A New Strategy for Handling Global Feedback Loops in Selective-Tracing Waveform Relaxation Algorithm for Large Scale MOSFET Circuit Simulation

Author(s):  
Chun-Jung Chen ◽  
Chun-Chia Chang ◽  
Tai-Ning Yang ◽  
Chih-Jen Lee ◽  
Allen Y. Chang ◽  
...  
2011 ◽  
Vol 383-390 ◽  
pp. 2031-2037
Author(s):  
Chun Jung Chen ◽  
Chih Jen Lee ◽  
Chang Lung Tsai ◽  
Allen Y. Chang ◽  
Tien Hao Shih

In this paper, we propose a modified Waveform Relaxation algorithm to perform large-scale circuit simulation for MOSFET circuits containing lossy coupled transmission lines that have been encountered in modern circuit design community, in which a full time-domain transmission line calculation algorithm based on the Method of Characteristic is adopted. New software techniques are proposed to enhance the robustness as well as efficiency of the simulation process. All proposed methods have been implemented and executed to justify the claimed advantages.


2012 ◽  
Vol 433-440 ◽  
pp. 2837-2843
Author(s):  
Chun Jung Chen ◽  
Chih Jen Lee ◽  
Chang Lung Tsai ◽  
Allen Y. Chang ◽  
Tai Ning Yang ◽  
...  

This paper considers the repeated-executing characteristics of circuit simulators in practical situations, and raises according methods. These methods are incremental simulation and simulation-on-demand (SOD, just simulate the portion of circuit contributing to user-wanted outputs). A specialized relaxation-based algorithm, Backward-traversing Waveform Relaxation (BTWR), is adopted as the fundamental simulation algorithm. All proposed methods have been implemented and tested. Experimental results justify the values of proposed methods.


2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Sun Sook Chung ◽  
Joseph C F Ng ◽  
Anna Laddach ◽  
N Shaun B Thomas ◽  
Franca Fraternali

Abstract Direct drug targeting of mutated proteins in cancer is not always possible and efficacy can be nullified by compensating protein–protein interactions (PPIs). Here, we establish an in silico pipeline to identify specific PPI sub-networks containing mutated proteins as potential targets, which we apply to mutation data of four different leukaemias. Our method is based on extracting cyclic interactions of a small number of proteins topologically and functionally linked in the Protein–Protein Interaction Network (PPIN), which we call short loop network motifs (SLM). We uncover a new property of PPINs named ‘short loop commonality’ to measure indirect PPIs occurring via common SLM interactions. This detects ‘modules’ of PPI networks enriched with annotated biological functions of proteins containing mutation hotspots, exemplified by FLT3 and other receptor tyrosine kinase proteins. We further identify functional dependency or mutual exclusivity of short loop commonality pairs in large-scale cellular CRISPR–Cas9 knockout screening data. Our pipeline provides a new strategy for identifying new therapeutic targets for drug discovery.


VLSI Design ◽  
1999 ◽  
Vol 9 (2) ◽  
pp. 213-218 ◽  
Author(s):  
S. E.-D. Habib ◽  
G. J. Al-Karim

This paper reports the development of the Cairo University Waveform Relaxation (CUWORX) simulator. In order to accelerate the convergence of the waveform relaxation (WR) in the presence of logic feedback, CUWORK is initialized via a logic simulator. This logic initialization scheme is shown to be highly effective for digital synchronous circuits. Additionally, this logic initialization scheme preserves fully the multi-rate properties of the WR algorithm.


Acta Numerica ◽  
2003 ◽  
Vol 12 ◽  
pp. 267-319 ◽  
Author(s):  
Roland W. Freund

In recent years, reduced-order modelling techniques based on Krylov-subspace iterations, especially the Lanczos algorithm and the Arnoldi process, have become popular tools for tackling the large-scale time-invariant linear dynamical systems that arise in the simulation of electronic circuits. This paper reviews the main ideas of reduced-order modelling techniques based on Krylov subspaces and describes some applications of reduced-order modelling in circuit simulation.


Sign in / Sign up

Export Citation Format

Share Document