Functional Imaging of Spinal Cord Electrical Activity From Its Evoked Magnetic Field

2009 ◽  
Vol 56 (10) ◽  
pp. 2452-2460 ◽  
Author(s):  
Tomoya Sato ◽  
Yoshiaki Adachi ◽  
Masaki Tomori ◽  
Senichi Ishii ◽  
Shigenori Kawabata ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Spinal Cord ◽  
Electrical Activity ◽  
Functional Imaging

scholarly journals DEVELOPING NEW METHODS OF SPINAL CORD INJURY TREATMENT USING MAGNETIC NANOPARTICLES IN COMBINATION WITH ELECTROMAGNETIC FIELD

2017 ◽  
Vol 16 (2) ◽  
pp. 145-148
Author(s):  
Sergey Kolesov ◽  
Andrey Panteleyev ◽  
Maxim Sazhnev ◽  
Arkadiy Kazmin
Keyword(s):  
Magnetic Field ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Iron Oxide ◽  
Evoked Potential ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide ◽  
Potential Amplitude ◽  
Cord Injury

ABSTRACT Objective: To determine the amount of loss of function after spinal cord transection of varying extents, and whether magnetic iron oxide nanoparticles, in combination with an external magnetic field, improve the rate of subsequent functional recovery in rats. Methods: The animals were divided into groups with 50%, 80% and complete spinal cord transection. The animals of all three study groups were administered magnetic iron oxide nanoparticle suspension to the area of injury. The three control groups were not administered magnetic nanoparticles, but had corresponding transection levels. All animals were exposed to a magnetic field for 4 weeks. Loss of postoperative function and subsequent recovery were assessed using the BBB motor function scale and somatosensory evoked potential monitoring on the first day after surgery, and then weekly. Terminal histological analysis was also conducted in all the groups. Results: The animals in the control or complete transection groups did not demonstrate statistically significant improvement in either the BBB scores or evoked potential amplitude over the four-week period. In the group with 50% transection, however, a statistically significant increase in evoked potential amplitude and BBB scores was observed four weeks after surgery, with the highest increase during the second week of the study. In the group with 80% transection, only improvement in evoked potential amplitude was statistically significant, although less pronounced than in the 50% transection group. Conclusion: The use of magnetic iron oxide nanoparticles in combination with a magnetic field leads to higher rates of functional recovery after spinal cord injury in laboratory animals. The mechanism of this functional improvement needs further investigation.

Single Potential Analysis of Cavernous Electrical Activity in Spinal Cord Injury patients

1994 ◽  
Vol 151 (2) ◽  
pp. 367-372 ◽  
Author(s):  
C.G. Stief ◽  
HöppnerC. Höppner ◽  
D. Sauerwein ◽  
U. Jonas
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Electrical Activity ◽  
Potential Analysis ◽  
Cord Injury ◽  
Single Potential

Interaction between trophic action and electrical activity in spinal cord cultures

1984 ◽  
Vol 15 (2) ◽  
pp. 211-217 ◽  
Author(s):  
Douglas E. Brenneman ◽  
Sandra Fitzgerald ◽  
Phillip G. Nelson
Keyword(s):  
Spinal Cord ◽  
Electrical Activity ◽  
Trophic Action

scholarly journals Noninvasive muscle activity imaging using magnetography

2020 ◽  
Vol 117 (9) ◽  
pp. 4942-4947 ◽  
Author(s):  
Rodolfo R. Llinás ◽  
Mikhail Ustinin ◽  
Stanislav Rykunov ◽  
Kerry D. Walton ◽  
Guilherme M. Rabello ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Contrast Media ◽  
Electrical Activity ◽  
Real Time ◽  
Human Body ◽  
Muscle Activity ◽  
Muscular Activity ◽  
Exponential Increase ◽  
Somatic Musculature ◽  
The Magnetic Field

A spectroscopic paradigm has been developed that allows the magnetic field emissions generated by the electrical activity in the human body to be imaged in real time. The growing significance of imaging modalities in biology is evident by the almost exponential increase of their use in research, from the molecular to the ecological level. The method of analysis described here allows totally noninvasive imaging of muscular activity (heart, somatic musculature). Such imaging can be obtained without additional methodological steps such as the use of contrast media.

The effect of FMRF-amide-like peptides on electrical activity in isolated mammalian spinal cord

1998 ◽  
Vol 30 (4) ◽  
pp. 295-301 ◽  
Author(s):  
Eagle Yi-Kung Huang ◽  
Jeff Bagust ◽  
Ram P. Sharma ◽  
Robert J. Walker
Keyword(s):  
Spinal Cord ◽  
Electrical Activity ◽  
Fmrf Amide
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