P4A-5 3D Cardiac Strain Estimation Using Spatio-Temporal Elastic Registration: In Silico Validation

Author(s):  
An Elen ◽  
Dirk Loeckx ◽  
Hon Fai Choi ◽  
Hang Gao ◽  
Piet Claus ◽  
...  
Author(s):  
An Elen ◽  
Dirk Loeckx ◽  
Andras Horvath ◽  
Frederik Maes ◽  
Javier Ganame ◽  
...  

2021 ◽  
Author(s):  
Mallampalli Kapardi ◽  
Madhav Pithapuram ◽  
Raghu Seshadri Iyengar ◽  
Mandayam Rangayyan Yashaswini ◽  
Avinash Kumar Singh ◽  
...  

Virtual patients and physiologies allow experimentation, design, and early-stage clinical trials in-silico. Virtual patient technology for human movement systems that encompasses musculoskeleton and its neural control are few and far in between. In this work, we present one such neuro-musculoskeletal upper limb in-silico model. This upper limb is both modular in architecture and generates movement as an emergent phenomenon out of a multiscale co-simulation of spinal cord neural control and musculoskeletal dynamics. It is developed on the NEUROiD movement simulation platform that enables a co-simulation of popular neural simulator NEURON and the musculoskeletal simulator OpenSim. In this work, we describe the design and development of the upper limb in a modular fashion, while reusing existing models and modules. We further characterize and demonstrate the use of this model in generating a range of commonly observed movements by means of a spatio temporal stimulation pattern delivered to the cervical spinal cord. We believe this work enables a first and small step towards an in-silico paradigms for understanding upper limb movement, disease pathology, medication, and rehabilitation. Index Terms : co-simulation, in-silico, NEUROiD, neuromusculoskeletal, upper limb, Virtual patient.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Jayendra M. Bhalodiya ◽  
Arnab Palit ◽  
Enzo Ferrante ◽  
Manoj K. Tiwari ◽  
Sunil K. Bhudia ◽  
...  

2008 ◽  
Author(s):  
An Elen ◽  
Dirk Loeckx ◽  
Hon Fai Choi ◽  
Hang Gao ◽  
Piet Claus ◽  
...  

PAMM ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ezgi Berberoğlu ◽  
Christian Stoeck ◽  
Philippe Moireau ◽  
Sebastian Kozerke ◽  
Martin Genet

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