Intelligent Techniques Analysis for Glycosylation Site Prediction

2021 ◽  
Vol 15 ◽  
Author(s):  
Alhassan Alkuhlani ◽  
Walaa Gad ◽  
Mohamed Roushdy ◽  
Abdel-Badeeh M. Salem
Keyword(s):  
Machine Learning ◽  
Prediction Models ◽  
Cell Interaction ◽  
Glycosylation Site ◽  
Machine Learning Classification ◽  
Site Prediction ◽  
Glycosylation Sites ◽  
Wide Range ◽  
Feature Extraction And Selection ◽  
Computational Intelligent

Background: Glycosylation is one of the most common post-translation modifications (PTMs) in organism cells. It plays important roles in several biological processes including cell-cell interaction, protein folding, antigen’s recognition, and immune response. In addition, glycosylation is associated with many human diseases such as cancer, diabetes and coronaviruses. The experimental techniques for identifying glycosylation sites are time-consuming, extensive laboratory work, and expensive. Therefore, computational intelligence techniques are becoming very important for glycosylation site prediction. Objective: This paper is a theoretical discussion of the technical aspects of the biotechnological (e.g., using artificial intelligence and machine learning) to digital bioinformatics research and intelligent biocomputing. The computational intelligent techniques have shown efficient results for predicting N-linked, O-linked and C-linked glycosylation sites. In the last two decades, many studies have been conducted for glycosylation site prediction using these techniques. In this paper, we analyze and compare a wide range of intelligent techniques of these studies from multiple aspects. The current challenges and difficulties facing the software developers and knowledge engineers for predicting glycosylation sites are also included. Method: The comparison between these different studies is introduced including many criteria such as databases, feature extraction and selection, machine learning classification methods, evaluation measures and the performance results. Results and conclusions: Many challenges and problems are presented. Consequently, more efforts are needed to get more accurate prediction models for the three basic types of glycosylation sites.

Intelligent Diagnostics for Ball Screw Fault Through Indirect Sensing Using Deep Domain Adaptation

2021 ◽  
Vol 70 ◽  
pp. 1-11
Author(s):  
Vibhor Pandhare ◽  
Xiang Li ◽  
Marcella Miller ◽  
Xiaodong Jia ◽  
Jay Lee
Keyword(s):  
Domain Adaptation ◽  
Ball Screw ◽  
Intelligent Diagnostics

Hybrid Computational Intelligence and the Basic Concepts and Recent Advances

2018 ◽  
pp. 180-190
Author(s):  
Georgios Dounias
Keyword(s):  
Computational Intelligence ◽  
Intelligent Systems ◽  
Domain Knowledge ◽  
Hybrid Intelligent Systems ◽  
Complex Problems ◽  
Recent Advances ◽  
New Findings ◽  
Wide Range ◽  
Computational Intelligent ◽  
Computational Technology

In this paper computational intelligence and its major methodologies are introduced in the first place, and then hybrid intelligent systems are defined and the most popular hybrid intelligent approaches are discussed. The increased popularity of hybrid intelligent systems during the last decade, is the result of the extensive success of these systems in a wide range of real-world complex problems, but also has to do with the increased capabilities of computational technology. One of the reasons for this success has to do with the synergy derived by the computational intelligent components, such as machine learning, fuzzy logic, neural networks, genetic algorithms, or other intelligent algorithms and techniques. Each of the partial methodologies provides hybrid systems with complementary reasoning and searching methods that allow the use of domain knowledge and empirical data to solve complex problems. The paper includes recent advances and new findings in the area of hybrid computational intelligence.

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