Biomechanical and in vivo comparison of three fixation devices for the long lasting maintenance of a critical size bone defect in the rat femur — A proposed model for segmental bone defect research

2011 ◽  
Author(s):  
George I. Mataliotakis ◽  
Simeon Agathopoulos ◽  
Marios D. Vekris ◽  
Grigorios I. Mitsionis
Keyword(s):  
Bone Defect ◽  
Critical Size ◽  
Rat Femur ◽  
Segmental Bone Defect ◽  
Proposed Model ◽  
Fixation Devices ◽  
Segmental Bone

scholarly journals Determining the critical size of a rabbit rib segmental bone defect model

2016 ◽  
Vol 3 (5) ◽  
pp. 323-328 ◽  
Author(s):  
Fengzhen Liu ◽  
Kun Chen ◽  
Lei Hou ◽  
Keyi Li ◽  
Dawei Wang ◽  
...  
Keyword(s):  
Bone Defect ◽  
Critical Size ◽  
Segmental Bone Defect ◽  
Defect Model ◽  
Segmental Bone

Bilayer nanostructure coated AZ31 magnesium alloy implants: in vivo reconstruction of critical-sized rabbit femoral segmental bone defect

2020 ◽  
Vol 29 ◽  
pp. 102232
Author(s):  
Govindaraj Perumal ◽  
Boopalan Ramasamy ◽  
Maya Nandkumar A ◽  
Sivaraman Dhanasekaran ◽  
Selvaraj Ramasamy ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Bone Defect ◽  
Az31 Magnesium Alloy ◽  
Segmental Bone Defect ◽  
Segmental Bone

Fabrication of piezoelectric porous BaTiO3 scaffold to repair large segmental bone defect in sheep

2020 ◽  
Vol 35 (4-5) ◽  
pp. 544-552 ◽  
Author(s):  
Wenwen Liu ◽  
Di Yang ◽  
Xinghui Wei ◽  
Shuo Guo ◽  
Ning Wang ◽  
...  
Keyword(s):  
Electric Field ◽  
Bone Defect ◽  
Piezoelectric Effect ◽  
Bone Defects ◽  
Segmental Bone Defect ◽  
Segmental Bone ◽  
Large Bone ◽  
Large Bone Defects

Porous titanium scaffolds can provide sufficient mechanical support and bone growth space for large segmental bone defect repair. However, they fail to restore the physiological environment of bone tissue. Barium titanate (BaTiO3) is considered a smart material that can produce an electric field in response to dynamic force. Low-intensity pulsed ultrasound stimulation (LIPUS), as a kind of micromechanical wave, can not only promote bone repair but also induce BaTiO3 to generate an electric field. In our studies, BaTiO3 was coated on porous Ti6Al4V and LIPUS was externally applied to observe the influence of the piezoelectric effect on the repair of large bone defects in vitro and in vivo. The results show that the piezoelectric effect can effectively promote the osteogenic differentiation of bone marrow stromal cells (BMSCs) in vitro as well as bone formation and growth into implants in vivo. This study provides an optional alternative to the conventional porous Ti6Al4V scaffold with enhanced osteogenesis and osseointegration for the repair of large bone defects.

Early weight bearing of porous HA/TCP (60/40) ceramics in vivo: A longitudinal study in a segmental bone defect model of rabbit

2007 ◽  
Vol 3 (6) ◽  
pp. 985-996 ◽  
Author(s):  
Cenk Balçik ◽  
Turgut Tokdemir ◽  
Alpaslan Şenköylü ◽  
Nurşen Koç ◽  
Muharrem Timuçin ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Bone Defect ◽  
Weight Bearing ◽  
Segmental Bone Defect ◽  
Defect Model ◽  
Early Weight Bearing ◽  
Segmental Bone
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