Imaging the Cerebral Blood Flow With Enhanced Laser Speckle Contrast Analysis (eLASCA) by Monotonic Point Transformation

2009 ◽  
Vol 56 (4) ◽  
pp. 1127-1133 ◽  
Author(s):  
Peng Miao ◽  
Minheng Li ◽  
Hugues Fontenelle ◽  
Anastasios Bezerianos ◽  
Yihong Qiu ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Point Transformation ◽  
Laser Speckle ◽  
Speckle Contrast ◽  
Contrast Analysis ◽  
Laser Speckle Contrast Analysis

scholarly journals Intraoperative monitoring of cerebral blood flow by laser speckle contrast analysis

2009 ◽  
Vol 27 (4) ◽  
pp. E11 ◽  
Author(s):  
Nils Hecht ◽  
Johannes Woitzik ◽  
Jens P. Dreier ◽  
Peter Vajkoczy
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Radial Artery ◽  
Laser Speckle ◽  
Radial Artery Graft ◽  
Speckle Contrast ◽  
Hemodynamic Compromise ◽  
Artery Graft ◽  
Contrast Analysis ◽  
Laser Speckle Contrast Analysis

Object Currently, reliable low-cost and noninvasive techniques to assess cerebral perfusion in the operating room are not available. The authors report on their first clinical experience with laser speckle contrast analysis (LASCA) as a complementary imaging tool for the noninvasive and dynamic assessment of cerebral blood flow (CBF) during neurovascular surgery. The purpose of this preliminary study was to address the general feasibility of LASCA in terms of handling and image quality and to provide an example of its clinical implications. Methods Laser speckle contrast analysis was performed in patients undergoing cerebral revascularization procedures for the treatment of hemodynamic compromise and complex aneurysms. The portable LASCA device was centered over the surgical field, and continuous 5-minute recordings of relative CBF were obtained. In the case of flow augmentation for hemodynamic compromise, CBF monitoring was performed before and after completion of the anastomosis. In the case of flow replacement for parent artery sacrifice, CBF monitoring was performed during consecutive 30-second test occlusions of the radial artery graft after proximal internal carotid artery sacrifice and the subsequent initiation of blood flow through the bypass. Results In all cases, the authors achieved good visualization of relative CBF in addition to flow imaging in both the bypass graft and the cortical vasculature. During a sudden CBF decrease after test occlusion of the radial artery graft and subsequent flow initiation through the bypass, LASCA allowed immediate visualization and measurement of relative CBF in excellent spatiotemporal resolution. Conclusions In this study LASCA offered noninvasive and rapid intraoperative assessment of relative CBF, which can be used for optimizing neurovascular procedures.

Laser Speckle Contrast Analysis (LASCA) for Measuring Blood Flow

2012 ◽  
pp. 147-163 ◽  
Author(s):  
J. David Briers ◽  
Paul M. McNamara ◽  
Marie Louise O'Connell ◽  
Martin J. Leahy
Keyword(s):  
Blood Flow ◽  
Laser Speckle ◽  
Speckle Contrast ◽  
Contrast Analysis ◽  
Laser Speckle Contrast Analysis
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