scholarly journals Minimum-Time Thermal Dose Control of Thermal Therapies

2005 ◽  
Vol 52 (2) ◽  
pp. 191-200 ◽  
Author(s):  
D. Arora ◽  
M. Skliar ◽  
R.B. Roemer
Keyword(s):  
Minimum Time ◽  
Thermal Dose ◽  
Thermal Therapies ◽  
Dose Control

Constrained Predictive Control of Thermal Therapies for Minimum-Time Delivery of Thermal Dose

2007 ◽  
Vol 15 (6) ◽  
pp. 1030-1037 ◽  
Author(s):  
Dhiraj Arora ◽  
Mikhail Skliar ◽  
Daniel Cooley ◽  
Robert B. Roemer
Keyword(s):  
Predictive Control ◽  
Minimum Time ◽  
Thermal Dose ◽  
Thermal Therapies

MR thermometry-based feedback control of efficacy and safety in minimum-time thermal therapies: Phantom andin-vivoevaluations

2006 ◽  
Vol 22 (1) ◽  
pp. 29-42 ◽  
Author(s):  
Dhiraj Arora ◽  
Daniel Cooley ◽  
Trent Perry ◽  
Junyu Guo ◽  
Andrew Richardson ◽  
...  
Keyword(s):  
Feedback Control ◽  
Minimum Time ◽  
Efficacy And Safety ◽  
Mr Thermometry ◽  
Thermal Therapies

An Analytical Evaluation of the Optimal Thermal Dose Delivery Parameters for Thermal Therapies

2003 ◽  
Author(s):  
Kung-Shan Cheng ◽  
Robert B. Roemer
Keyword(s):  
Blood Flow ◽  
Treatment Time ◽  
Heating Time ◽  
Treatment Temperature ◽  
Thermal Dose ◽  
Dose Delivery ◽  
Thermal Therapies ◽  
Initial Power ◽  
High Treatment ◽  
Optimal Heating

This study derives the first analytic solution for evaluating the optimal treatment parameters needed for delivering a desired thermal dose during thermal therapies consisting of a single heating pulse. Each treatment is divided into four time periods (two power-on and two power-off), and the thermal dose delivered during each of those periods is evaluated using the non-linear Sapareto and Dewey equation relating thermal dose to temperature and time. The results reveal that the thermal dose delivered during the second power-on period when T>43C (TD2) and the initial power-off period when T>43C (TD3) contribute the major portions of the total thermal dose needed for a successful treatment (taken as 240 CEM43°C), and that TD3 dominates for treatments with higher peak temperatures. For a fixed perfusion value, the analytical results show that once the maximum treatment temperature and the total thermal dose (e.g., 240 CEM43°C) are specified, then the required heating time and the applied power magnitude are uniquely determined. These are the optimal heating parameters since lower/higher values result in under-dosing/over-dosing of the treated region. It is also shown that higher maximum treatment temperatures result in shorter treatment times, and for each patient blood flow there is a maximum allowable temperature that can be used to reach the desired thermal dose. In addition, since TD2 and TD3 contribute most of the total thermal dose, and they are both significantly affected by the blood flow present for high treatment temperatures, these results show that perfusion effects must be considered when attempting to optimize high temperature thermal therapy treatments (no excess thermal dose delivered, minimum power applied and shortest treatment time attained).

scholarly journals Direct thermal dose control of constrained focused ultrasound treatments: phantom andin vivoevaluation

2005 ◽  
Vol 50 (8) ◽  
pp. 1919-1935 ◽  
Author(s):  
Dhiraj Arora ◽  
Daniel Cooley ◽  
Trent Perry ◽  
Mikhail Skliar ◽  
Robert B Roemer
Keyword(s):  
Focused Ultrasound ◽  
Thermal Dose ◽  
Dose Control

Constrained model-predictive thermal dose control for MRI-guided ultrasound thermal treatments (Invited Paper)

2005 ◽  
Author(s):  
Dhiraj Arora ◽  
Trent Perry ◽  
Daniel Cooley ◽  
Junyu Guo ◽  
Rock Hadley ◽  
...  
Keyword(s):  
Thermal Treatments ◽  
Thermal Dose ◽  
Dose Control ◽  
Mri Guided ◽  
Constrained Model
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