WLC32-6: A Cell Search Technique based on Known Postfix for OFDM Cellular Systems

ABSTRACT Bacterial cell morphogenesis requires coordination among multiple cellular systems, including the bacterial cytoskeleton and the cell wall. In the vibrioid bacterium Caulobacter crescentus, the intermediate filament-like protein crescentin forms a cell envelope-associated cytoskeletal structure that controls cell wall growth to generate cell curvature. We undertook a genetic screen to find other cellular components important for cell curvature. Here we report that deletion of a gene (wbqL) involved in the lipopolysaccharide (LPS) biosynthesis pathway abolishes cell curvature. Loss of WbqL function leads to the accumulation of an aberrant O-polysaccharide species and to the release of the S layer in the culture medium. Epistasis and microscopy experiments show that neither S-layer nor O-polysaccharide production is required for curved cell morphology per se but that production of the altered O-polysaccharide species abolishes cell curvature by apparently interfering with the ability of the crescentin structure to associate with the cell envelope. Our data suggest that perturbations in a cellular pathway that is itself fully dispensable for cell curvature can cause a disruption of cell morphogenesis, highlighting the delicate harmony among unrelated cellular systems. Using the wbqL mutant, we also show that the normal assembly and growth properties of the crescentin structure are independent of its association with the cell envelope. However, this envelope association is important for facilitating the local disruption of the stable crescentin structure at the division site during cytokinesis.

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A Multimedia and VoIP-Oriented Cell Search Technique for the IEEE 802.11 WLANS

Multimedia - A Multidisciplinary Approach to Complex Issues ◽

10.5772/36801 ◽

2012 ◽

Author(s):

Ahmed Riadh ◽

Mariam Fliss ◽

Sad Hanafi

Keyword(s):

Ieee 802.11 ◽

Search Technique ◽

Cell Search ◽

802.11 Wlans

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A self-exciting point process to study multi-cellular spatial signaling patterns

10.1101/2020.11.04.368001 ◽

2020 ◽

Author(s):

Archit Verma ◽

Siddhartha G. Jena ◽

Danielle R. Isakov ◽

Kazuhiro Aoki ◽

Jared E. Toettcher ◽

...

Keyword(s):

Point Process ◽

Point Processes ◽

Single Cells ◽

Cell Types ◽

Single Cell Protein ◽

Cellular Systems ◽

Cell Protein ◽

Drug Induced ◽

Spatiotemporal Model ◽

A Cell

Multi-cellular organisms rely on spatial signaling among cells to drive their organization, development, and response to stimuli. Several models have been proposed to capture the behavior of spatial signaling in multi-cellular systems, but existing approaches fail to capture both the autonomous behavior of single cells and the interactions of a cell with its neighbors simultaneously. We propose a spatiotemporal model of dynamic cell signaling based on Hawkes processes—self-exciting point processes—that model the signaling processes within a cell and spatial couplings between cells. With this cellular point process (CPP) model, we capture both the single-cell protein bursting rate and the magnitude and duration of signaling between cells relative to spatial locations. Furthermore, our model captures tissues composed of heterogeneous cell types with different bursting rates and signaling behaviors across multiple signaling proteins. We apply our model to epithelial cell systems that exhibit a range of autonomous and spatial signaling behaviors basally and under pharmacological exposure. Our model identifies known drug-induced signaling deficits, characterizes differences in signaling across a wound front, and generalizes to multi-channel observations.

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