Low-latency VLSI architecture for neural cross-frequency coupling analysis

2017 ◽  
Author(s):  
Gerard O'Leary ◽  
Taufik A. Valiante ◽  
Roman Genov
Keyword(s):  
Vlsi Architecture ◽  
Low Latency ◽  
Coupling Analysis ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

scholarly journals Epileptogenic Zone Location of Temporal Lobe Epilepsy by Cross-Frequency Coupling Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Xiaotong Liu ◽  
Fang Han ◽  
Rui Fu ◽  
Qingyun Wang ◽  
Guoming Luan
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Single Channel ◽  
Brain Networks ◽  
Brain Regions ◽  
Functional Network ◽  
Epileptogenic Zone ◽  
Coupling Analysis ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

Epilepsy is a chronic brain disease with dysfunctional brain networks, and electroencephalography (EEG) is an important tool for epileptogenic zone (EZ) identification, with rich information about frequencies. Different frequency oscillations have different contributions to brain function, and cross-frequency coupling (CFC) has been found to exist within brain regions. Cross-channel and inter-channel analysis should be both focused because they help to analyze how epilepsy networks change and also localize the EZ. In this paper, we analyzed long-term stereo-electroencephalography (SEEG) data from 17 patients with temporal lobe epilepsy. Single-channel and cross-channel CFC features were combined to establish functional brain networks, and the network characteristics under different periods and the localization of EZ were analyzed. It was observed that theta–gamma phase amplitude coupling (PAC) within the electrodes in the seizure region increased during the ictal (p < 0.05). Theta–gamma and delta–gamma PAC of cross-channel were enhanced in the early and mid-late ictal, respectively. It was also found that there was a strong cross-frequency coupling state between channels of EZ in the functional network during the ictal, along with a more regular network than interictal. The accuracy rate of EZ localization was 82.4%. Overall, the combination of single-channel and multi-channel cross-band coupling analysis can help identify seizures and localize EZ for temporal lobe epilepsy. Rhythmic coupling reveals a relationship between the functional network and the seizure status of epilepsy.

scholarly journals Delta-mediated cross-frequency coupling organizes oscillatory activity across the rat cortico-basal ganglia network

2013 ◽  
Vol 7 ◽  
Author(s):  
Jon López-Azcárate ◽  
María Jesús Nicolás ◽  
Ivan Cordon ◽  
Manuel Alegre ◽  
Miguel Valencia ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Oscillatory Activity ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

scholarly journals Gamma Oscillations and Their Cross-frequency Coupling in the Primate Hippocampus during Sleep

SLEEP ◽  
2015 ◽  
Vol 38 (7) ◽  
pp. 1085-1091 ◽  
Author(s):  
Saori Takeuchi ◽  
Tatsuya Mima ◽  
Rie Murai ◽  
Hideki Shimazu ◽  
Yoshikazu Isomura ◽  
...  
Keyword(s):  
Gamma Oscillations ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

scholarly journals Working Memory and Cross-Frequency Coupling of Neuronal Oscillations

2021 ◽  
Vol 12 ◽  
Author(s):  
Mohammed Abubaker ◽  
Wiam Al Qasem ◽  
Eugen Kvašňák
Keyword(s):  
Working Memory ◽  
Cognitive Impairment ◽  
Brain Stimulation ◽  
Large Body ◽  
Cognitive Outcomes ◽  
Essential Component ◽  
Non Invasive ◽  
Transcranial Alternating Current Stimulation ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

Working memory (WM) is the active retention and processing of information over a few seconds and is considered an essential component of cognitive function. The reduced WM capacity is a common feature in many diseases, such as schizophrenia, attention deficit hyperactivity disorder (ADHD), mild cognitive impairment (MCI), and Alzheimer's disease (AD). The theta-gamma neural code is an essential component of memory representations in the multi-item WM. A large body of studies have examined the association between cross-frequency coupling (CFC) across the cerebral cortices and WM performance; electrophysiological data together with the behavioral results showed the associations between CFC and WM performance. The oscillatory entrainment (sensory, non-invasive electrical/magnetic, and invasive electrical) remains the key method to investigate the causal relationship between CFC and WM. The frequency-tuned non-invasive brain stimulation is a promising way to improve WM performance in healthy and non-healthy patients with cognitive impairment. The WM performance is sensitive to the phase and rhythm of externally applied stimulations. CFC-transcranial-alternating current stimulation (CFC-tACS) is a recent approach in neuroscience that could alter cognitive outcomes. The studies that investigated (1) the association between CFC and WM and (2) the brain stimulation protocols that enhanced WM through modulating CFC by the means of the non-invasive brain stimulation techniques have been included in this review. In principle, this review can guide the researchers to identify the most prominent form of CFC associated with WM processing (e.g., theta/gamma phase-amplitude coupling), and to define the previously published studies that manipulate endogenous CFC externally to improve WM. This in turn will pave the path for future studies aimed at investigating the CFC-tACS effect on WM. The CFC-tACS protocols need to be thoroughly studied before they can be considered as therapeutic tools in patients with WM deficits.

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