An Investigation of the Potential Benefits in Trading Energy Resolution for Timing Resolution in Time-of-Flight Positron Emission Tomography

2006 ◽  
Author(s):  
Chien-Min Kao ◽  
Dong Yun ◽  
Qingguo Xie ◽  
Chin-Tu Chen
Keyword(s):  
Positron Emission Tomography ◽  
Energy Resolution ◽  
Time Of Flight ◽  
Emission Tomography ◽  
Timing Resolution ◽  
Positron Emission ◽  
Potential Benefits

scholarly journals Evaluation of the PETsys TOFPET2 ASIC in multi-channel coincidence experiments

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Vanessa Nadig ◽  
David Schug ◽  
Bjoern Weissler ◽  
Volkmar Schulz
Keyword(s):  
Positron Emission Tomography ◽  
Integrated Circuits ◽  
Energy Resolution ◽  
Time Of Flight ◽  
Emission Tomography ◽  
Silicon Photomultipliers ◽  
Arrival Times ◽  
Positron Emission ◽  
The Difference ◽  
Tof Pet

Abstract Background Aiming to measure the difference in arrival times of two coincident γ-photons with an accuracy in the order of 200ps, time-of-flight positron emission tomography systems commonly employ silicon photomultipliers (SiPMs) and high-resolution digitization electronics, application specific integrated circuits (ASICs). This work evaluates the performance of the TOFPET2 ASIC, released by PETsys Electronics S.A. in 2017, dependent on its configuration parameters in multi-channel coincidence measurements. Methods SiPM arrays fabricated by different vendors (KETEK, SensL, Hamamatsu, Broadcom) were tested in combination with the ASIC. Scintillator arrays featuring different reflector designs and different configurations of the TOFPET2 ASIC software parameters were evaluated. The benchtop setup used is provided with the TOFPET2 ASIC evaluation kit by PETsys Electronics S.A. Results Compared to existing studies featuring the TOFPET2 ASIC, multi-channel performance results dependent on a larger set of ASIC configuration parameters were obtained that have not been reported to this extend so far. The ASIC shows promising CRTs down to 219.9 ps in combination with two Hamamatsu S14161-3050-HS-08 SiPM arrays (128 channels read out, energy resolution 13.08%) and 216.1 ps in combination with two Broadcom AFBR-S4N44P643S SiPM arrays (32 channels read out, energy resolution 9.46%). The length of the trigger delay of the dark count suppression scheme has an impact on the ASIC performance and can be configured to further improve the coincidence resolution time. The integrator gain configuration has been investigated and allows an absolute improvement of the energy resolution by up to 1% at the cost of the linearity of the energy spectrum. Conclusion Measuring up to the time-of-flight performance of state-of-the-art positron emission tomography (ToF-PET) systems while providing a uniform and stable readout for multiple channels at the same time, the TOFPET2 ASIC is treated as promising candidate for the integration in future ToF-PET systems.

scholarly journals Evaluation of Various Scintillator Materials in Radiation Detector Design for Positron Emission Tomography (PET)

Crystals ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 869
Author(s):  
Siwei Xie ◽  
Xi Zhang ◽  
Yibin Zhang ◽  
Gaoyang Ying ◽  
Qiu Huang ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
High Performance ◽  
Radiation Detector ◽  
Experimental Studies ◽  
Light Output ◽  
Radiation Detectors ◽  
Emission Tomography ◽  
Timing Resolution ◽  
Positron Emission ◽  
Co Doped

The performance of radiation detectors used in positron-emission tomography (PET) is determined by the intrinsic properties of the scintillators, the geometry and surface treatment of the scintillator crystals and the electrical and optical characteristics of the photosensors. Experimental studies were performed to assess the timing resolution and energy resolution of detectors constructed with samples of different scintillator materials (LaBr3, CeBr3, LFS, LSO, LYSO: Ce, Ca and GAGG) that were fabricated into different shapes with various surface treatments. The saturation correction of SiPMs was applied for tested detectors based on a Tracepro simulation. Overall, we tested 28 pairs of different forms of scintillators to determine the one with the best CTR and light output. Two common high-performance silicon photomultipliers (SiPMs) provided by SensL (J-series, 6 mm) or AdvanSiD (NUV, 6 mm) were used for photodetectors. The PET detector constructed with 6 mm CeBr3 cubes achieved the best CTR with a FWHM of 74 ps. The 4 mm co-doped LYSO: Ce, Ca pyramid crystals achieved 88.1 ps FWHM CTR. The 2 mm, 4 mm and 6 mm 0.2% Ce, 0.1% Ca co-doped LYSO cubes achieved 95.6 ps, 106 ps and 129 ps FWHM CTR, respectively. The scintillator crystals with unpolished surfaces had better timing than those with polished surfaces. The timing resolution was also improved by using certain geometric factors, such as a pyramid shape, to improve light transportation in the scintillator crystals.

scholarly journals Time-of-Flight Positron Emission Tomography with Resistive Plate Chamber Detectors: An Unlikely but Promising Approach

2015 ◽  
Vol 127 (5) ◽  
pp. 1453-1461 ◽  
Author(s):  
M. Couceiro ◽  
P. Crespo ◽  
A. Blanco ◽  
N.C. Ferreira ◽  
L. Mendes ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Time Of Flight ◽  
Emission Tomography ◽  
Resistive Plate Chamber ◽  
Positron Emission
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