An algebraic formula for the output of a system with large-signal, multifrequency excitation

M.B. Steer; P.J. Khan

doi:10.1109/proc.1983.12541

An algebraic formula for the output of a system with large-signal, multifrequency excitation

Proceedings of the IEEE ◽

10.1109/proc.1983.12541 ◽

1983 ◽

Vol 71 (1) ◽

pp. 177-179 ◽

Cited By ~ 26

Author(s):

M.B. Steer ◽

P.J. Khan

Keyword(s):

Large Signal ◽

Algebraic Formula

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An algebraic formula for the output of a system with large-signal multifrequency excitation

Proceedings of the IEEE ◽

10.1109/proc.1983.12730 ◽

1983 ◽

Vol 71 (9) ◽

pp. 1111-1113 ◽

Cited By ~ 1

Author(s):

M.B. Steer ◽

P.J. Khan

Keyword(s):

Large Signal ◽

Algebraic Formula

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Amplifier of Power up to 100 Wt Based on GAN Transistors in Large Signal Mode

Proceedings of Universities ELECTRONICS ◽

10.24151/1561-5405-2020-25-1-78-82 ◽

2020 ◽

Vol 25 (1) ◽

pp. 78-82

Author(s):

V.T. Komarov ◽

Keyword(s):

Large Signal ◽

Signal Mode

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Optimal Duration of the Preincubation Phase in Enzyme Inhibition Experiments

10.26434/chemrxiv.12016974.v1 ◽

2020 ◽

Author(s):

Petr Kuzmic

Keyword(s):

Enzyme Inhibition ◽

Dose Response ◽

Enzyme Inhibitor ◽

Single Point ◽

Association Rate ◽

Weakly Bound ◽

Inhibitor Complex ◽

Dissociation Equilibrium ◽

Optimal Duration ◽

Algebraic Formula

This report describes an algebraic formula to calculate the optimal duration of the pre-incubation phase in enzyme-inhibition experiments, based on the assumed range of expected values for the dissociation equilibrium constant of the enzyme–inhibitor complex and for the bimolecular association rate constant. Three typical experimental scenarios are treated, namely, (1) single-point primary screening at relatively high inhibitor concentrations; (2) dose-response secondary screening of relatively weakly bound inhibitors; (3) dose-response screening of tightly-bound inhibitors.

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