scholarly journals Hybrid type-II ARQ/AMS supported by channel predictive scheduling in a multi-user scenario

Author(s):  
N.C. Ericsson ◽  
A. Ahlen ◽  
S. Falahati ◽  
A. Svensson
2020 ◽  
Vol 91 ◽  
pp. 105963 ◽  
Author(s):  
Kristie Long Foley ◽  
David P. Miller ◽  
Kathryn Weaver ◽  
Erin L. Sutfin ◽  
W. Jeffrey Petty ◽  
...  

2021 ◽  
Author(s):  
Keng-Yen Huang ◽  
Janet Nakigudde ◽  
Elizabeth Nsamba Kisakye ◽  
Hafsa Sentongo ◽  
Tracy A Dennis-Tiwary ◽  
...  

Abstract Background: There are numerous challenges to promoting child mental health in low-and-middle income countries (LMICs). Most evidence-based interventions (EBIs) adapted to LMICs have not been scaled widely or evaluated for effectiveness and underlying mechanisms. Most mental health EBIs in LMICs rely on a task-shifting approach of implementation because of the shortage of mental health professionals; however, challenges related to task-shifting are understudied. Most EBIs have not been implemented using a scalable and sustainable model that leverages and strengthens existing structures. Through a cross-sector collaboration, we are carrying out a second generation investigation of implementation and effectiveness of a school-based mental health EBI for early childhood students that uses task-shifting and builds on existing educational structures. The ultimate shared goal of this collaboration is to scale and sustain the EBI country wide. The systems-level approach to promoting child mental health builds on ParentCorps, an EBI implemented in schools that has been shown in multiple trials to yield long-term benefits on mental health and school performance. Previous studies in Uganda found that ParentCorps Professional Development (PD) for teachers resulted in short-term benefits for classrooms, children and families. Objectives: This paper describes the rationale and protocol for an effectiveness-implementation study of ParentCorps-PD for teachers in urban and rural Ugandan schools. The study considers the added value (i.e. impact and costs) of a brief wellness intervention for teachers in their task-shifting role and explores mechanisms and outcomes. Methods: Using a hybrid-type II effectiveness-implementation cluster randomized controlled trial (cRCT), we will randomize 36 schools (18 urban and 18 rural) with 540 teachers and nearly 2,000 families to one of three conditions: PD + Teacher-Wellness (PDT), PD alone (PD), and control. Primary effectiveness outcomes are teachers’ use of mental health promoting strategies, teacher stress management, and child mental health. Mixed methods will be employed to examine underlying mechanisms of implementation and impact as well as cost-effectiveness. Discussion: This research will generate important knowledge regarding the value of an EBI in urban and rural communities in a LMIC, and efforts toward supporting teachers who are task-shifting as a potentially cost-effective strategy for promoting child mental health. Trial Registration: This trial was registered with ClinicalTrials.gov (registration number: NCT04383327; https://clinicaltrials.gov/ct2/show/NCT04383327) on May13, 2020.


2021 ◽  
Author(s):  
Vincent Agyapong ◽  
Medard Adu ◽  
Reham Shalaby ◽  
Ejemai Eboreime ◽  
Adegboyega Sapara ◽  
...  

