Classifier Result Aggregation for Automatically Grading Histopathological Images

Author(s):  
Catalin Stoean ◽  
Daniel Lichtblau
Author(s):  
Inzamam Mashood Nasir ◽  
Muhammad Rashid ◽  
Jamal Hussain Shah ◽  
Muhammad Sharif ◽  
Muhammad Yahiya Haider Awan ◽  
...  

Background: Breast cancer is considered as the most perilous sickness among females worldwide and the ratio of new cases is expanding yearly. Many researchers have proposed efficient algorithms to diagnose breast cancer at early stages, which have increased the efficiency and performance by utilizing the learned features of gold standard histopathological images. Objective: Most of these systems have either used traditional handcrafted features or deep features which had a lot of noise and redundancy, which ultimately decrease the performance of the system. Methods: A hybrid approach is proposed by fusing and optimizing the properties of handcrafted and deep features to classify the breast cancer images. HOG and LBP features are serially fused with pretrained models VGG19 and InceptionV3. PCR and ICR are used to evaluate the classification performance of proposed method. Results: The method concentrates on histopathological images to classify the breast cancer. The performance is compared with state-of-the-art techniques, where an overall patient-level accuracy of 97.2% and image-level accuracy of 96.7% is recorded. Conclusion: The proposed hybrid method achieves the best performance as compared to previous methods and it can be used for the intelligent healthcare systems and early breast cancer detection.


2020 ◽  
Vol 14 ◽  
Author(s):  
Lahari Tipirneni ◽  
Rizwan Patan

Abstract:: Millions of deaths all over the world are caused by breast cancer every year. It has become the most common type of cancer in women. Early detection will help in better prognosis and increases the chance of survival. Automating the classification using Computer-Aided Diagnosis (CAD) systems can make the diagnosis less prone to errors. Multi class classification and Binary classification of breast cancer is a challenging problem. Convolutional neural network architectures extract specific feature descriptors from images, which cannot represent different types of breast cancer. This leads to false positives in classification, which is undesirable in disease diagnosis. The current paper presents an ensemble Convolutional neural network for multi class classification and Binary classification of breast cancer. The feature descriptors from each network are combined to produce the final classification. In this paper, histopathological images are taken from publicly available BreakHis dataset and classified between 8 classes. The proposed ensemble model can perform better when compared to the methods proposed in the literature. The results showed that the proposed model could be a viable approach for breast cancer classification.


2021 ◽  
Author(s):  
Zhuangzhuang Wang ◽  
Mengning Yang ◽  
Yangfan Lyu ◽  
Kairun Chen ◽  
Qicheng Tang

Author(s):  
Xiansong Huang ◽  
Hongliang He ◽  
Pengxu Wei ◽  
Chi Zhang ◽  
Juncen Zhang ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tuan D. Pham

AbstractImage analysis in histopathology provides insights into the microscopic examination of tissue for disease diagnosis, prognosis, and biomarker discovery. Particularly for cancer research, precise classification of histopathological images is the ultimate objective of the image analysis. Here, the time-frequency time-space long short-term memory network (TF-TS LSTM) developed for classification of time series is applied for classifying histopathological images. The deep learning is empowered by the use of sequential time-frequency and time-space features extracted from the images. Furthermore, unlike conventional classification practice, a strategy for class modeling is designed to leverage the learning power of the TF-TS LSTM. Tests on several datasets of histopathological images of haematoxylin-and-eosin and immunohistochemistry stains demonstrate the strong capability of the artificial intelligence (AI)-based approach for producing very accurate classification results. The proposed approach has the potential to be an AI tool for robust classification of histopathological images.


Cancers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 2419
Author(s):  
Georg Steinbuss ◽  
Mark Kriegsmann ◽  
Christiane Zgorzelski ◽  
Alexander Brobeil ◽  
Benjamin Goeppert ◽  
...  

The diagnosis and the subtyping of non-Hodgkin lymphoma (NHL) are challenging and require expert knowledge, great experience, thorough morphological analysis, and often additional expensive immunohistological and molecular methods. As these requirements are not always available, supplemental methods supporting morphological-based decision making and potentially entity subtyping are required. Deep learning methods have been shown to classify histopathological images with high accuracy, but data on NHL subtyping are limited. After annotation of histopathological whole-slide images and image patch extraction, we trained and optimized an EfficientNet convolutional neuronal network algorithm on 84,139 image patches from 629 patients and evaluated its potential to classify tumor-free reference lymph nodes, nodal small lymphocytic lymphoma/chronic lymphocytic leukemia, and nodal diffuse large B-cell lymphoma. The optimized algorithm achieved an accuracy of 95.56% on an independent test set including 16,960 image patches from 125 patients after the application of quality controls. Automatic classification of NHL is possible with high accuracy using deep learning on histopathological images and routine diagnostic applications should be pursued.


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