Low-intensity endurance exercise plus nandrolone decanoate modulates cardiac adiponectin and its receptors

2017 ◽  
Vol 37 (2) ◽  
pp. 29-33
Author(s):  
A. Karimi ◽  
S. Joukar ◽  
H. Najafipour ◽  
Y. Masoumi-Ardakani ◽  
B. Shahouzehi
Keyword(s):  
Endurance Exercise ◽  
Nandrolone Decanoate ◽  
Low Intensity

scholarly journals Effects over one year of low-intensity endurance exercise targeted at the level of maximal lipid oxidation

2015 ◽  
Vol 30 (5) ◽  
pp. e127-e131 ◽  
Author(s):  
M. Guiraudou ◽  
C. Fédou ◽  
A.-J. Romain ◽  
A. Sferlazza ◽  
E. Calas ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Endurance Exercise ◽  
Low Intensity ◽  
One Year

scholarly journals Low-Intensity Exercise Training Additionally Increases Mitochondrial Dynamics Caused by High-Fat Diet (HFD) but Has No Additional Effect on Mitochondrial Biogenesis in Fast-Twitch Muscle by HFD

2020 ◽  
Vol 17 (15) ◽  
pp. 5461
Author(s):  
Yun Seok Kang ◽  
Donghun Seong ◽  
Jae Cheol Kim ◽  
Sang Hyun Kim
Keyword(s):  
Endurance Exercise ◽  
Mitochondrial Biogenesis ◽  
High Fat Diet ◽  
Mitochondrial Dynamics ◽  
Chow Diet ◽  
Sprague Dawley ◽  
High Fat ◽  
Related Factors ◽  
Mitochondrial Dynamic ◽  
Low Intensity

This study examines how the high-fat diet (HFD) affects mitochondrial dynamics and biogenesis, and also whether combining it with low-intensity endurance exercise adds to these effects. Six 8-week-old male Sprague–Dawley (SD) rats were put on control (CON; standard chow diet), HF (HFD intake), and HFEx (HFD + low-intensity treadmill exercise) for 6 weeks. As a result, no change in body weight was observed among the groups. However, epididymal fat mass increased significantly in the two groups that had been given HFD. Blood free fatty acid (FFA) also increased significantly in the HF group. While HFD increased insulin resistance (IR), this was improved significantly in the HFEx group. HFD also significantly increased mitochondrial biogenesis-related factors (PPARδ, PGC-1α, and mtTFA) and mitochondrial electron transport chain proteins; however, no additional effect from exercise was observed. Mitochondrial dynamic-related factors were also affected: Mfn2 increased significantly in the HFEx group, while Drp1 and Fis-1 increased significantly in both the HF and HFEx groups. The number of mitochondria in the subsarcolemmal region, and their size in the subsarcolemmal and intermyofibrillar regions, also increased significantly in the HFEx group. Taken overall, these results show that HFD in combination with low-intensity endurance exercise has no additive effect on mitochondrial biogenesis, although it does have such an effect on mitochondrial dynamics by improving IR.

scholarly journals Erratum to: The Effects of Nandrolone Decanoate Along with Prolonged Low-Intensity Exercise on Susceptibility to Ventricular Arrhythmias

2015 ◽  
Vol 15 (3) ◽  
pp. 290-290 ◽  
Author(s):  
Fateme Binayi ◽  
Siyavash Joukar ◽  
Hamid Najafipour ◽  
Abdolah Karimi ◽  
Farzane Abdollahi ◽  
...  
Keyword(s):  
Ventricular Arrhythmias ◽  
Nandrolone Decanoate ◽  
Low Intensity ◽  
Low Intensity Exercise

scholarly journals Reduction in mdx mouse muscle degeneration by low-intensity endurance exercise: a proteomic analysis in quadriceps muscle of exercised compared with sedentary mdx mice

2015 ◽  
Vol 35 (3) ◽  
Author(s):  
Simona Fontana ◽  
Odessa Schillaci ◽  
Monica Frinchi ◽  
Marco Giallombardo ◽  
Giuseppe Morici ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Endurance Exercise ◽  
Proteomic Analysis ◽  
Quadriceps Muscle ◽  
Mdx Mouse ◽  
Mdx Mice ◽  
Muscle Degeneration ◽  
Wild Type ◽  
Mouse Muscle ◽  
Low Intensity

