scholarly journals DASH: A New Language for Declarative Behavioural Requirements with Control State Hierarchy

2017 ◽  
Author(s):  
Jose Serna ◽  
Nancy A. Day ◽  
Sabria Farheen
Keyword(s):  
Control State

Cognitive control of convergent and divergent thinking: A control-state approach to human creativity

2013 ◽  
Author(s):  
Bernhard Hommel ◽  
Soghra Akbari Chermahini ◽  
Wery P. M. van den Wildenberg ◽  
Lorenza S. Colzato
Keyword(s):  
Cognitive Control ◽  
Divergent Thinking ◽  
Human Creativity ◽  
Control State

scholarly journals Effects of Diabetes Mellitus Induced by Alloxan on the Pharmacokinetics of Metformin in Rats: Restoration of Pharmacokinetic Parameters to the Control State by Insulin Treatment

2008 ◽  
Vol 11 (1) ◽  
pp. 88 ◽  
Author(s):  
Myung G. Lee ◽  
Young H Choi ◽  
Inchul Lee
Keyword(s):  
Diabetes Mellitus ◽  
Oral Administration ◽  
Protein Expression ◽  
Intravenous Administration ◽  
Insulin Treatment ◽  
Pharmacokinetic Parameters ◽  
Mrna Levels ◽  
Altered Pharmacokinetic ◽  
Intravenous And Oral Administration ◽  
Control State

To test the effect of insulin treatment on the pharmacokinetics of metformin in rats with diabetes mellitus induced by alloxan (DMIA rats). The following results were reported from other studies. Metformin was metabolized via hepatic CYP2C11, 2D1, and 3A1/2 in rats. In DMIA rats, the protein expression and mRNA levels of hepatic CYP2C11 and 3A1/2 decreased and increased, respectively. In rat model of diabetes mellitus induced by streptozotocin, the protein expression of hepatic CYP2D1 was not changed. The increase in hepatic CYP1A2, 2B1, and 2E1, and decrease in hepatic CYP2C11 in DMIA rats was returned to the controls by insulin treatment. METHODS. Metformin (100 mg/kg) was administered intravenously and orally to the control rats, DMIA rats, and DMIA rats with insulin treatment for 3 weeks (DMIA rats with insulin). RESULTS. After intravenous administration of metformin to the DMIA rats, the CLR and CLNR of the drug were significantly slower than the controls. After oral administration of metformin to the DMIA rats, the AUC of the drug was also significantly greater than the controls. After intravenous administration of metformin to the DMIA rats with insulin, the significantly slower CLNR of the drug in the DMIA rats was returned to the controls. The altered pharmacokinetic indices observed following intravenous and oral administration of metformin to DMIA rats returned to the control values in the DMIA rats with insulin. CONCLUSIONS. The significantly slower CLNR of metformin in the DMIA rats could be due to the decrease in hepatic CYP2C11 than the controls. The comparable CLNR of metformin between the DMIA rats with insulin and the control rats could be due to restoration of hepatic CYP enzyme changes in DMIA rats to the controls.

Effect of parenchymal shear modulus and lung volume on bronchial pressure-diameter behavior

1978 ◽  
Vol 44 (6) ◽  
pp. 859-868 ◽  
Author(s):  
S. J. Lai-Fook ◽  
R. E. Hyatt ◽  
J. R. Rodarte
Keyword(s):  
Shear Modulus ◽  
Lung Volume ◽  
Pressure Difference ◽  
Transpulmonary Pressure ◽  
Pleural Pressure ◽  
Air Trapping ◽  
Control State ◽  
General Method

A method that interrelates lung pressure-volume behavior, bronchial pressure-diameter behavior, and parenchymal shear modulus is presented. The method was used to predict changes in intraparenchymal bronchial diameter that occurred when lobe pressure-volume behavior and parenchymal shear modulus were markedly changed by inducing air trapping in isolated dog lobes. Predictions agreed with measurements, thereby supporting the general method. Measured values for the shear modulus were approximately 0.7 times the transpulmonary pressure for the control state. Estimated values for the peribronchial pressure difference from pleural pressure during a deflation pressure-volume maneuver for transpulmonary pressures below 12 cmH2O were small, approximately +/- 1 cmH2O, its sign being positive or negative, depending on whether the bronchus was dilated or contricted.

