Data Signature-Based Multiyear Analysis of BLK-NB 6-Minute Interval Datasets of 2006 to 2009

2012 ◽  
Author(s):  
J. C. Villena ◽  
J. A. Malinao ◽  
H. N. Adorna
Keyword(s):  
Minute Interval

Pregabalin As A Premedicant To Attenuate Pressor Response In Patients Undergoing Laparoscopic Cholecystectomy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study

2020 ◽  
Vol 11 (3) ◽  
pp. 3418-3423
Author(s):  
Sweety Agrawal ◽  
Shubdha Bhagat ◽  
Pratibha Deshmukh ◽  
Amol Singham
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Pressor Response ◽  
Controlled Study ◽  
Double Blind ◽  
Co2 Insufflation ◽  
Ramsay Sedation Scale ◽  
Minute Interval ◽  
Group A ◽  
Group B ◽  
Induction Of Anaesthesia

The present study was done to evaluate the ability of oral pregabalin to attenuate the pressor response to airway instrumentation in patients undergoing laparoscopic cholecystectomy under general anesthesia. Sixty-four adult patients aged between 25-55 year of either gender belonging to ASA-1 or ASA2 physical status weighing 50-70 kg were enrolled in this study. Thirty-two patients each were randomized to group A, or group B. Patients in group A received tablet Pregabalin (150mg) and those in group B received placebo orally one hour before induction of anaesthesia. Heart rate, blood pressure, and sedation were assessed preoperatively before giving the tablets and after 30 minutes, and just before induction of anaesthesia. Intraoperative, pulse rate, mean arterial pressure, ECG in the lead II, SPO2 and ETCO2 were monitored. All the above parameters were noted during laryngoscopy and intubation, 3 minutes after CO2 insufflation, and then at every 10-minute interval till the end of surgery. These parameters were also recorded after extubating the patient. The Ramsay sedation scale was used to assess the sedation at the baseline, one hour after drug intake , one hour after extubation and 4 hour after surgery. Any adverse effects in the postoperative period were recorded. The result of our study shows that pre-emptive administration of oral pregabalin 150 mg significantly reduced the pressor response at the time of laryngoscopy and intubation, after CO2 insufflation and just after extubation. We conclude that oral pregabalin premedication is effective in successful attenuation of hemodynamic pressor response to laryngoscopy, intubation and pneumoperitoneum in patients undergoing laparoscopic cholecystectomy

Abstract P124: Repeat Manual Office Blood Pressure By A Physician Is Lower Than Automated Office Blood Pressure

Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Bryce Rhodehouse ◽  
Courtney Shaver ◽  
Jerry Fan ◽  
Bright Izekor ◽  
Clinton Jones ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vital Signs ◽  
Outpatient Setting ◽  
Office Blood Pressure ◽  
P Value ◽  
Signed Rank ◽  
Significant Difference ◽  
Minute Interval ◽  
The Difference ◽  
Automated Office Blood Pressure

Introduction: An accurate measurement of blood pressure (BP) is critical to diagnosing and treating hypertension (HTN). Manual office BP (MOBP) often results in higher readings than automated office BP (AOBP). In previous studies, a repeat MOBP by a physician resulted in a lower BP than the initial MOBP by nursing staff. We evaluated our hypothesis that a repeat MOBP by a physician is statistically equivalent to AOBP. Methods: In an ambulatory outpatient setting, patients were roomed and at least a 5-minute interval lapsed before an AOBP was performed using a Welch Allyn Connex Vital Signs Monitor. The physician was blinded to the AOBP. The physician then entered the room and obtained a MOBP with a manual aneroid sphygmomanometer. The difference between the AOBP and the MOBP was calculated. A Wilcoxon signed rank sum test was used to determine if a significant difference between AOBP and MOBP exists. Results: A total of 186 patients (112 females, 74 male) had BP measured with a mean age of 66 years. AOBP resulted in a median systolic BP (SBP) 136 mmHg (IQR 121-150 mmHg) and median diastolic BP (DBP) of 78 mmHg (IQR 72-85 mmHg). MOBP SBP had a median of 132 mmHg (IQR 120-142 mmHg) and DBP had a median of 76 mmHg (IQR 70-81 mmHg). SBP and DBP were significantly lower in the MOBP group with a mean difference between AOBP and MOBP of 4.0 and 2.7 mmHg respectively (p-value of <0.0001). Conclusions: Repeat MOBP performed by the physician resulted in a significantly lower BP compared to AOBP. The lower BP may be due to an overall longer interval between the AOBP measurement and MOBP measurement. MOBP may be a viable option for accurate diagnosis and treatment of HTN clinics without access to a AOBP machine.

