Applying Large-Scale Multi-unit Combinatorial Auctions with Reserve-Price Biddings for Resource Allocations -- A Preliminary Analysis

Author(s):  
Naoki Fukuta
2020 ◽  
Author(s):  
Miguel Araujo-Voces ◽  
Victor Quesada

Abstract Background Through its ability to open pores in cell membranes, perforin-1 plays a key role in the immune system. Consistent with this role, the gene encoding perforin shows hallmarks of complex evolutionary events, including amplification and pseudogenization, in multiple species. A large proportion of these events occurred in phyla for which scarce genomic data were available. However, recent large-scale genomics projects have added a wealth of information on those phyla. Using this input, we annotated perforin-1 homologs in more than eighty species including mammals, reptiles, birds, amphibians and fishes. Results We have annotated more than 400 perforin genes in all groups studied. Most mammalian species only have one perforin locus, which may contain a related pseudogene. However, we found four independent small expansions in unrelated members of this class. We could reconstruct the full-length coding sequences of only a few avian perforin genes, although we found incomplete and truncated forms of these gene in other birds. In the rest of reptilia, perforin-like genes can be found in at least three different loci containing up to twelve copies. Notably, mammals, non-avian reptiles, amphibians, and possibly teleosts share at least one perforin-1 locus as assessed by flanking genes. Finally, fish genomes contain multiple perforin loci with varying copy numbers and diverse exon/intron patterns. We have also found evidence for shorter genes with high similarity to the C2 domain of perforin in several teleosts. A preliminary analysis suggests that these genes arose at least twice during evolution from perforin-1 homologs. Conclusions The assisted annotation of new genomic assemblies shows complex patterns of birth-and-death events in the evolution of perforin. These events include duplication/pseudogenization in mammals, multiple amplifications and losses in reptiles and fishes and at least one case of partial duplication with a novel start codon in fishes.


2012 ◽  
Vol 472-475 ◽  
pp. 2385-2388
Author(s):  
Qian Shi ◽  
Rui Huang

Large-scale public building (LSPB) is different from general industrial and civil construction, so that some special management methods are attained to handling the complex design environment based on sustainable development theory. Including organization model, design checklist and some interface design management principles are raised in this analysis.


2019 ◽  
Vol 9 (3) ◽  
pp. 395 ◽  
Author(s):  
Sung-Min Kim ◽  
Myeongchan Oh ◽  
Hyeong-Dong Park

Photovoltaic (PV) energy is one of the most promising renewable energies in the world due to its ubiquity and sustainability. However, installation of solar panels on the ground can cause some problems, especially in countries where there is not enough space for installation. As an alternative, floating PV, with advantages in terms of efficiency and environment, has attracted attention, particularly with regard to installing large-scale floating PV for dam lakes and reservoirs in Korea. In this study, the potentiality of floating PV is evaluated, and the power production is estimated for 3401 reservoirs. To select a suitable reservoir for floating PV installation, we constructed and analyzed the water depth database using OpenAPI. We also used the typical meteorological year (TMY) data and topographical information to predict the irradiance distribution. As a result, the annual power production by all possible reservoirs was estimated to be 2932 GWh, and the annual GHG reduction amount was approximately 1,294,450 tons. In particular, Jeollanam-do has many reservoirs and was evaluated as suitable for floating PV installation because of its high solar irradiance. The results can be used to estimate priorities and potentiality as a preliminary analysis for floating PV installation.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Miguel Araujo-Voces ◽  
Víctor Quesada

Abstract Background Through its ability to open pores in cell membranes, perforin-1 plays a key role in the immune system. Consistent with this role, the gene encoding perforin shows hallmarks of complex evolutionary events, including amplification and pseudogenization, in multiple species. A large proportion of these events occurred in phyla for which scarce genomic data were available. However, recent large-scale genomics projects have added a wealth of information on those phyla. Using this input, we annotated perforin-1 homologs in more than eighty species including mammals, reptiles, birds, amphibians and fishes. Results We have annotated more than 400 perforin genes in all groups studied. Most mammalian species only have one perforin locus, which may contain a related pseudogene. However, we found four independent small expansions in unrelated members of this class. We could reconstruct the full-length coding sequences of only a few avian perforin genes, although we found incomplete and truncated forms of these gene in other birds. In the rest of reptilia, perforin-like genes can be found in at least three different loci containing up to twelve copies. Notably, mammals, non-avian reptiles, amphibians, and possibly teleosts share at least one perforin-1 locus as assessed by flanking genes. Finally, fish genomes contain multiple perforin loci with varying copy numbers and diverse exon/intron patterns. We have also found evidence for shorter genes with high similarity to the C2 domain of perforin in several teleosts. A preliminary analysis suggests that these genes arose at least twice during evolution from perforin-1 homologs. Conclusions The assisted annotation of new genomic assemblies shows complex patterns of birth-and-death events in the evolution of perforin. These events include duplication/pseudogenization in mammals, multiple amplifications and losses in reptiles and fishes and at least one case of partial duplication with a novel start codon in fishes.


2014 ◽  
Vol 60 (5) ◽  
pp. 1180-1201 ◽  
Author(s):  
Sang Won Kim ◽  
Marcelo Olivares ◽  
Gabriel Y. Weintraub

2016 ◽  
Vol 826 ◽  
pp. 71-74
Author(s):  
Zhi Ying Gao ◽  
Chao Yang ◽  
Rui Tian ◽  
Wei Dong Ji ◽  
Ya Qing Gong ◽  
...  

This paper analyzes the bus operation condition under the cold and high altitude city such as Hohhot in Inner Mongolia. According to the exist problems for 5 kinds of move buses, 4 different brands hybrid buses and a conventional bus, the reliability of the whole bus was analyzed. It wants to find the various factors impact on the bus reliability under different conditions. Thus, the properties of the hybrid bus can be improved, the fundamental data and experience for the large-scale production has been accumulated.


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