scholarly journals Micromachined Fiber Optical Sensor for In Vivo Measurement of Optical Properties of Human Skin

2008 ◽  
Vol 8 (10) ◽  
pp. 1698-1703 ◽  
Author(s):  
Alejandro Garcia-Uribe ◽  
Karthik Chinna Balareddy ◽  
Jun Zou ◽  
Lihong V. Wang
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Brett H. Hokr ◽  
Joel N. Bixler

AbstractDynamic, in vivo measurement of the optical properties of biological tissues is still an elusive and critically important problem. Here we develop a technique for inverting a Monte Carlo simulation to extract tissue optical properties from the statistical moments of the spatio-temporal response of the tissue by training a 5-layer fully connected neural network. We demonstrate the accuracy of the method across a very wide parameter space on a single homogeneous layer tissue model and demonstrate that the method is insensitive to parameter selection of the neural network model itself. Finally, we propose an experimental setup capable of measuring the required information in real time in an in vivo environment and demonstrate proof-of-concept level experimental results.


Sensors ◽  
2017 ◽  
Vol 17 (10) ◽  
pp. 2386 ◽  
Author(s):  
Lingjian Meng ◽  
Linbing Wang ◽  
Yue Hou ◽  
Guannan Yan

2000 ◽  
Author(s):  
P. L. Kopsombut ◽  
D. Willis ◽  
A. E. Schen ◽  
L. X. Xu ◽  
X. Xu

Abstract Along with rapid development of diagnostic and therapeutic applications of lasers in medicine, optical properties of various biological tissues have been extensively studied [1]. Most of the studies were performed in vitro owing to the complexity involved in in vivo measurement. To date, it is well understood that living tissue is an absorbing and scattering heterogeneous medium because of its complex structures including blood network. The transport theory cannot be readily used due to the heterogeneity and the absence of the optical properties of living tissues [2]. In this research, we have developed a procedure for measuring the total attenuation coefficient (μ1) of the exteriorized rat 2-D spinotrapezius muscle in the wavelength ranged from 480–560 nm using the collimated light from a Nitrogen-pumped dye laser and a high-sensitivity CCD camera.


2005 ◽  
Vol 43 (10) ◽  
pp. 1159-1166
Author(s):  
Shi Zhiwei ◽  
Zhou Huan ◽  
Li Yang ◽  
Zeng Yanhua

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