Evaluation of Spillover and Partial Volume Effect Compensation for Quantitative Accuracy in Cardiac SPECT Perfusion Imaging

2006 ◽  
Author(s):  
P. Hendrik Pretorius ◽  
Michael A. King
Keyword(s):  
Perfusion Imaging ◽  
Volume Effect ◽  
Partial Volume Effect ◽  
Cardiac Spect ◽  
Partial Volume ◽  
Quantitative Accuracy

scholarly journals Development of a New Quantification Method Using Partial Volume Effect Correction for Individual Energy Peaks in 111In-pentetreotide SPECT/CT

2021 ◽  
Author(s):  
Kosuke Yamashita ◽  
Noriaki Miyaji ◽  
Kazuki Motegi ◽  
Takashi Terauchi ◽  
Shigeki Ito
Keyword(s):  
Case Studies ◽  
Quantitative Method ◽  
Volume Effect ◽  
Partial Volume Effect ◽  
Partial Volume ◽  
Quantification Method ◽  
Quantitative Accuracy ◽  
Energy Peak ◽  
The Relationship ◽  
Phantom Experiments

Abstract BackgroundSomatostatin receptor scintigraphy (SRS) using 111In-pentetreotide has no established quantification method. The purpose of this study was to develop a new quantitative method to correct the partial volume effect (PVE) for individual energy peaks in 111In-pentetreotide single-photon emission computed tomography (SPECT). MethodsPhantom experiments were performed to construct a new quantitative method. In the phantom experiments, a NEMA IEC body phantom was used. Acquisition was performed using two energy peaks (171 keV and 245 keV) on the SPECT/CT system. In the SPECT images of each energy peak, the region of interest was set at each hot sphere and lung insert, and the recovery coefficient (RC) was calculated to understand the PVE. A new quantitative index, the indium uptake index (IUI), was calculated using the RC to correct the PVE. The quantitative accuracy of the IUI in the hot sphere was confirmed. Case studies were performed to clarify the quantitative accuracy. In a case study, the relationship between the IUI and the Krenning score, which is used as a visual assessment, was evaluated for each lesion. ResultsThe obtained RCs showed that the energy peak at 171 keV was faster in recovering the effect of PVE than that at 245 keV. The IUI in the 17 mm diameter hot sphere was overestimated by 3.1% at 171 keV and underestimated by 0.5% at 245 keV compared to the actual IUI. In case studies, the relationship between IUI and Krenning score was rs = 0.805 (p < 0.005) at sum, rs = 0.77 (p < 0.005) at 171 keV, and rs = 0.84 (p < 0.005) at 245 keV.Conclusion We have developed a new quantification method for 111In-pentetreotide SPECT/CT using RC-based PVE correction for an individual energy peak of 171 keV. The quantitative accuracy of this method was high even for accumulations of less than 20 mm, and it showed a good relationship with the Krenning score; therefore, the clinical usefulness of IUI was demonstrated.

Partial volume effect of SPECT images in PRRT with 177Lu labelled somatostatin analogues: A practical solution

2019 ◽  
Vol 57 ◽  
pp. 153-159 ◽  
Author(s):  
Domenico Finocchiaro ◽  
Salvatore Berenato ◽  
Elisa Grassi ◽  
Valentina Bertolini ◽  
Gastone Castellani ◽  
...  
Keyword(s):  
Somatostatin Analogues ◽  
Volume Effect ◽  
Partial Volume Effect ◽  
Practical Solution ◽  
Partial Volume ◽  
Spect Images

Spectrum separation resolves partial-volume effect of MRSI as demonstrated on brain tumor scans

2008 ◽  
Vol 21 (10) ◽  
pp. 1030-1042 ◽  
Author(s):  
Yuzhuo Su ◽  
Sunitha B. Thakur ◽  
Karimi Sasan ◽  
Shuyan Du ◽  
Paul Sajda ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Volume Effect ◽  
Partial Volume Effect ◽  
Partial Volume

Segmentation of the skull in MRI volumes using a deformable model and taking the partial volume effect into account

1999 ◽  
Author(s):  
Hilmi Rifai ◽  
Isabelle Bloch ◽  
Seth A. Hutchinson ◽  
Joe Wiart ◽  
Line Garnero
Keyword(s):  
Volume Effect ◽  
Partial Volume Effect ◽  
Deformable Model ◽  
Partial Volume

scholarly journals Ventricle Boundary in CT: Partial Volume Effect and Local Thresholds

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Ihar Volkau ◽  
Fiftarina Puspitasari ◽  
Wieslaw L. Nowinski
Keyword(s):  
Computed Tomography ◽  
Cerebrospinal Fluid ◽  
Grey Matter ◽  
Ground Truth ◽  
Gaussian Mixture ◽  
Volume Effect ◽  
Partial Volume Effect ◽  
Partial Volume ◽  
Image Histogram ◽  
Global Threshold

We present a mathematical frame to carry out segmentation of cerebrospinal fluid (CSF) of ventricular region in computed tomography (CT) images in the presence of partial volume effect (PVE). First, the image histogram is fitted using the Gaussian mixture model (GMM). Analyzing the GMM, we find global threshold based on parameters of distributions for CSF, and for the combined white and grey matter (WGM). The parameters of distribution of PVE pixels on the boundary of ventricles are estimated by using a convolution operator. These parameters are used to calculate local thresholds for boundary pixels by the analysis of contribution of the neighbor pixels intensities into a PVE pixel. The method works even in the case of an almost unimodal histogram; it can be useful to analyze the parameters of PVE in the ground truth provided by the expert.

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