Sheathless and high throughput sorting of paramagnetic microparticles in a magneto-hydrodynamic microfluidic device

2016 ◽  
Author(s):  
Vikash Kumar ◽  
Pouya Rezai
Keyword(s):  
Microfluidic Device ◽  
High Throughput ◽  
Paramagnetic Microparticles

scholarly journals Generation of Gradients on a Microfluidic Device: Toward a High-Throughput Investigation of Spermatozoa Chemotaxis

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0142555 ◽  
Author(s):  
Yi Zhang ◽  
Rong-Rong Xiao ◽  
Tailang Yin ◽  
Wei Zou ◽  
Yun Tang ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
High Throughput

Abstract 444: Continuous, high throughput microfluidic device to monitor circulating tumor cells in cancer patients

2019 ◽  
Author(s):  
Kaylee Smith ◽  
Tae Hyun Kim ◽  
Costanza Paoletti ◽  
Douglas H. Thamm ◽  
Daniel F. Hayes ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Microfluidic Device ◽  
High Throughput

A Multilayer Polymer-Film Inertial Microfluidic Device for High-Throughput Cell Concentration

2019 ◽  
Vol 91 (8) ◽  
pp. 5461-5468 ◽  
Author(s):  
Nan Xiang ◽  
Rui Zhang ◽  
Yu Han ◽  
Zhonghua Ni
Keyword(s):  
Polymer Film ◽  
Microfluidic Device ◽  
High Throughput ◽  
Cell Concentration

scholarly journals High-Throughput Mechanotransduction in Drosophila Embryos with a Microfluidic Device

2018 ◽  
Vol 114 (3) ◽  
pp. 325a
Author(s):  
Ardon Z. Shorr ◽  
Utku Sönmez ◽  
Jonathan S. Minden ◽  
Philip R. LeDuc
Keyword(s):  
Microfluidic Device ◽  
High Throughput ◽  
Drosophila Embryos

High-throughput deterministic single-cell encapsulation and droplet pairing, fusion, and shrinkage in a single microfluidic device

2013 ◽  
Vol 35 (2-3) ◽  
pp. 385-392 ◽  
Author(s):  
Rogier M. Schoeman ◽  
Evelien W.M. Kemna ◽  
Floor Wolbers ◽  
Albert van den Berg
Keyword(s):  
Single Cell ◽  
Microfluidic Device ◽  
High Throughput ◽  
Cell Encapsulation ◽  
Single Cell Encapsulation

scholarly journals High-throughput separation in a microfluidic device with multiple contacting regions

2009 ◽  
Vol 25 ◽  
pp. S164
Author(s):  
R.C. Kolfschoten ◽  
A.E.M. Janssen ◽  
R.M. Boom
Keyword(s):  
Microfluidic Device ◽  
High Throughput

scholarly journals A microfluidic device and computational platform for high-throughput live imaging of gene expression

2012 ◽  
Vol 9 (11) ◽  
pp. 1101-1106 ◽  
Author(s):  
Wolfgang Busch ◽  
Brad T Moore ◽  
Bradley Martsberger ◽  
Daniel L Mace ◽  
Richard W Twigg ◽  
...  
Keyword(s):  
Gene Expression ◽  
Microfluidic Device ◽  
High Throughput ◽  
Live Imaging ◽  
Computational Platform

scholarly journals Aspiration-mediated hydrogel micropatterning using rail-based open microfluidic devices for high-throughput 3D cell culture

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dohyun Park ◽  
Jungseub Lee ◽  
Younggyun Lee ◽  
Kyungmin Son ◽  
Jin Woo Choi ◽  
...  
Keyword(s):  
Cell Culture ◽  
Capillary Pressure ◽  
Microfluidic Device ◽  
High Throughput ◽  
3D Cell Culture ◽  
Microfluidic Devices ◽  
Cell Types ◽  
Human Organ ◽  
Patterning Technique ◽  
Experimental Yield

AbstractMicrofluidics offers promising methods for aligning cells in physiologically relevant configurations to recapitulate human organ functionality. Specifically, microstructures within microfluidic devices facilitate 3D cell culture by guiding hydrogel precursors containing cells. Conventional approaches utilize capillary forces of hydrogel precursors to guide fluid flow into desired areas of high wettability. These methods, however, require complicated fabrication processes and subtle loading protocols, thus limiting device throughput and experimental yield. Here, we present a swift and robust hydrogel patterning technique for 3D cell culture, where preloaded hydrogel solution in a microfluidic device is aspirated while only leaving a portion of the solution in desired channels. The device is designed such that differing critical capillary pressure conditions are established over the interfaces of the loaded hydrogel solution, which leads to controlled removal of the solution during aspiration. A proposed theoretical model of capillary pressure conditions provides physical insights to inform generalized design rules for device structures. We demonstrate formation of multiple, discontinuous hollow channels with a single aspiration. Then we test vasculogenic capacity of various cell types using a microfluidic device obtained by our technique to illustrate its capabilities as a viable micro-manufacturing scheme for high-throughput cellular co-culture.

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