Quantification of the hemodynamics inside a novel Synchronized Therapeutic Cardiac Assist Device for Chronic Heart Failure

Author(s):  
Sara Naftali ◽  
Idit Avrahami ◽  
Amir Landesberg
2006 ◽  
Vol 81 (5) ◽  
pp. 1738-1744 ◽  
Author(s):  
Ralph J. Petrucci ◽  
Karen C. Truesdell ◽  
Anne Carter ◽  
Naomi E. Goldstein ◽  
Megan M. Russell ◽  
...  

Author(s):  
Nigel R. Schneider ◽  
Jason Cecchetti ◽  
Yi Wu

Numerical simulations are important tools for understanding the human circulation system in different states of heart failure and exercise, or with a cardiac assist device. However, its application is limited due to the complexity of the numerical model of the human circulation system. To overcome this difficulty, a Graphic User Interface (GUI) has been developed. The GUI was designed to be intuitive; users can set different scenarios using self-explanatory controls, without knowledge of the tasks done in the complex numerical model. The GUI will display the simulated hemodynamic response of the model. This GUI may be used for both education and medical/research purposes.


2015 ◽  
Vol 156 (13) ◽  
pp. 521-527
Author(s):  
Levente Fazekas ◽  
Balázs Sax ◽  
István Hartyánszky ◽  
Miklós Pólos ◽  
Ferenc Horkay ◽  
...  

Introduction: Since the celebration of the 20th anniversary of the first heart transplantation in Hungary in 2012 the emerging need for modern heart failure management via mechanical circulatory support has evolved. In May 2012 the opening of a new heart failure and transplant unit with 9 beds together with the procurement of necessary devices at Semmelweis University accomplished this need. Aim: The aim of the authors was to report their initial experience obtained in this new cardiac assist device program. Method: Since May, 2012, mechanical circulatory support system was applied in 89 cases in 72 patients. Indication for support were end stage heart failure refractory to medical treatment and acute left or right heart failure. Results: Treatment was initiated for acute graft failure after heart transplantation in 27 cases, for end stage heart failure in 24 cases, for acute myocardial infarction in 21 cases, for acute postcardiotomy heart failure in 14 cases, for severe respiratory insufficiency in 2 cases and for drug intoxication in one case. Among the 30 survivor of the whole program 13 patients were successfully transplanted. Conclusions: The available devices can cover all modalities of current bridge therapy from short term support through medium support to heart transplantation or long term support and destination therapy. These conditions made possible the successful start of a new cardiac assist device program. Orv. Hetil., 2015, 156(13), 521–527.


1990 ◽  
Vol 112 (1) ◽  
pp. 75-79 ◽  
Author(s):  
O. Lichtenstein ◽  
U. Dinnar

This study presents a simulated analysis of Phased Compression Cardiac Assist Device (PCCAD) and evaluation of its applicability as a non-invasive temporary assist for a failing heart. The new technique is based on the chest pump mechanism for blood flow augmentation during external massage by phased compression of the abdominal and thoracic cavities. A semi-closed hydraulic system to simulate the systemic circulation was constructed; the system includes a left ventricle which functions according to the Starling principle and a pneumatic system which controls the pressures applied to the thoracic and abdominal cavities, in complete synchronization with the beating normal or failing heart. The possibility of manipulating the three pumps in series (venous, heart, and arterial) has been checked, and the principal parameters which effect the efficiency of the PCCAD were evaluated. This in-vitro analysis shows the high potential of a non-invasive temporary cardiac assist device. It points to the necessary measures one has to take in order to achieve good synchronization and to interfere externally with the augmentation of cardiac output or with the augmentation of root aortic pressure.


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