Performance evaluation of A-SPECT: a high resolution desktop pinhole SPECT system for imaging small animals

2002 ◽  
Vol 49 (5) ◽  
pp. 2139-2147 ◽  
Author(s):  
D.P. McElroy ◽  
L.R. MacDonald ◽  
F.J. Beekman ◽  
Yuchuan Wang ◽  
B.E. Patt ◽  
...  
Keyword(s):  
Performance Evaluation ◽  
High Resolution ◽  
Small Animals ◽  
Pinhole Spect ◽  
Spect System

Performance Evaluation of Stationary and Semi-Stationary Acquisition with a Non-Stationary Small Animal Multi-Pinhole SPECT System

2013 ◽  
Vol 16 (3) ◽  
pp. 311-316 ◽  
Author(s):  
Catharina Lange ◽  
Ivayla Apostolova ◽  
Mathias Lukas ◽  
Kai P. Huang ◽  
Frank Hofheinz ◽  
...  
Keyword(s):  
Performance Evaluation ◽  
Small Animal ◽  
Pinhole Spect ◽  
Spect System

scholarly journals Performance evaluation of a newly developed high-resolution, dual-head animal SPECT system based on the NEMA NU1-2007 standard

2014 ◽  
Vol 15 (6) ◽  
pp. 267-278 ◽  
Author(s):  
Vahideh Moji ◽  
Navid Zeraatkar ◽  
Mohammad Hossein Farahani ◽  
Mahmood Reza Aghamiri ◽  
Salar Sajedi ◽  
...  
Keyword(s):  
Performance Evaluation ◽  
High Resolution ◽  
Spect System

System design and development of a pinhole SPECT system for quantitative functional imaging of small animals

2006 ◽  
Vol 20 (3) ◽  
pp. 245-251 ◽  
Author(s):  
Toshiyuki Aoi ◽  
Tsutomu Zeniya ◽  
Hiroshi Watabe ◽  
Hossain M. Deloar ◽  
Tetsuya Matsuda ◽  
...  
Keyword(s):  
System Design ◽  
Functional Imaging ◽  
Small Animals ◽  
Design And Development ◽  
Pinhole Spect ◽  
Spect System

PERFORMANCE EVALUATION OF THE HIGH RESOLUTION SMALL ANIMAL PET SCANNER

2003 ◽  
Vol 15 (04) ◽  
pp. 143-149 ◽  
Author(s):  
SENG-PENG MOK ◽  
CHAO-HSING WANG ◽  
JYH-CHENG CHEN ◽  
REN-SHYAN LIU
Keyword(s):  
Performance Evaluation ◽  
Molecular Imaging ◽  
High Resolution ◽  
Spatial Resolution ◽  
Energy Resolution ◽  
Small Animal ◽  
Tangential Direction ◽  
Small Animal Pet ◽  
Small Animals

Molecular imaging is an important technology to clarify biological and medical uncertainties in the 21th century. This is best realized via in vivo imaging of biological processes in small animals. Thus, a special high resolution imager dedicated for small animals is required. We recently installed a high resolution animal positron emission tomography (PET) scanner (microPET R4) for doing in vivo molecular imaging of gene expression. This paper describes the performance evaluation of our microPET R4 scanner. The microPET R4 scanner is a dedicated PET for studies of rodents. The system is composed of 96 detector modules, each with an 8 × 8 array of 2.1 × 2.1 × 10 mm3 lutetium oxyorthosilicate (LSO) crystals, arranged as 32 crystal rings and 14.8 cm in diameter. The detector crystals are coupled to a Hamamatsu R5900-C8 position sensitive photomultiplier tube (PS-PMT) via a 10 cm long optical fiber bundle. The system operates in 3D mode without inter-plane septa, acquiring data in list mode. A number of scanner parameters such as sensitivity, spatial resolution and energy resolution were determined in this work. In the center of field of view (FOV) a maximal sensitivity of 21.04 cps/kBq was calculated from a measurement with a germanium-68 point source with an energy window of 250-750 keV. Spatial resolution of 2.03 mm (FORB+2D-FBPJ/1.61 mm (FORB + 2D-OSEM) full width at half maximum (FWHM) in the tangential direction and 2.07 mm (2D-FBP)/1.65 mm (2D-OSEM) FWHM in the radial direction were measured in the center with a 0.28 mm diameter 18F-FDG line source. The energy resolution of the scanner was measured across all crystals ranging from 13.9% to around 34.6% with a mean of 18.45%. The results show that the microPET R4 is a suitable PET scanner for imaging small animals like mice and rats.

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