scholarly journals Pre-Release Assessment for Javan Gibbon (Hylobates moloch) in The Javan Gibbon Center, Mount Gede Pangrango National Park

2019 ◽  
Vol 11 (1) ◽  
pp. 15-24
Author(s):  
Anton Ario ◽  
Agus Priyono Kartono ◽  
Lilik Budi Prasetyo ◽  
Jatna Supriatna
Keyword(s):  
National Park ◽  
Sampling Method ◽  
Readiness Assessment ◽  
Recording Time ◽  
Assessment Study ◽  
Focal Animal ◽  
Hylobates Moloch ◽  
Minute Interval ◽  
Release Data ◽  
Javan Gibbon

Preparation for gibbons before being released into their habitat is crucial. Thus, there is a need for readiness assessment of Javan gibbon with several criteria derived from other species of gibbons to determine individual readiness. Pre-release assessment study for Javan gibbon (Hylobates moloch) had been conducted in January – February 2014, November – December 2014, and March-April 2016 in the Javan Gibbon Center, Mount Gede Pangrango National Park, West Java, Indonesia. The objective of this research was to assess the readiness of Javan gibbon behavior prior to release. Data collection was conducted by focal animal sampling method with 5-minute interval recording time and ad libitum method. The average time allocations of Javan Gibbon activities were as follow: feeding (18.17±3.34%); moving (22.34±0.53%); resting (46.24±3.84%); socializing (10.13±4.33%); sexual activity (0.59±0.58%); and vocalizing (2.54±0.88%).  The similarities of activity allocation from this study compared by wild Javan gibbons data found as follows: feeding by 33.03%, moving by 90.97%, resting by 61.52%, socializing by 38.09%, vocalizing by 75.02%, and sexual by 44.24%. Based on readiness assessment of 11 Javan gibbons, 3 individuals were considered almost ready for release, while 8 individuals were considered ready. The assessment of behaviors criteria for the readiness of Javan gibbons before release has not existed before. The results of this research are important as a recommendation for the management of wildlife rehabilitation and as a guideline in implementing the rehabilitation and reintroduction program of Javan gibbons.

scholarly journals 684. Cardiac Safety in Adults with Community-Acquired Bacterial Pneumonia (CABP) Treated with Lefamulin (LEF) or Moxifloxacin (MOX): Analysis of Lefamulin Evaluation Against Pneumonia (LEAP) 1 and LEAP 2 Study Results

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S311-S311
Author(s):  
Borje Darpo ◽  
Anita F Das ◽  
Daniel Stein ◽  
Jennifer Schranz ◽  
Steven P Gelone
Keyword(s):  
Torsade De Pointes ◽  
Significant Risk ◽  
Study Drug ◽  
Qt Prolongation ◽  
Drug Discontinuation ◽  
Cardiac Safety ◽  
Study Results ◽  
Minute Interval ◽  
Clinically Significant ◽  
Study Drug Discontinuation

Abstract Background Preclinical data suggest potential effects of LEF on cardiac interval parameters. We therefore assessed LEF cardiac safety from the LEAP 1/2 trials. Methods In LEAP 1, PORT III–V patients received LEF 150mg IV q12h for 5–7 days or MOX 400mg IV q24h for 7 days, with optional IV-to-oral switch (600mg LEF q12h or 400 mg MOX q24h). In LEAP 2, PORT II–IV patients received oral LEF 600mg q12h for 5 days or oral MOX 400mg q24h for 7 days. Patients with known QT prolongation or on medication with potential to prolong the QT interval were excluded as per MOX label. After 5 minutes of rest in the supine position, triplicate 12-lead ECGs were obtained within a 5-minute interval at Screening in both studies, on Days 1/3 in LEAP 1 (predose and ≤15 minutes after first IV dose), and on Days 1/4 in LEAP 2 (predose and 1–3 hours after first oral dose), and sent to a central ECG reader for adjudication. Results Of 1,282 randomized/treated patients (n = 641/group), 1,274 had baseline (BL) and post-BL ECG data (n = 636 LEF, n = 638 MOX). Consistent with the resolution of infection, ECGs revealed mean reductions of 7–8 beats/minute for both groups in both studies. The largest mean change in QTcF from BL to post-BL was on Day 3 in LEAP 1 (13.6 and 16.4 msec with IV LEF and MOX, respectively) and on Day 4 in LEAP 2 (9.3 and 11.6 msec with oral LEF and MOX, respectively). The proportion of patients meeting potentially important post-BL QTcF values/changes was comparable between treatment groups (table). In the standardized MedDRA query of Torsade de pointes/QT prolongation (broad), the most common treatment-emergent adverse event was ECG QT prolonged (n = 4 LEF, n = 5 MOX). All events were nonserious and mild or moderate in severity. 6 events were considered study drug related (n = 4 LEF, n = 2 MOX). 5 events led to study drug discontinuation (n = 2 LEF, n = 3 MOX). In 2 patients with cardiovascular disease, 1 had ventricular arrhythmia on Day 20 (18 days after last LEF dose) and 1 had cardiac arrest on Day 18 (9 days after last MOX dose); both events were fatal and considered unrelated to study drug by investigator. Conclusion Mild prolongation of the QTcF interval was seen with LEF and MOX, with somewhat smaller effects seen with LEF. Given the small effect, LEF is unlikely to pose a clinically significant risk of ventricular proarrhythmia with appropriate precautions and use. Disclosures All authors: No reported disclosures.

