Intellectual software for analysis of histological images

Author(s):  
Alexander Nedzved ◽  
Valery Starovoitov
Author(s):  
Fernando Perez-Bueno ◽  
Miguel Vega ◽  
Valery Naranjo ◽  
Rafael Molina ◽  
Aggelos K. Katsaggelos

2021 ◽  
pp. 1-11
Author(s):  
Yaning Liu ◽  
Lin Han ◽  
Hexiang Wang ◽  
Bo Yin

Papillary thyroid carcinoma (PTC) is a common carcinoma in thyroid. As many benign thyroid nodules have the papillary structure which could easily be confused with PTC in morphology. Thus, pathologists have to take a lot of time on differential diagnosis of PTC besides personal diagnostic experience and there is no doubt that it is subjective and difficult to obtain consistency among observers. To address this issue, we applied deep learning to the differential diagnosis of PTC and proposed a histological image classification method for PTC based on the Inception Residual convolutional neural network (IRCNN) and support vector machine (SVM). First, in order to expand the dataset and solve the problem of histological image color inconsistency, a pre-processing module was constructed that included color transfer and mirror transform. Then, to alleviate overfitting of the deep learning model, we optimized the convolution neural network by combining Inception Network and Residual Network to extract image features. Finally, the SVM was trained via image features extracted by IRCNN to perform the classification task. Experimental results show effectiveness of the proposed method in the classification of PTC histological images.


Author(s):  
Elene Firmeza Ohata ◽  
João Victor Souza das Chagas ◽  
Gabriel Maia Bezerra ◽  
Mohammad Mehedi Hassan ◽  
Victor Hugo Costa de Albuquerque ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Chenchen Ren ◽  
Xianxu Zeng ◽  
Zhongna Shi ◽  
Chunyan Wang ◽  
Huifen Wang ◽  
...  

AbstractIn this prospective study of an in-vivo cervical examination using optical coherence tomography (OCT), we evaluated the diagnostic value of non-invasive and real-time OCT in cervical precancerous lesions and cancer diagnosis, and determined the characteristics of OCT images. 733 patients from 5 Chinese hospitals were inspected with OCT and colposcopy-directed biopsy. The OCT images were compared with the histological sections to find out the characteristics of various categories of lesions. The OCT images were also interpreted by 3 investigators to make a 2-class classification, and the results were compared against the pathological results. Various structures of the cervical tissue were clearly observed in OCT images, which matched well with the corresponding histological sections. The OCT diagnosis results delivered a sensitivity of 87.0% (95% confidence interval, CI 82.2–90.7%), a specificity of 84.1% (95% CI 80.3–87.2%), and an overall accuracy of 85.1%. Both good consistency of OCT images and histological images and satisfactory diagnosis results were provided by OCT. Due to its features of non-invasion, real-time, and accuracy, OCT is valuable for the in-vivo evaluation of cervical lesions and has the potential to be one of the routine cervical diagnosis methods.


2017 ◽  
Vol 81 ◽  
pp. 223-243 ◽  
Author(s):  
Thaína A. Azevedo Tosta ◽  
Paulo Rogério Faria ◽  
Leandro Alves Neves ◽  
Marcelo Zanchetta do Nascimento

2016 ◽  
Vol 35 (8) ◽  
pp. 1962-1971 ◽  
Author(s):  
Abhishek Vahadane ◽  
Tingying Peng ◽  
Amit Sethi ◽  
Shadi Albarqouni ◽  
Lichao Wang ◽  
...  

Author(s):  
Andrija Stajduhar ◽  
Claude Lepage ◽  
Milos Judas ◽  
Sven Loncaric ◽  
Alan C. Evans

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