Pulse Wave Imaging (PWI) and arterial stiffness measurement of the human carotid artery: An in vivo feasibility study

2011 ◽  
Author(s):  
Ronny X. Li ◽  
Jianwen Luo ◽  
Tipapon Khamdaeng ◽  
Elisa E. Konofagou
Keyword(s):  
Carotid Artery ◽  
Arterial Stiffness ◽  
Feasibility Study ◽  
Pulse Wave ◽  
Stiffness Measurement ◽  
Wave Imaging ◽  
Human Carotid

scholarly journals Arterial stiffness identification of the human carotid artery using the stress–strain relationship in vivo

Ultrasonics ◽  
2012 ◽  
Vol 52 (3) ◽  
pp. 402-411 ◽  
Author(s):  
T. Khamdaeng ◽  
J. Luo ◽  
J. Vappou ◽  
P. Terdtoon ◽  
E.E. Konofagou
Keyword(s):  
Carotid Artery ◽  
Arterial Stiffness ◽  
Stress Strain ◽  
Stiffness Identification ◽  
Strain Relationship ◽  
Human Carotid

scholarly journals Pulse Wave Imaging in Carotid Artery Stenosis Human Patients in Vivo

2019 ◽  
Vol 45 (2) ◽  
pp. 353-366 ◽  
Author(s):  
Ronny X. Li ◽  
Iason Z. Apostolakis ◽  
Paul Kemper ◽  
Matthew D.J. McGarry ◽  
Ada Ip ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Artery Stenosis ◽  
Pulse Wave ◽  
Artery Stenosis ◽  
Wave Imaging

4D Pulse Wave Imaging with sub aperture compounding in the carotid artery in simulations, phantoms and human subjects

2020 ◽  
Author(s):  
Nirvedh H. Meshram ◽  
Julien Grondin ◽  
Grigorios Marios Karageorgos ◽  
Rachel Weber ◽  
Elisa E. Konofagou
Keyword(s):  
Carotid Artery ◽  
Pulse Wave ◽  
Human Subjects ◽  
Wave Imaging

A Novel Noninvasive Technique for Pulse-Wave Imaging and Characterization of Clinically-Significant Vascular Mechanical Properties In Vivo

2007 ◽  
Vol 29 (3) ◽  
pp. 137-154 ◽  
Author(s):  
Kana Fujikura ◽  
Jianwen Luo ◽  
Viktor Gamarnik ◽  
Mathieu Pernot ◽  
Royd Fukumoto ◽  
...  
Keyword(s):  
Aortic Wall ◽  
Pulse Wave ◽  
Distal Region ◽  
Noninvasive Technique ◽  
Abdominal Aortic ◽  
Wave Imaging ◽  
Risk Patients ◽  
Noninvasive Mapping ◽  
Clinically Significant

The pulse-wave velocity (PWV) has been used as an indicator of vascular stiffness, which can be an early predictor of cardiovascular mortality. A noninvasive, easily applicable method for detecting the regional pulse wave (PW) may contribute as a future modality for risk assessment. The purpose of this study was to demonstrate the feasibility and reproducibility of PW imaging (PWI) during propagation along the abdominal aortic wall by acquiring electrocardiography-gated (ECG-gated) radiofrequency (rf) signals noninvasively. An abdominal aortic aneurysm (AAA) was induced using a CaCl2 model in order to investigate the utility of this novel method for detecting disease. The abdominal aortas of twelve normal and five CaCl2, mice were scanned at 30 MHz and electrocardiography (ECG) was acquired simultaneously. The radial wall velocities were mapped with 8000 frames/s. Propagation of the PW was demonstrated in a color-coded ciné-loop format in all cases. In the normal mice, the wave propagated in linear fashion from a proximal to a distal region. However, in CaCl2 mice, multiple waves were initiated from several regions (i.e., most likely initiated from various calcified regions within the aortic wall). The regional PWV in normal aortas was 2.70 ± 0.54 m/s ( r2 = 0.85 ± 0.06, n = 12), which was in agreement with previous reports using conventional techniques. Although there was no statistical difference in the regional PWV between the normal and CaCl2-treated aortas (2.95 ± 0.90 m/s ( r2 = 0.51 ± 0.22, n = 5)), the correlation coefficient was found to be significantly lower in the CaCl2-treated aortas ( p<0.01). This state-of-the-art technique allows noninvasive mapping of vascular disease in vivo. In future clinical applications, it may contribute to the detection of early stages of cardiovascular disease, which may decrease mortality among high-risk patients.

scholarly journals Feasibility and Validation of 4-D Pulse Wave Imaging in Phantoms and In Vivo

2017 ◽  
Vol 64 (9) ◽  
pp. 1305-1317 ◽  
Author(s):  
Iason-Zacharias Apostolakis ◽  
Pierre Nauleau ◽  
Clement Papadacci ◽  
Matthew D. McGarry ◽  
Elisa E. Konofagou
Keyword(s):  
Pulse Wave ◽  
Wave Imaging
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