High-sensitivity regulated inverter cascode transimpedance amplifier for near infrared spectroscopy

2016 ◽  
Author(s):  
Ahmed Atef ◽  
Mohamed Atef ◽  
Mohamed Abbas ◽  
Elsayed Esam M. Khaled
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
High Sensitivity ◽  
Transimpedance Amplifier

scholarly journals Measurement of Adult Human Brain Responses to Breath-Holding by Multi-Distance Hyperspectral Near-Infrared Spectroscopy

2021 ◽  
Vol 12 (1) ◽  
pp. 371
Author(s):  
Zahida Guerouah ◽  
Steve Lin ◽  
Vladislav Toronov
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
High Sensitivity ◽  
Breath Holding ◽  
Brain Responses ◽  
Adult Humans ◽  
Using Data ◽  
Low Sensitivity ◽  
The Brain

A major limitation of near-infrared spectroscopy (NIRS) is its high sensitivity to the scalp and low sensitivity to the brain of adult humans. In the present work we used multi-distance hyperspectral NIRS (hNIRS) to investigate the optimal source-detector distances, wavelength ranges, and analysis techniques to separate cerebral responses to 30 s breath-holds (BHs) from the responses in the superficial tissue layer in healthy adult humans. We observed significant responses to BHs in the scalp hemodynamics. Cerebral responses to BHs were detected in the cytochrome C oxidase redox (rCCO) at 4 cm without using data from the short-distance channel. Using the data from the 1 cm channel in the two-layer regression algorithm showed that cerebral hemodynamic and rCCO responses also occurred at 3 cm. We found that the waveband 700–900 nm was optimal for the detection of cerebral responses to BHs in adults.

scholarly journals Measurement of Adult Human Brain Responses to Breath Holding by Multi-Distance Hyperspectral Near-Infrared Spectroscopy

2021 ◽  
Author(s):  
Zahida Guerouah ◽  
Steve Lin ◽  
Vladislav Toronov
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
High Sensitivity ◽  
Breath Holding ◽  
Brain Responses ◽  
Adult Humans ◽  
Using Data ◽  
Low Sensitivity ◽  
The Brain

A major limitation of near-infrared spectroscopy (NIRS) is its high sensitivity to the scalp and low sensitivity to the brain of adult humans. In the present work we use multi-distance hyperspectral NIRS (hNIRS) to investigate the optimal source-detector distances, range of wavelengths, and analysis techniques to separate cerebral responses to 30-s breath holds (BHs) from the responses in the superficial tissue layer in healthy adult humans. We observed significant responses to BHs in the scalp hemodynamics. Cerebral responses to BHs were detected in the cytochrome C oxidase redox (rCCO) at 4 cm without using data from the short-distance channel. Using the data from the 1 cm channel in the two-layer regression algorithm showed that hemodynamic and rCCO responses also occurred at 3cm. We found that the waveband 700-900 nm was optimal for the detection of cerebral responses to BHs in adults.

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