Radioactive Counting Clocks

2006 ◽  
Author(s):  
Shankar Radhakrishnan ◽  
Amit Lal
Keyword(s):  
Radioactive Counting

Comments on “Optimization of the decision threshold for single radioactive counting”

2010 ◽  
Vol 98 (6) ◽  
Author(s):  
S. Sterlinski
Keyword(s):  
Decision Threshold ◽  
Radioactive Counting

AbstractIt is argued that in the recent papers by A. Vivier and J. Aupiais (Radiochim. Acta

Optimization of the decision threshold for single radioactive counting

2008 ◽  
Vol 96 (6) ◽  
Author(s):  
V. Vivier ◽  
Jean Aupiais
Keyword(s):  
Decision Threshold ◽  
Correct Data ◽  
Radioactive Counting

SummaryIn the above mentioned paper several misprints and errors in the formulae have been noticed. In particular, several equations were not properly writtten in terms of variables of integration. We now present the correct data.

scholarly journals Thromboembolic Surveillance Using 125 I Labelled Fibrinogen of 1000 Patients who Underwent Traumatologic and Orthopedic Surgery

1977 ◽  
Author(s):  
C. Marchai ◽  
C. Robert ◽  
M. Videgrain ◽  
L. Pourcelot
Keyword(s):  
Lumbar Spine ◽  
Orthopedic Surgery ◽  
Positive Test ◽  
Pulmonary Emboli ◽  
Subcutaneous Heparin ◽  
Preventive Medication ◽  
Traumatic Lesions ◽  
Fibrinogen Test ◽  
Radioactive Counting

From 1975 to 1977, 1006 tests using 125 I fibrinogen have been performed on orthopedic and traumatologic patients who were undergoing a thromboembolic treatment either by means of the association of dipyramidole and aspirin administered orally (24%) or by subcutaneous heparin (76%). The 125 I fibrinogen was injected preoperatively or immediately postoperatively. A daily radioactive counting was performed on the inferior members for approximately 6 to 8 days. 102 venous phlebography controls demonstrated an accuracy of 80% for the 125 I fibrinogen test. Of 1006 patients, 15.2% of the fibrinogen tests were positive, 59.7% of which were positive between the first and fifth postoperative day (p<0.02). The isotopic signs of venous thrombosis occurred in 21% of the hip surgery patients, 14.5% of the lumbar spine surgeries, 13% of the knee surgeries, and 11.5% of the patients who underwent surgery for other traumatic lesions. In these 1006 patients, 9 pulmonary emboli occurred of which 2 were fatal. The 125 I fibrinogen test can only be applied to evolutive thrombosis and does not permit one to differentiate between hematomas and thrombosis, nor to detect pelvic thrombosis. However, this test still remains a simple, faithful, and nontraumatic diagnostic tool in the early detection of thrombosis of the inferior members in patients undergoing traumatologic and orthopedic surgery. Moreover, the labelled fibrinogen test is useful in the determination of the efficacy of antithrombotic preventive medication. Our study has manifested the superiority of subcutaneous heparin (18% positive test) over the association of dipyramidole-aspirin (38.6% positive test) in the prevention of thromboembolic accidents in hip patients (p<0.001).

Cardiac function after embolization of coronaries with microspheres

1963 ◽  
Vol 204 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Hubert L. Stone ◽  
Vernon S. Bishop ◽  
Arthur C. Guyton
Keyword(s):  
Cardiac Output ◽  
Cardiac Function ◽  
Cardiac Failure ◽  
Functional Ability ◽  
Maximum Level ◽  
Left Ventricular ◽  
Work Output ◽  
Vicious Cycle ◽  
Radioactive Microspheres ◽  
Radioactive Counting

Radioactive microspheres were injected into the coronary systems of 11 dogs, and the quantity of microspheres entering and remaining in the coronary system was determined by radioactive counting techniques. After progressive injection of small quantities of microspheres over a period of 2–3 hr, leading finally to death by cardiac failure, the total volume of microspheres remaining in the coronary system averaged only 6.5 mm3. The pumping ability of the heart at different degrees of embolization was measured by determining successive cardiac function curves, both cardiac output curves and left ventricular minute work curves. In each experiment, both the maximum cardiac output and maximum minute work output decreased approximately proportionately after each individual injection of incremental quantities of microspheres, illustrating that the functional ability of the heart can be expressed very well by the maximum level of these function curves. In all experiments, the cardiac function curves began to deteriorate spontaneously after injection of a very critical quantity of microspheres, and a vicious cycle of deterioration occurred thereafter, resulting in rapid demise of the animal.

scholarly journals Platelet Prostaglandin Endoperoxides Formation in Hyperlipidemias

1977 ◽  
Author(s):  
R. Bizios ◽  
L.K. Wong ◽  
R. Vaillancourt ◽  
R.S. Lees ◽  
A.C. Carvalho
Keyword(s):  
Thromboxane A2 ◽  
Type Ii ◽  
Reaction Products ◽  
Ringer’S Solution ◽  
Type Iv ◽  
Tlc Plates ◽  
Platelet Release ◽  
Layer Chromatography ◽  
Radioactive Counting

To evaluate the role of prostaglandin endoperoxide formation in the mechanism(s) of platelet hypersensitivity in hyperlipoproteinemias, a study was undertaken in 8 type II patients, 3 type IV, and 8 normal volunteers. Platelet aggregation and release were studied in all subjects. Simultaneously, EDTA-platelets were washed by centrifugation and suspended in modified Ringer’s solution. One ml suspensions (0.8-1x106/μl) were added to 4.5μg of 14C-Arachidonic Acid (AA; sp. act. 50 mCi/mmol) and incubated for 30 sec and 5 min at 37°C. The methylated reaction products were separated by thin layer chromatography. AA, PGE2, PGF2α, and thromboxane B2 (PHD) (Upjohn) were used to identify and locate the respective bands. The products were analyzed by mass spectrometry. TLC-plates were both scanned and scraped for radioactive counting. The chromatograms displayed a pattern similar to that reported by Samuelsson et al. Compared with normal, hypersensitive platelets of type II patients generated 25% more thromboxane A2 (TXA2) after 30 sec incubation with AA, while at 5 min PHD was increased by 30% and TXA2 was still elevated by a factor of 2. The behavior of type IV platelets was similar to normal.Aspirin-treated platelets produced one product (HETE). Among the AA derivatives studied, only eluted TXA2 induced platelet release.Our data suggest that platelet hyperreactivity in type II patients may be mediated by the increased production and long survival of thromboxane A2.

scholarly journals A Cox model for radioactive counting measure: Inference on the intensity process

2010 ◽  
Vol 103 (2) ◽  
pp. 116-121 ◽  
Author(s):  
P.R. Bouzas ◽  
N. Ruiz-Fuentes ◽  
A. Matilla ◽  
A.M. Aguilera ◽  
M.J. Valderrama
Keyword(s):  
Cox Model ◽  
Counting Measure ◽  
Intensity Process ◽  
Radioactive Counting
Sign in / Sign up

Export Citation Format

Share Document