The cartographic ambiguities of HarassMap: Crowdmapping security and sexual violence in Egypt

2015 ◽  
Vol 46 (4) ◽  
pp. 345-364 ◽  
Author(s):  
Nicole Sunday Grove
Keyword(s):  
Sexual Harassment ◽  
Public Space ◽  
Information Technologies ◽  
Open Space ◽  
Spatial Information ◽  
Urban Landscape ◽  
State Violence ◽  
Security Governance ◽  
Crowdsourced Data ◽  
Control State

In December 2010, HarassMap was launched as a Cairo-based interactive online mapping interface for reporting and mapping incidents of sexual harassment anonymously and in real time, in Egypt. The project’s use of spatial information technologies for crowdmapping sexual harassment raises important questions about the use of crowdsourced mapping as a technique of global human security governance, as well as the techno-politics of interpreting and representing spaces of gendered security and insecurity in Egypt’s urban streetscape. By recoding Egypt’s urban landscape into spaces subordinated to the visual cartography of the project’s crowdsourced data, HarassMap obscures the complex assemblage that it draws together as the differentially open space of the Egyptian street – spaces that are territorialized and deterritorialized for authoritarian control, state violence, revolt, rape, new solidarities, gender reversals, sectarian tensions, and class-based mobilization. What is at stake in my analysis is the plasticity of victimage: to what extent can attempts to ‘empower’ women be pursued at the microlevel without amplifying the similarly imperial techniques of objectifying them as resources used to justify other forms of state violence? The question requires taking seriously the practices of mapping and targeting as an interface for securing public space.

Research on automatic irrigation control: State of the art and recent results

2012 ◽  
Vol 114 ◽  
pp. 59-66 ◽  
Author(s):  
R. Romero ◽  
J.L. Muriel ◽  
I. García ◽  
D. Muñoz de la Peña
Keyword(s):  
State Of The Art ◽  
Irrigation Control ◽  
Control State

Glibenclamide attenuates adenosine-induced bradycardia and coronary vasodilatation

1991 ◽  
Vol 261 (3) ◽  
pp. H720-H727 ◽  
Author(s):  
F. L. Belloni ◽  
T. H. Hintze
Keyword(s):  
Heart Rate ◽  
Cardiovascular Responses ◽  
K Channel ◽  
Receptor Blockade ◽  
Beta Adrenergic ◽  
Coronary Vasodilatation ◽  
Cervical Vagotomy ◽  
Adenosine Antagonism ◽  
Anesthetized Dogs ◽  
Control State

The effects of the ATP-sensitive K(+)-channel blocker glibenclamide on the cardiovascular responses to adenosine in dogs were determined. Adenosine (0.01-20 mumol/kg iv) caused coronary vasodilatation, arterial hypotension, and bradycardia in dogs with either combined beta-adrenergic and muscarinic receptor blockade or with bilateral cervical vagotomy plus beta-adrenergic receptor blockade. The 50% effective dose for adenosine-induced coronary dilatation was increased from 0.13 +/- 0.04 mumol/kg in the control state to 1.1 +/- 0.5 mumol/kg after 2 mg/kg of glibenclamide (P less than 0.001). Adenosine at 5 mumol/kg reduced heart rate by 19 +/- 5% from a baseline of 158 +/- 6 beats/min in five anesthetized dogs. After glibenclamide (10 mg/kg), this dose of adenosine failed to cause a significant change in heart rate. The arterial hypotensive effects of adenosine were also attenuated by glibenclamide. Thus glibenclamide inhibited adenosine-induced bradycardia, hypotension, and coronary dilatation. On the other hand, glibenclamide did not affect the reductions in heart rate caused by vagus nerve stimulation. The mechanism of this adenosine antagonism is not known but, in the case of bradycardia, it does not appear to involve any of the steps shared in common by both adenosine-induced and vagal responses of the sinoatrial node.

scholarly journals Differences in liquor prices between control state-operated and license-state retail outlets in the United States

Addiction ◽  
2012 ◽  
Vol 108 (2) ◽  
pp. 339-347 ◽  
Author(s):  
Michael Siegel ◽  
William DeJong ◽  
Alison B. Albers ◽  
Timothy S. Naimi ◽  
David H. Jernigan
Keyword(s):  
United States ◽  
The United States ◽  
Retail Outlets ◽  
Control State
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