Mechanical Properties of Single Cells by High-Frequency Time-Resolved Acoustic Microscopy

2007 ◽  
Vol 54 (11) ◽  
pp. 2257-2271 ◽  
Author(s):  
Eike C. Weiss ◽  
Pavlos Anastasiadis ◽  
Gotz Pilarczyk ◽  
Robert M. Lemor ◽  
Pavel V. Zinin
2018 ◽  
Vol 12 (1) ◽  
pp. 69-85 ◽  
Author(s):  
Pavlos Anastasiadis ◽  
Pavel V. Zinin

High-frequency focused ultrasound has emerged as a powerful modality for both biomedical imaging and elastography. It is gaining more attention due to its capability to outperform many other imaging modalities at a submicron resolution. Besides imaging, high-frequency ultrasound or acoustic biomicroscopy has been used in a wide range of applications to assess the elastic and mechanical properties at the tissue and single cell level. The interest in acoustic microscopy stems from the awareness of the relationship between biomechanical and the underlying biochemical processes in cells and the vast impact these interactions have on the onset and progression of disease. Furthermore, ultrasound biomicroscopy is characterized by its non-invasive and non-destructive approach. This, in turn, allows for spatiotemporal studies of dynamic processes without the employment of histochemistry that can compromise the integrity of the samples. Numerous techniques have been developed in the field of acoustic microscopy. This review paper discusses high-frequency ultrasound theory and applications for both imaging and elastography.


2021 ◽  
Vol 129 (21) ◽  
pp. 215305
Author(s):  
Wei Zhao ◽  
Baptiste Bérenguier ◽  
Cendra Rakotoarimanana ◽  
Anne-Marie Gonçalves ◽  
Arnaud Etcheberry ◽  
...  

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