A Cross-Over Trial Comparing Conventional to Compression-Adjusted Ventilations with Metronome-Guided Compressions

2019 ◽  
Vol 34 (02) ◽  
pp. 220-223 ◽  
Author(s):  
Dhimitri A. Nikolla ◽  
Brandon J. Kramer ◽  
Jestin N. Carlson
Keyword(s):  
Cardiac Arrest ◽  
Cardiopulmonary Resuscitation ◽  
Null Hypothesis ◽  
Basic Life Support ◽  
Life Support ◽  
Minute Ventilation ◽  
Group Versus ◽  
Time Intervals ◽  
Minute Interval ◽  
Ventilation Rates

Introduction:Hyperventilation during cardiopulmonary resuscitation (CPR) negatively affects cardiopulmonary physiology. Compression-adjusted ventilations (CAVs) may allow providers to deliver ventilation rates more consistently than conventional ventilations (CVs). This study sought to compare ventilation rates between these two methods during simulated cardiac arrest.Null Hypothesis:That CAV will not result in different rates than CV in simulated CPR with metronome-guided compressions.Methods:Volunteer Basic Life Support (BLS)-trained providers delivered bag-valve-mask (BVM) ventilations during simulated CPR with metronome-guided compressions at 100 beats/minute. For the first 4-minute interval, volunteers delivered CV. Volunteers were then instructed on how to perform CAV by delivering one breath, counting 12 compressions, and then delivering a subsequent breath. They then performed CAV for the second 4-minute interval. Ventilation rates were manually recorded. Minute-by-minute ventilation rates were compared between the techniques.Results:A total of 23 volunteers were enrolled with a median age of 36 years old and with a median of 14 years of experience. Median ventilation rates were consistently higher in the CV group versus the CAV group across all 1-minute segments: 13 vs 9, 12 vs 8, 12 vs 8, and 12 vs 8 for minutes one through four, respectively (P &lt;.01, all). Hyperventilation (&gt;10 breaths per minute) occurred 64% of the time intervals with CV versus one percent with CAV (P &lt;.01). The proportion of time which hyperventilation occurred was also consistently higher in the CV group versus the CAV group across all 1-minute segments: 78% vs 4%, 61% vs 0%, 57% vs 0%, and 61% vs 0% for minutes one through four, respectively (P &lt;.01, all).Conclusions:In this simulated model of cardiac arrest, CAV had more accurate ventilation rates and fewer episodes of hyperventilation compared with CV.Nikolla DA, Kramer BJ, Carlson JN. A cross-over trial comparing conventional to compression-adjusted ventilations with metronome-guided compressions. Prehosp Disaster Med. 2019;34(2):220–223

scholarly journals Employees’ Exposure to Carbon Monoxide in Pakistan Steel Mills

2014 ◽  
Vol 3 (4) ◽  
pp. 44-56
Author(s):  
Kanza Abid ◽  
Zafar Iqbal Shams
Keyword(s):  
Carbon Monoxide ◽  
Raw Materials ◽  
Carbon Monoxide Poisoning ◽  
Production Plant ◽  
Iron And Steel ◽  
Steel Mills ◽  
Steel Making ◽  
Minute Interval ◽  
Elevated Exposure ◽  
Mean Concentration

Many processes in the iron and steel making industries emit carbon monoxide, which causes a variety of toxic effects on human health, such as fatigue, impaired memory, headache, and nausea. At elevated exposure, carbon monoxide poisoning may lead to loss of consciousness and death. Therefore, the current study has been carried out to investigate the occupational exposure of randomly selected fifty-eight employees of Pakistan Steel Mills to the carbon monoxide. The selected employees were from 10 different facilities of the Pakistan Steel Mills, who were working in two different shifts viz. nightshift and dayshift, each of twelve hours. Thirty employees from nightshift and twenty-eight employees from dayshift were monitored for their exposure to carbon monoxide. The instrument was logged to measure the employee’s exposure to carbon monoxide with 1-minute interval. The study reveals that the employees, working in the Raw Materials Production Plant during nightshift were exposed to the highest mean concentration of carbon monoxide while those working in Oxygen Plant during nightshift were exposed to the lowest mean concentration of carbon monoxide. According to study, the highest recorded exposure was found near Blast Furnace during dayshift. The employees’ exposure to 98th percentile concentration of carbon monoxide in different facilities of the steel mills has also been analyzed. The employees’ exposure to carbon monoxide during commuting from home to their workplace has also been investigated.DOI: http://dx.doi.org/10.3126/ije.v3i4.11730      International Journal of EnvironmentVolume-3, Issue-4, Sep-Nov 2014Page: 44-56