BACKGROUND Background: Major depressive disorder (MDD) accounts for 40.5% of disability-adjusted life-years caused by mental and substance use disorders. Barriers such as stigma and financial and physical access to care have been reported, highlighting the need for innovative, accessible, and cost-effective psychological interventions. The effectiveness of supportive SMS text messaging in alleviating depression symptoms has been proven in clinical trials, but this approach can only help those with mobile phones. OBJECTIVE Objective: This paper presents the protocol for a study that will aim to evaluate the feasibility, comparative effectiveness, and user satisfaction of daily supportive email messaging as an effective strategy compared to daily supportive text messaging as part of the treatment of patients with MDD. METHODS Methods: This trial will be carried out using a hybrid type II implementation-effectiveness design. This design evaluates the effectiveness of an implementation strategy or intervention, while also evaluating the implementation context associated with the intervention. Patients with MDD receiving usual care will be randomized to receive either daily supportive email messaging or daily supportive text messaging of the same content for 6 months. The Patient Health Questionnaire-9, the Generalized Anxiety Disorder-7 and the 5-item World Health Organization Well-Being Index will be used to evaluate the effectiveness of both strategies. The implementation evaluation will be guided by the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework, as well as the Consolidated Framework for Implementation Research. All outcome measures will be analyzed using descriptive and inferential statistics. Qualitative data will be analyzed using thematic analysis. RESULTS Results: Data collection for this trial began in April 2021. We expect the study results to be available within 18 months of study commencement. The results will shed light on the feasibility, acceptability, and effectiveness of using automated emails as a strategy for delivering supportive messages to patients with MDD in comparison to text messaging. CONCLUSIONS Conclusions: The outcome of this trial will have a translational impact on routine patient care and access to mental health, as well as potential support mental health policy decision-making for health care resource allocation CLINICALTRIAL Trial Registration: ClinicalTrials.gov NCT04638231; https://clinicaltrials.gov/ct2/show/NCT04638231 International Registered Report Identifier (IRRID): DERR1-10.2196/29495


PEDIATRICS ◽  
1978 ◽  
Vol 61 (2) ◽  
pp. 278-281
Author(s):  
Gladys H. Hirschman ◽  
James C. M. Chan

This report describes a case of subacute necrotizing encephalomyelopathy (Leigh's syndrome) in a 7-month-old boy. The clinical data suggest an association with a disorder of renal tubular acidification, characterized by both (proximal) type II and (distal) type I renal tubular acidosis (hybrid type). Concomitantly, the initial uncompensated metabolic acidosis evolved into a mixed metabolic acidosis and respiratory alkalosis-features of this syndrome not previously reported.


2017 ◽  
Vol 6 (1) ◽  
pp. 123-131 ◽  
Author(s):  
Mohamed A. W. Mahmoud ◽  
Rashad M. EL-Sagheer ◽  
Mahmoud M. M. Mansour

2020 ◽  
Vol 31 (4) ◽  
pp. 565-572
Author(s):  
Yanxiang Liu ◽  
Shenghua Liang ◽  
Bowen Zhang ◽  
Yunfeng Li ◽  
Lucheng Wang ◽  
...  

Abstract OBJECTIVES The aim was to evaluate the short-term outcomes of hybrid type II arch repair (HAR) and total arch replacement with frozen elephant trunk (TAR with FET) for acute DeBakey type I aortic dissection patients. METHODS From January 2017 to June 2019, the clinical data of acute DeBakey type I aortic dissection patients in a single centre were retrospectively reviewed; there were 92 cases of HAR and 268 cases of TAR with FET, with 56 pairs by propensity score matching. RESULTS After matching, the composite end points including 30-day mortality, stroke, paraplegia, renal failure, hepatic failure, reintubation or tracheotomy and low cardiac output syndrome were comparable (21.4%, 12/56 in the HAR group vs 21.4%, 12/56 in the TAR with FET group, P = 1.000). The rate of acute kidney injury (AKI) was significantly lower in the HAR group (58.9%, 33/56 vs 80.4%, 45/56, P = 0.031). The distribution of AKI stage according to the Kidney Disease Improving Global Outcomes criteria was different (P = 0.039), with more patients suffering from high-grade AKI in the TAR with FET group. Multivariable logistic analysis showed that the procedure type (HAR or TAR with FET) was not an independent predictor of composite adverse events or stroke. HAR was identified as a protective factor against AKI (odds ratio 0.485, 95% confidence interval 0.287–0.822; P = 0.007). CONCLUSIONS In the treatment of acute DeBakey type I aortic dissection, no significant differences were found in early outcomes between the 2 groups, but HAR was associated with a significantly lower incidence of AKI.


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