Bayesian analysis for parameter estimation for use in PSA - a case study

Author(s):  
M. Hari Prasad ◽  
V. V. S. Sanyasi Rao ◽  
A. K. Verma ◽  
A. Srividya
1997 ◽  
Vol 30 (6) ◽  
pp. 1563-1568
Author(s):  
Vincent G. Ryckaert ◽  
Jan F. Van Impe
Keyword(s):  

2018 ◽  
Vol 95 (3) ◽  
pp. 463-483 ◽  
Author(s):  
Jiansong Wu ◽  
Weipeng Fang ◽  
Xing Tong ◽  
Shuaiqi Yuan ◽  
Weiqi Guo

2018 ◽  
Vol 11 ◽  
pp. 210-217 ◽  
Author(s):  
A. De Falco ◽  
M. Girardi ◽  
D. Pellegrini ◽  
L. Robol ◽  
G. Sevieri

2010 ◽  
Vol 7 (3) ◽  
Author(s):  
Syed Murtuza Baker ◽  
Kai Schallau ◽  
Björn H. Junker

SummaryComputational models in systems biology are usually characterized by a lack of reliable parameter values. This is especially true for kinetic metabolic models. Experimental data can be used to estimate these missing parameters. Different optimization techniques have been explored to solve this challenging task but none has proved to be superior to the other. In this paper we review the problem of parameter estimation in kinetic models. We focus on the suitability of four commonly used optimization techniques of parameter estimation in biochemical pathways and make a comparison between those methods. The suitability of each technique is evaluated based on the ability of converging to a solution within a reasonable amount of time. As most local optimization methods fail to arrive at a satisfactory solution we only considered the global optimization techniques. A case study of the upper part of Glycolysis consisting 15 parameters is taken as the benchmark model for evaluating these methods.


1977 ◽  
Vol 4 (4) ◽  
pp. 462-470 ◽  
Author(s):  
Thomas W. Constable ◽  
Edward A. McBean

Two nonlinear parameter estimation techniques are used to obtain expected values, variances, and covariance estimates for L and k in the first-order BOD equation. The techniques are compared with a number of other BOD parameter estimation methods with respect to both estimated values of L and k and necessary assumptions about the measurement error structure of BOD analyses. The techniques that historically have been used to estimate the parameters in the first-order BOD equation are shown to often give erroneous answers because of their use of an incorrect error structure.A case study application of the methodology to the raw influent and primary effluent of the Waterloo Pollution Control Plant is included.


2012 ◽  
Vol 8 (S295) ◽  
pp. 312-312
Author(s):  
Yunkun Han ◽  
Zhanwen Han

AbstractIn Han & Han (2012), we have preliminarily built BayeSED and applied it to a sample of hyperluminous infrared galaxies. The physically reasonable results obtained from Bayesian model comparison and parameter estimation show that BayeSED could be a useful tool for understanding the nature of complex systems, such as dust obscured starburst-AGN composite galaxies, from decoding their complex SEDs. In this contribution, we present a more rigorous test of BayeSED by making a mock catalog from model SEDs with the value of all parameters to be known in advance.


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