5D-2 Application of a Portable RF Impedance Spectrum Analyzer for the Investigation of Lateral Field Excited Acoustic Wave Sensors in a Liquid Environment

Author(s):  
U. Hempel ◽  
T. Schneider ◽  
S. Doerner ◽  
R. Lucklum ◽  
P. R. Hauptmann ◽  
...  
Author(s):  
D.F. McCann ◽  
J.M. Parks ◽  
J.M. McGann ◽  
M.P. da Cunha ◽  
J.F. Vetelino

Author(s):  
Fang Li ◽  
Lifeng Qin ◽  
Qing-Ming Wang

Cell-based biosensors have the capacity to respond to a wide range of analytes in a physiologically relevant manner. By employing living cells as sensors, bioanalytes can be screened without requiring apriori knowledge of the analyte’s chemistry. The ability to operate and screen for unknown analytes provides benefits in numerous applications, including pharmacology, cell biology, toxicology, and environmental monitoring. Recent studies have demonstrated that acoustic wave devices are capable of quantitatively probing the behaviors of cells attaching to sensor surface. Among various types of acoustic devices, Love mode sensor has many advantages in liquid environment. However, up to now, the use of Love mode devices as cell-based sensors is limited, including theoretical and experimental studies. In this study, we developed a theoretical model for cell-based Love mode sensors. The devices were designed, fabricated and utilized for cell adhesion monitoring.


2013 ◽  
Vol 791-793 ◽  
pp. 545-549
Author(s):  
Jia Lin Jiang ◽  
Ting Feng Ma

Lateral field excitation (LFE) acoustic wave devices, which employ two electrodes on the same surface of a piezoelectric substrate, have been found attractive in sensing applications. However, up to now, the sensitivities of pure-LFE devices based on LiNbO3 single crystal is unknown. In this work, the effective LFE exciting electric field direction of (yxl)89° LiNbO3 is determined. The calculated results showed that when the driving electric field direction is perpendicular to the crystallographic X-axis of the piezoelectric substrate, (yxl)89° LiNbO3 LFE device works on pure-LFE mode. Based on this, several LiNbO3 pure-LFE bulk acoustic wave sensors with three different electrodes are designed and fabricated. The results show that the (yxl)89° LiNbO3 LFE sensor with interdigital electrodes is 11.1 times and 2.2 times more sensitive to changes in liquid conductivity compared to traditional LFE devices with single gap circular electrodes and Archimedes spiral electrodes, respectively. The results are important for investigating high-sensitivity LFE bulk acoustic wave sensors by using LiNbO3 single crystal.


2011 ◽  
Vol 156 (2) ◽  
pp. 969-975 ◽  
Author(s):  
Wenyan Wang ◽  
Chao Zhang ◽  
Yan Liu ◽  
Tianhuai Ding

2008 ◽  
Author(s):  
A. Kabulski ◽  
V. R. Pagán ◽  
D. Cortes ◽  
R. Burda ◽  
O. M. Mukdadi ◽  
...  

Chemosensors ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 173
Author(s):  
Dana Miu ◽  
Izabela Constantinoiu ◽  
Valentina Dinca ◽  
Cristian Viespe

Laser-deposited gold immobilization layers having different porosities were incorporated into love wave surface acoustic wave sensors (LW-SAWs). Variation of pulsed laser deposition parameters allows good control of the gold film morphology. Biosensors with various gold film porosities were tested using the biotin–avidin reaction. Control of the Au layer morphology is important since the biotin and avidin layer morphologies closely follow that of the gold. The response of the sensors to biotin/avidin, which is a good indicator of biosensor performance, is improved when the gold layer has increased porosity. Given the sizes of the proteins, the laser-deposited porous gold interfaces have optimal pore dimensions to ensure protein stability.


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