Analysis of locality-sensitive hashing for fast critical event prediction on physiological time series

2016 ◽  
Author(s):  
Yongwook Bryce Kim ◽  
Una-May O'Reilly
Keyword(s):  
Time Series ◽  
Locality Sensitive Hashing ◽  
Critical Event ◽  
Event Prediction ◽  
Physiological Time

scholarly journals Understanding vasopressor intervention and weaning: risk prediction in a public heterogeneous clinical time series database

2016 ◽  
Vol 24 (3) ◽  
pp. 488-495 ◽  
Author(s):  
Mike Wu ◽  
Marzyeh Ghassemi ◽  
Mengling Feng ◽  
Leo A Celi ◽  
Peter Szolovits ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Time Series ◽  
Intensive Care ◽  
Receiver Operating Curve ◽  
Post Discharge ◽  
Control Hypotension ◽  
Health Records ◽  
Physiological Time ◽  
Large Populations ◽  
Switching State

Background: The widespread adoption of electronic health records allows us to ask evidence-based questions about the need for and benefits of specific clinical interventions in critical-care settings across large populations. Objective: We investigated the prediction of vasopressor administration and weaning in the intensive care unit. Vasopressors are commonly used to control hypotension, and changes in timing and dosage can have a large impact on patient outcomes. Materials and Methods: We considered a cohort of 15 695 intensive care unit patients without orders for reduced care who were alive 30 days post-discharge. A switching-state autoregressive model (SSAM) was trained to predict the multidimensional physiological time series of patients before, during, and after vasopressor administration. The latent states from the SSAM were used as predictors of vasopressor administration and weaning. Results: The unsupervised SSAM features were able to predict patient vasopressor administration and successful patient weaning. Features derived from the SSAM achieved areas under the receiver operating curve of 0.92, 0.88, and 0.71 for predicting ungapped vasopressor administration, gapped vasopressor administration, and vasopressor weaning, respectively. We also demonstrated many cases where our model predicted weaning well in advance of a successful wean. Conclusion: Models that used SSAM features increased performance on both predictive tasks. These improvements may reflect an underlying, and ultimately predictive, latent state detectable from the physiological time series.

scholarly journals Quantifying Memory in Complex Physiological Time-Series

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e72854 ◽  
Author(s):  
Amir H. Shirazi ◽  
Mohammad R. Raoufy ◽  
Haleh Ebadi ◽  
Michele De Rui ◽  
Sami Schiff ◽  
...  
Keyword(s):  
Time Series ◽  
Physiological Time

Nonlinear Analysis of Physiological Time Series

2009 ◽  
pp. 307-333 ◽  
Author(s):  
Anisoara Paraschiv-Ionescu ◽  
Kamiar Aminian
Keyword(s):  
Time Series ◽  
Nonlinear Analysis ◽  
Physiological Time
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