Investigating Landscape Topology for Subpopulation Differentiation in Genetic Chromodynamics

2008 ◽  
Author(s):  
Ruxandra Stoean ◽  
Catalin Stoean ◽  
D. Dumitrescu
Keyword(s):  
Subpopulation Differentiation

SUBPOPULATION DIFFERENTIATION ASSOCIATED WITH NONRIBOSOMAL PEPTIDE SYNTHETASE GENE CLUSTER DYNAMICS IN THE CYANOBACTERIUM PLANKTOTHRIX SPP.1

2010 ◽  
Vol 46 (4) ◽  
pp. 645-652 ◽  
Author(s):  
Trine B. Rounge ◽  
Thomas Rohrlack ◽  
Beatriz Decenciere ◽  
Bente Edvardsen ◽  
Tom Kristensen ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Nonribosomal Peptide Synthetase ◽  
Nonribosomal Peptide ◽  
Peptide Synthetase ◽  
Subpopulation Differentiation

scholarly journals Restricted gene flow and subpopulation differentiation in Silene dioica

Heredity ◽  
1998 ◽  
Vol 80 (6) ◽  
pp. 715-723 ◽  
Author(s):  
Barbara E Giles ◽  
Elisabeth Lundqvist ◽  
Jérôme Goudet
Keyword(s):  
Gene Flow ◽  
Restricted Gene Flow ◽  
Silene Dioica ◽  
Subpopulation Differentiation

scholarly journals Differential breeding practices drive subpopulation differentiation and contribute to the loss of genetic diversity within dog breed lineages

2020 ◽  
Author(s):  
Sara Lampi ◽  
Jonas Donner ◽  
Heidi Anderson ◽  
Jaakko L. O. Pohjoismäki
Keyword(s):  
Genetic Diversity ◽  
Gene Flow ◽  
Genetic Differentiation ◽  
Snp Array ◽  
Population Fragmentation ◽  
Genome Wide ◽  
A Genome ◽  
Key Drivers ◽  
Loss Of Genetic Diversity ◽  
Subpopulation Differentiation

Abstract Background Discrete breed ideals are not restricted to delimiting dog breeds from another, but also are key drivers of subpopulation differentiation. As genetic differentiation due to population fragmentation results in increased rates of inbreeding and loss of genetic diversity, detecting and alleviating the reasons of population fragmentation can provide effective tools for the maintenance of healthy dog breeds. Results Using a genome wide SNP array, we detected genetic differentiation to subpopulations in six breeds, Belgian Shepherd, English Greyhound, Finnish Lapphund, Italian Greyhound, Labrador Retriever and Shetland Sheepdog, either due to geographical isolation or as a result of differential breeding strategies. The subpopulation differentiation was strongest in show dog lineages. Conclusions Besides geographical differentiation caused by founder effect and lack of gene flow, selection on champion looks or restricted pedigrees is a strong driver of population fragmentation. Artificial barriers for gene flow between the different subpopulations should be recognized and abolished for the maintenance of genetic diversity within a breed.

scholarly journals Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages

2020 ◽  
Author(s):  
Sara Lampi ◽  
Jonas Donner ◽  
Heidi Anderson ◽  
Jaakko L. O. Pohjoismäki
Keyword(s):  
Genetic Diversity ◽  
Gene Flow ◽  
Genetic Differentiation ◽  
Association Studies ◽  
Genome Wide Association Studies ◽  
Population Fragmentation ◽  
Genome Wide ◽  
A Genome ◽  
Loss Of Genetic Diversity ◽  
Subpopulation Differentiation

Abstract Background: Discrete breed ideals are not restricted to delimiting dog breeds from another, but also are key drivers of subpopulation differentiation. As genetic differentiation due to population fragmentation results in increased rates of inbreeding and loss of genetic diversity, detecting and alleviating the reasons of population fragmentation can provide effective tools for the maintenance of healthy dog breeds. Results: Using a genome wide SNP array, we detected genetic differentiation to subpopulations in six breeds, Belgian Shepherd, English Greyhound, Finnish Lapphund, Italian Greyhound, Labrador Retriever and Shetland Sheepdog, either due to geographical isolation or as a result of differential breeding strategies. The subpopulation differentiation was strongest in show dog lineages.Conclusions: Besides geographical differentiation caused by founder effect and lack of gene flow, selection on champion looks or restricted pedigrees is a strong driver of population fragmentation. Artificial barriers for gene flow between the different subpopulations should be recognized, their necessity evaluated critically and perhaps abolished in order to maintain genetic diversity within a breed. Subpopulation differentiation might also result in false positive signals in genome-wide association studies of different traits.Lay summary: Purebred dogs are, by definition, reproductively isolated from other breeds. However, similar isolation can also occur within a breed due to conflicting breeder ideals and geographic distances between the dog populations. We show here that both of these examples can contribute to breed division, with subsequent loss of genetic variation in the resulting breed lineages. Breeders should avoid creating unnecessary boundaries between breed lineages and facilitate the exchange of dogs between countries.

Sign in / Sign up

Export Citation Format

Share Document