Multidimensional data integration and relationship inference

2002 ◽  
Vol 17 (2) ◽  
pp. 21-27 ◽  
Author(s):  
Kunbin Qu ◽  
Nan Lin ◽  
Yanmei Lu ◽  
Donald Payan
Author(s):  
Kristian Rother ◽  
Heiko Müller ◽  
Silke Trissl ◽  
Ina Koch ◽  
Thomas Steinke ◽  
...  

BMC Genomics ◽  
2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Le Shu ◽  
Yuqi Zhao ◽  
Zeyneb Kurt ◽  
Sean Geoffrey Byars ◽  
Taru Tukiainen ◽  
...  

2002 ◽  
Vol 17 (2) ◽  
pp. 21-27
Author(s):  
Kunbin Qu ◽  
Nan Lin ◽  
Yanmei Lu ◽  
D.G. Payan

2019 ◽  
Vol 3 (1) ◽  
pp. e201900546
Author(s):  
Matthias Blum ◽  
Pierre-Etienne Cholley ◽  
Valeriya Malysheva ◽  
Samuel Nicaise ◽  
Julien Moehlin ◽  
...  

The enormous amount of freely accessible functional genomics data is an invaluable resource for interrogating the biological function of multiple DNA-interacting players and chromatin modifications by large-scale comparative analyses. However, in practice, interrogating large collections of public data requires major efforts for (i) reprocessing available raw reads, (ii) incorporating quality assessments to exclude artefactual and low-quality data, and (iii) processing data by using high-performance computation. Here, we present qcGenomics, a user-friendly online resource for ultrafast retrieval, visualization, and comparative analysis of tens of thousands of genomics datasets to gain new functional insight from global or focused multidimensional data integration.


2012 ◽  
Vol 9 (2) ◽  
pp. 19-27
Author(s):  
Jia Wei ◽  
Ming Chen

Summary AstraZeneca’s Oncology in vivo data integration platform brings multidimensional data from animal model efficacy, pharmacokinetic and pharmacodynamic data to animal model profiling data and public in vivo studies. Using this platform, scientists can cluster model efficacy and model profiling data together, quickly identify responder profiles and correlate molecular characteristics to pharmacological response. Through meta-analysis, scientists can compare pharmacology between single and combination treatments, between different drug scheduling and administration routes.


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