy Population ◽  
Asymptomatic Individuals ◽  
Citrullinated Protein

Background:In the idividuals with genetic and enviromental risk factors, immune events at mucosal surfaces occur and may precede systemic autoimmunity. Anti-citrullinated protein antibodies (ACPA) are present in the serum for an average of 3-5 years prior to the onset of rheumatoid arthritis (RA) during an asymptomatic period. In ACPA-positivite individuals, the additional presence of RA-related risk factors appears to add significant power for the development of RA. To date, there have been few reports in which clinical courses of ACPA-positive asymptomatic individuals were investigated prospectively.Objectives:To observe the clinical time course of ACPA-positive healthy population for the development of RA.Methods:Healthy volunteers without joint pain or stiffness, who attended the comprehensive health screening of our hospital, were enrolled in this prospective observational study. The serum ACPA levels were quantified by Ig-G anti-cyclic citrullinated peptide enzyme-linked immunosorbent assay with levels > 4.4 U/mL considered positive. ACPA-positive subjects were followed by rheumatologists of our department clinically or a questionnaire sent by mail for screening to detect arthritis.Results:5,971 healthy individuals without joint symptons were included. Ninty-two (1.5%) were positive for ACPA. Of these, 19 (20.7%) developed RA and two were suspected as RA by mail questionnaire. Their average age were 58-years, and women were 68%. The average duration between the date of serum sampling and diagnosis was 10.7 months. ACPA-positive individuals who developed to RA had higher serum ACPA and Ig-M rheumatoid factor levels than ACPA-positive individuals who did not (P value by Mann-Whitney U test: 0.002, 0.005, respectively).Conclusion:Among ACPA-positive asymptomatic individuals, 20% developed RA. The higher titer of ACPA and Ig-M rheumatoid factor levels are risk factors for devoloping RA.Disclosure of Interests:None declared

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