scholarly journals How Is the Intensity of Rainfall Events Best Characterised? A Brief Critical Review and Proposed New Rainfall Intensity Index for Application in the Study of Landsurface Processes

Water ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 929 ◽  
Author(s):  
David Dunkerley
Keyword(s):  
Rainfall Intensity ◽  
Clock Period ◽  
Event Duration ◽  
Rainfall Events ◽  
Rainfall Characteristics ◽  
Convective Storms ◽  
Intensity Index ◽  
Rainfall Depth ◽  
Minute Interval ◽  
Event Based

In many studies of landsurface processes, the intensity of rainfall events is expressed with clock-period indexes such as I30, the wettest 30-minute interval within a rainfall event. Problematically, the value of I30 cannot be estimated for rainfall events shorter than 30 min, excluding many intense convective storms. Further, it represents a diminishing proportion of increasingly long rainfall events, declining to <2% of the duration of a 30-hour event but representing 25% of the duration of a two-hour event. Here, a new index termed EDf5 is proposed: It is the rainfall depth in the wettest 5% of the event duration. This can be derived for events of any duration. Exploratory determinations of EDf5 are presented for two Australian locations with contrasting rainfall climatologies—one arid and one wet tropical. The I30 index was similar at both sites (7.7 and 7.9 mm h−1) and was unable to differentiate between them. In contrast, EDf5 at the arid site was 7.4 mm h−1, whilst at the wet tropical site, it was 3.8 mm h−1. Thus, the EDf5 index indicated a greater concentration of rain at the arid site where convective storms occurred (i.e., the intensity sustained for 5% of event duration at that site is higher). The EDf5 index can be applied to short, intense events that can readily be included in the analysis of event-based rainfall intensity. I30 therefore appears to offer less discriminatory power and consequently may be of less value in the investigation of rainfall characteristics that drive many important landsurface processes.

scholarly journals Earth based observations of solar luminosity oscillations

1988 ◽  
Vol 123 ◽  
pp. 71-74
Author(s):  
A. Jiménez ◽  
P.L. Pallé ◽  
F. Pérez Hernández ◽  
C. Régulo ◽  
T. Roca Cortés ◽  
...  
Keyword(s):  
Power Spectra ◽  
Solar Oscillations ◽  
Solar Luminosity ◽  
Peak Identification ◽  
Minute Interval

Earth based multichannel photometry of integral sunlight has been obtained at Izaña (Tenerife) during 1984–1986. Power spectra of the solar luminosity variations of individual days show power in the 5 minute interval above noise at a level comparable to SMM datad). When combining contigous days of data the signature of p mode solar oscillations spectrum appears* although individual peak identification is difficult.

Rural Perinatal Loss: A Needs Assessment

2020 ◽  
pp. 003022282092629
Author(s):  
Julie S. Domogalla ◽  
Janet McCord ◽  
Rebecca Morse
Keyword(s):  
Perinatal Loss ◽  
Phenomenological Approach ◽  
East Central ◽  
Continuing Bond ◽  
Minute Interval ◽  
Mother And Child ◽  
Infant Loss ◽  
Childhood Loss ◽  
Nonprobability Sample ◽  
Bereavement Care

The purpose of this research was to ascertain the availability and depth of services of bereavement care for mothers who live rurally. The specific focus is on those who experienced early losses including pregnancy, stillbirth, neonatal, and young children who were born with fetal anomalies or neonatal disease that resulted in death. The convenience (nonprobability) sample originated from a population of mothers who lived in rural east central Minnesota. Participants were interviewed in a 60-minute interval. All data were coded confidential. Common themes, incidence of resources, or lack of bereavement resources for the participants’ lived experiences were considered using a descriptive phenomenological approach. Our appreciation of the continuing bond between mother and child compels us to believe that there is an ethical obligation to reduce and remove these barriers and inequalities in bereavement support services for those who live rurally and have experienced perinatal and infant loss. Results of this study indicate the need for further study and establishment of bereavement resources in rural outreach for perinatal and early childhood loss.

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