By proteomic analysis we found an up-regulation of four carbonic anhydrase-3 (CA3) isoforms and a down-regulation of superoxide dismutase [Cu-Zn] (SODC) in quadriceps of sedentary X-linked muscular dystrophy (mdx) mice as compared with wild–type (WT) mice and the levels were significantly restored to WT values following low-intensity endurance exercise.

scholarly journals The risk of life-threatening ventricular arrhythmias in presence of high-intensity endurance exercise along with chronic administration of nandrolone decanoate

Steroids ◽  
2016 ◽  
Vol 105 ◽  
pp. 106-112 ◽  
Author(s):  
Farzane Abdollahi ◽  
Siyavash Joukar ◽  
Hamid Najafipour ◽  
Abdolah Karimi ◽  
Yaser Masumi ◽  
...  
Keyword(s):  
Endurance Exercise ◽  
High Intensity ◽  
Ventricular Arrhythmias ◽  
Chronic Administration ◽  
Nandrolone Decanoate ◽  
Life Threatening

Ameliorative Effects of Endurance Exercise with Two Different Intensities on Nandrolone Decanoate-Induced Neurodegeneration in Rats: Involving Redox and Apoptotic Systems

2017 ◽  
Vol 32 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Siyavash Joukar ◽  
Reza Vahidi ◽  
Alireza Farsinejad ◽  
Majid Asadi-shekaari ◽  
Beydolah Shahouzehi
Keyword(s):  
Endurance Exercise ◽  
Nandrolone Decanoate

The Effects of Nandrolone Decanoate Along with Prolonged Low-Intensity Exercise on Susceptibility to Ventricular Arrhythmias

2015 ◽  
Vol 16 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Fateme Binayi ◽  
Siyavash Joukar ◽  
Hamid Najafipour ◽  
Ali Karimi ◽  
Farzane Abdollahi ◽  
...  
Keyword(s):  
Ventricular Arrhythmias ◽  
Nandrolone Decanoate ◽  
Low Intensity ◽  
Low Intensity Exercise

scholarly journals Effects of Long-Term Endurance Exercise and Lithium Treatment on Neuroprotective Factors in Hippocampus of Obese Rats

2020 ◽  
Vol 17 (9) ◽  
pp. 3317
Author(s):  
Jusik Park ◽  
Wookwang Cheon ◽  
Kijin Kim
Keyword(s):  
Endurance Exercise ◽  
Glycogen Synthase ◽  
Lithium Treatment ◽  
The Other ◽  
Control Group ◽  
Additive Effects ◽  
Bdnf Expression ◽  
Low Intensity ◽  
Obese Rats

To investigate the effects of long-term lithium treatment and low intensity endurance exercise on brain-derived neurotrophic factor (BDNF) expression and glycogen synthase kinase 3 beta (GSK3β) activity in the hippocampus of obese rats. Fifty 10-week-old male Sprague-Dawley rats were selected. There was a control group of 10 rats (chow control group) while the other forty rats were fed on a high-fat diet for eight weeks to induce obesity. Rats were then assigned into four random groups. The rats were given 10 mg/kg lithium chloride (LiCl) dissolved in 1 mL sterile distilled water once a day, 5 times a week. The rats did 20 min of treadmill walking with an exercise intensity of 40% maximal oxygen uptake (VO2 max) (12 m/min, slope 0%). This was performed for 20 min a day, 3 days a week. Twelve weeks of lithium treatment or endurance exercise significantly reduced body weight and body fat mass in obese rats, without showing additive effects when the treatments were given in parallel or significant toxic responses in alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels in blood and kidney and liver tissues. BDNF expression in the hippocampus was significantly increased both in exercise and lithium groups with synergistic effects found in the group where both exercise and lithium treatments were given in parallel. On the other hand, the decrease in GSK3β activity was shown only in the lithium treatment group, without showing additive effects when the treatments were given in parallel. Lithium and low-intensity endurance exercise for 12 weeks increased the expression of BDNF, a neuroprotective factor in the hippocampus of obese mice. Lithium treatment alone inhibited the activity of GSK3β. This can be interpreted as a positive indication of applicability of the two factors in the prevention of neurodegenerative diseases.

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