Ultrasound imaging from vaporization signals emitted by phase change contrast agents

2014 ◽  
Author(s):  
cChristopher B. Arena ◽  
cAnthony Novell ◽  
cPaul S. Sheeran ◽  
cConnor Puett ◽  
cLinsey C. Phillips ◽  
...  
Keyword(s):  
Phase Change ◽  
Contrast Agents ◽  
Ultrasound Imaging

scholarly journals Optically and acoustically triggerable sub-micron phase-change contrast agents for enhanced photoacoustic and ultrasound imaging

2017 ◽  
Vol 6 ◽  
pp. 26-36 ◽  
Author(s):  
Shengtao Lin ◽  
Anant Shah ◽  
Javier Hernández-Gil ◽  
Antonio Stanziola ◽  
Bethany I. Harriss ◽  
...  
Keyword(s):  
Phase Change ◽  
Contrast Agents ◽  
Ultrasound Imaging

scholarly journals From Micro- to Nano-Multifunctional Theranostic Platform: Effective Ultrasound Imaging Is Not Just a Matter of Scale

2018 ◽  
Vol 17 ◽  
pp. 153601211877821 ◽  
Author(s):  
Sara Zullino ◽  
Monica Argenziano ◽  
Ilaria Stura ◽  
Caterina Guiot ◽  
Roberta Cavalli
Keyword(s):  
Diagnostic Imaging ◽  
Phase Change ◽  
Contrast Agents ◽  
Ultrasound Imaging ◽  
Tumor Tissue ◽  
Ultrasound Contrast Agents ◽  
Acoustic Droplet Vaporization ◽  
Droplet Vaporization ◽  
Enhanced Permeability And Retention ◽  
Ultrasound Contrast

Ultrasound Contrast Agents (UCAs) consisting of gas-filled-coated Microbubbles (MBs) with diameters between 1 and 10 µm have been used for a number of decades in diagnostic imaging. In recent years, submicron contrast agents have proven to be a viable alternative to MBs for ultrasound (US)-based applications for their capability to extravasate and accumulate in the tumor tissue via the enhanced permeability and retention effect. After a short overview of the more recent approaches to ultrasound-mediated imaging and therapeutics at the nanoscale, phase-change contrast agents (PCCAs), which can be phase-transitioned into highly echogenic MBs by means of US, are here presented. The phenomenon of acoustic droplet vaporization (ADV) to produce bubbles is widely investigated for both imaging and therapeutic applications to develop promising theranostic platforms.

High frame rate ultrasound imaging of vaporised phase change contrast agents

2017 ◽  
Author(s):  
Shengtao Lin ◽  
Ge Zhang ◽  
Akaki Jamburidze ◽  
Melisse Chee ◽  
Chee Hau Leow ◽  
...  
Keyword(s):  
Phase Change ◽  
Contrast Agents ◽  
Ultrasound Imaging ◽  
Frame Rate ◽  
High Frame Rate

scholarly journals On-chip preparation of nanoscale contrast agents towards high-resolution ultrasound imaging

Lab on a Chip ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. 679-687 ◽  
Author(s):  
Sally A. Peyman ◽  
James R. McLaughlan ◽  
Radwa H. Abou-Saleh ◽  
Gemma Marston ◽  
Benjamin R. G. Johnson ◽  
...  
Keyword(s):  
High Resolution ◽  
Phase Change ◽  
Contrast Agents ◽  
Ultrasound Imaging ◽  
Diagnostic Ultrasound ◽  
Contrast Imaging ◽  
High Concentrations ◽  
On Chip

We present the first on-chip atomisation-like production of phase-change contrast agents at high concentrations towards high-resolution contrast imaging for diagnostic ultrasound.

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