THAM administration reduces pulmonary carbon dioxide elimination in hypercapnia - an experimental porcine study

2018 ◽  
Vol 62 (6) ◽  
pp. 820-828
Author(s):  
S. Höstman ◽  
R. Kawati ◽  
G. Perchiazzi ◽  
A. Larsson
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Elimination

Carbon dioxide elimination during circulatory arrest

1987 ◽  
Vol 15 (10) ◽  
pp. 944-946 ◽  
Author(s):  
SHUJI DOHI ◽  
REIKO TAKESHIMA ◽  
NAOKI MATSUMIYA
Keyword(s):  
Carbon Dioxide ◽  
Circulatory Arrest ◽  
Carbon Dioxide Elimination

Inhibition of carbonic anhydrase: its effect on carbon dioxide elimination by the lungs

1959 ◽  
Vol 14 (1) ◽  
pp. 109-115 ◽  
Author(s):  
John C. Mithoefer
Keyword(s):  
Carbon Dioxide ◽  
Steady State ◽  
Carbonic Anhydrase ◽  
Normal Animal ◽  
Carbon Dioxide Elimination ◽  
Carbonic Anhydrase Inhibition ◽  
Experimental Approaches

The effect of carbonic anhydrase inhibition on carbon dioxide elimination by the lungs has been studied in dogs by the following four experimental approaches: 1) the alveolar pathway (PaOO2 and PaCOCO2) was measured during the hyperventilation which follows carbonic anhydrase inhibition and compared to the normal pathway at the same hyperventilation. 2) The alveolar gas tensions were measured following carbonic anhydrase inhibition when the ventilation was held constant. 3) The changes in PaCOCO2 were measured when the ventilation was suddenly, artificially changed to a new level in the presence of carbonic anhydrase inhibition and in normal animals. 4) The CO2 output was measured directly during the hyperventilation which results from carbonic anhydrase inhibition, during the same hyperventilation in the normal animal and following carbonic anhydrase inhibition when the ventilation is held constant. These experiments demonstrate an immediate fall in CO2 output relative to the ventilation when carbonic anhydrase is inhibited, resulting in CO2 retention until a new steady state has been reached. An hypothesis is presented to explain the effect of carbonic anhydrase inhibition on CO2 transport. Submitted on March 28, 1958

Hemodynamic response of normal men to graded treadmill exercise

1964 ◽  
Vol 19 (3) ◽  
pp. 457-464 ◽  
Author(s):  
Burton S. Tabakin ◽  
John S. Hanson ◽  
Thornton W. Merriam ◽  
Edgar J. Caldwell
Keyword(s):  
Carbon Dioxide ◽  
Heart Rate ◽  
Cardiac Output ◽  
Arterial Pressure ◽  
Stroke Volume ◽  
Treadmill Exercise ◽  
Minute Volume ◽  
Peripheral Vascular ◽  
Carbon Dioxide Elimination ◽  
Oxygen Utilization

The physiologic variables defining the circulatory and respiratory state in normal man have been measured in recumbency, standing at rest and during progressively severe grades of exercise approaching near-maximal levels. Indicator-dilution technique was used for determination of cardiac output with simultaneous radio-electrocardiographic recordings of heart rate. Direct intra-arterial pressure measurements were utilized for calculation of peripheral vascular resistance. Minute volume of ventilation, oxygen utilization, and carbon dioxide elimination were obtained from analysis of expired air collected at the time of each cardiac output determination. A peak mean workload of 1,501 kg-m/min was realized during the treadmill exercise. Increases in cardiac output over the range of exercise employed correlated well with indices of workload such as heart rate, oxygen utilization, and minute volume of ventilation. There was no correlation of stroke volume with these indices. It is concluded from examination of individual stroke-volume responses that a progressive increase in stroke volume is not a necessary or constant phenomenon in adapting to increasing workload. cardiac output in treadmill exercise; dye-dilution cardiac output determinations; arterial pressure during upright exercise; stroke-volume response to graded treadmill exercise; exercise response of cardiac output and stroke volume; peripheral vascular resistance response to position and exercise; treadmill exercise—effects on cardiac output, stroke volume, and oxygen uptake; minute ventilation, cardiac output, and stroke volume during exercise; carbon dioxide elimination during treadmill exercise; heart rate and cardiac output during treadmill exercise; exercise; physiology Submitted on July 12, 1963

Energy metabolism in hypnotic trance and sleep

1965 ◽  
Vol 20 (2) ◽  
pp. 308-310 ◽  
Author(s):  
Hrishikesh Jana
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Energy Metabolism ◽  
Respiratory Quotient ◽  
Metabolic Rates ◽  
Carbon Dioxide Elimination ◽  
Natural Sleep ◽  
Healthy Males

The energy metabolism of 14 healthy males was studied before and during a hypnotic trance in the basal state. Metabolic rates during the basal waking, the basal hypnotic trance and the basal sleep were also determined in three subjects for 3 consecutive days, respectively. It was observed that a hypnotic trance does not significantly influence the metabolic rates in a basal condition while natural sleep lowers the basal metabolic rates by 8.73%. hypnosis; oxygen consumption; carbon dioxide; elimination; respiratory quotient Submitted on April 7, 1964

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