A 110-nW in-channel sigma-delta converter for large-scale neural recording implants

2016 ◽  
Author(s):  
M. Rezaei ◽  
E. Maghsoudloo ◽  
M. Sawan ◽  
B. Gosselin
Keyword(s):  
Large Scale ◽  
Neural Recording ◽  
Sigma Delta

Wireless Gigabit Data Telemetry for Large-Scale Neural Recording

2015 ◽  
pp. 1-1 ◽  
Author(s):  
Yen-Cheng Kuan ◽  
Yi-Kai Lo ◽  
Yanghyo Kim ◽  
Mau-Chung Frank Chang ◽  
Wentai Liu
Keyword(s):  
Large Scale ◽  
Neural Recording

scholarly journals A high-density carbon fiber neural recording array technology

2018 ◽  
Author(s):  
Travis L Massey ◽  
Samantha R Santacruz ◽  
Jason F Hou ◽  
Kristofer SJ Pister ◽  
Jose M Carmena ◽  
...  
Keyword(s):  
Carbon Fiber ◽  
Large Scale ◽  
Biological Response ◽  
Electrode Array ◽  
Neural Recording ◽  
Implanted Electrodes ◽  
Out Of Plane ◽  
Electrode Pitch ◽  
Isotropically Conductive Adhesive

Abstract.Objective: Microwire and Utah-style neural recording arrays are the predominant devices used for cortical neural recording, but the implanted electrodes cause a significant adverse biological response and suffer from well-studied performance degradation. Recent work has demonstrated that carbon fiber electrodes do not elicit this same adverse response, but these existing designs are not practically scalable to hundreds or thousands of recording sites. We present technology that overcomes these issues while additionally providing fine electrode pitch for spatial oversampling.Approach: We present a 32-channel carbon fiber monofilament-based intracortical neural recording array fabricated through a combination of bulk silicon microfabrication processing and microassembly. This device represents the first truly two-dimensional carbon fiber neural recording array. The density, channel count, and size scale of this array are enabled by an out-of-plane microassembly technique in which individual fibers are inserted through metallized and isotropically conductive adhesive-filled holes in an oxide-passivated microfabricated silicon substrate.Main results: Five-micron diameter fibers are spaced at a pitch of 38 microns, four times denser than state of the art one-dimensional arrays. The fine diameter of the carbon fibers affords both minimal cross-section and nearly three orders of magnitude greater lateral compliance than standard tungsten microwires. Typical 1 kHz impedances are on the order of hundreds of kiloohms, and successful in vivo recording is demonstrated in the motor cortex of a rat. 22 total units are recorded on 20 channels, with unit SNR ranging from 0.85 to 4.2.Significance: This is the highest density microwire-style electrode array to date, and this fabrication technique is scalable to a larger number of electrodes and allows for the potential future integration of microelectronics. Large-scale carbon fiber neural recording arrays are a promising technology for reducing the inflammatory response and increasing the information density, particularly in neural recording applications where microwire arrays are already used.

scholarly journals Scalable, Modular Three-Dimensional Silicon Microelectrode Assembly via Electroless Plating

Micromachines ◽  
2018 ◽  
Vol 9 (9) ◽  
pp. 436 ◽  
Author(s):  
Jörg Scholvin ◽  
Anthony Zorzos ◽  
Justin Kinney ◽  
Jacob Bernstein ◽  
Caroline Moore-Kochlacs ◽  
...  
Keyword(s):  
Large Scale ◽  
Electrical Contact ◽  
Three Dimensional ◽  
Electroless Nickel ◽  
Neural Recording ◽  
Mammalian Brain ◽  
Electroless Nickel Plating ◽  
Nickel Plating ◽  
The Individual ◽  
Electrical Connections

We devised a scalable, modular strategy for microfabricated 3-D neural probe synthesis. We constructed a 3-D probe out of individual 2-D components (arrays of shanks bearing close-packed electrodes) using mechanical self-locking and self-aligning techniques, followed by electroless nickel plating to establish electrical contact between the individual parts. We detail the fabrication and assembly process and demonstrate different 3-D probe designs bearing thousands of electrode sites. We find typical self-alignment accuracy between shanks of <0.2° and demonstrate orthogonal electrical connections of 40 µm pitch, with thousands of connections formed electrochemically in parallel. The fabrication methods introduced allow the design of scalable, modular electrodes for high-density 3-D neural recording. The combination of scalable 3-D design and close-packed recording sites may support a variety of large-scale neural recording strategies for the mammalian brain.

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