scholarly journals On the use of dual acoustic radiation forces to induce shear wave propagation and interference pattern formation

Author(s):  
Kenneth Hoyt ◽  
Zaegyoo Hah ◽  
Chris Hazard ◽  
Kevin J Parker
2021 ◽  
Vol 9 ◽  
Author(s):  
Hongliang Li ◽  
Guillaume Flé ◽  
Manish Bhatt ◽  
Zhen Qu ◽  
Sajad Ghazavi ◽  
...  

Changes in biomechanical properties of biological soft tissues are often associated with physiological dysfunctions. Since biological soft tissues are hydrated, viscoelasticity is likely suitable to represent its solid-like behavior using elasticity and fluid-like behavior using viscosity. Shear wave elastography is a non-invasive imaging technology invented for clinical applications that has shown promise to characterize various tissue viscoelasticity. It is based on measuring and analyzing velocities and attenuations of propagated shear waves. In this review, principles and technical developments of shear wave elastography for viscoelasticity characterization from organ to cellular levels are presented, and different imaging modalities used to track shear wave propagation are described. At a macroscopic scale, techniques for inducing shear waves using an external mechanical vibration, an acoustic radiation pressure or a Lorentz force are reviewed along with imaging approaches proposed to track shear wave propagation, namely ultrasound, magnetic resonance, optical, and photoacoustic means. Then, approaches for theoretical modeling and tracking of shear waves are detailed. Following it, some examples of applications to characterize the viscoelasticity of various organs are given. At a microscopic scale, a novel cellular shear wave elastography method using an external vibration and optical microscopy is illustrated. Finally, current limitations and future directions in shear wave elastography are presented.


2009 ◽  
Author(s):  
Richard R. Bouchard ◽  
Patrick D. Wolf ◽  
Stephen J. Hsu ◽  
Douglas M. Dumont ◽  
Gregg E. Trahey

2021 ◽  
Author(s):  
Marjan Razani

In this work, we explored the potential of measuring shear wave propagation using Optical Coherence Elastography (OCE). Shear waves were generated using a 20 MHz piezoelectric transducer transmitting sine-wave bursts of 400 μs, synchronized with the OCT swept source wavelength sweep. The acoustic radiation force was applied to two gelatin phantoms (differing in gelatin concentration by weight, 8% vs 14%, respectively). Differential OCT phase maps, measured with and without the acoustic radiation force, demonstrate microscopic displacement generated by shear wave propagation in these phantoms of different stiffness. The shear wave speeds for the 14% and 8% gelatin-titanium dioxide phantoms were 2.24 0.06 m/s and 1.49 0.05 m/s and also the shear modulus estimated using SW-OCE was 5.3±0.2 kPa and 2.3±0.1 kPa for the 14% and 8% gelatin-titanium dioxide phantoms, respectively. The results demonstrate the feasibility of this technique for measuring the mechanical properties of tissue.


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