2D Electro-Optical Trapping and Analysis of Single Particles on an Integrated Optofluidic Chip

Author(s):  
M. Rahman ◽  
M. A. Stott ◽  
Y. Li ◽  
A. R. Hawkins ◽  
H. Schmidt
Optica ◽  
2019 ◽  
Vol 6 (9) ◽  
pp. 1130 ◽  
Author(s):  
M. Rahman ◽  
M. Harrington ◽  
M. A. Stott ◽  
Y. Li ◽  
M. J. N. Sampad ◽  
...  

Lab on a Chip ◽  
2010 ◽  
Vol 10 (2) ◽  
pp. 189-194 ◽  
Author(s):  
S. Kühn ◽  
B. S. Phillips ◽  
E. J. Lunt ◽  
A. R. Hawkins ◽  
H. Schmidt

2017 ◽  
Vol 23 (2) ◽  
pp. 176-184 ◽  
Author(s):  
Diane De Coster ◽  
Qing Liu ◽  
Michael Vervaeke ◽  
Jurgen Van Erps ◽  
Jeroen Missinne ◽  
...  

Author(s):  
S. Cusack ◽  
J.-C. Jésior

Three-dimensional reconstruction techniques using electron microscopy have been principally developed for application to 2-D arrays (i.e. monolayers) of biological molecules and symmetrical single particles (e.g. helical viruses). However many biological molecules that crystallise form multilayered microcrystals which are unsuitable for study by either the standard methods of 3-D reconstruction or, because of their size, by X-ray crystallography. The grid sectioning technique enables a number of different projections of such microcrystals to be obtained in well defined directions (e.g. parallel to crystal axes) and poses the problem of how best these projections can be used to reconstruct the packing and shape of the molecules forming the microcrystal.Given sufficient projections there may be enough information to do a crystallographic reconstruction in Fourier space. We however have considered the situation where only a limited number of projections are available, as for example in the case of catalase platelets where three orthogonal and two diagonal projections have been obtained (Fig. 1).


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