Novel protein weight matrix generated from amino acid indices

2015 ◽  
Author(s):  
Charalambos Chrysostomou ◽  
Huseyin Seker
Keyword(s):  
Amino Acid ◽  
Weight Matrix ◽  
Amino Acid Indices ◽  
Novel Protein

scholarly journals Predicting disordered regions in proteins using the profiles of amino acid indices

2009 ◽  
Vol 10 (Suppl 1) ◽  
pp. S42 ◽  
Author(s):  
Pengfei Han ◽  
Xiuzhen Zhang ◽  
Zhi-Ping Feng
Keyword(s):  
Amino Acid ◽  
Amino Acid Indices ◽  
Disordered Regions

A novel protein distance matrix based on the minimum arc-length between two amino-acid residues on the surface of a globular protein

2014 ◽  
Vol 190-191 ◽  
pp. 50-55 ◽  
Author(s):  
Damien Hall ◽  
Songling Li ◽  
Kazuo Yamashita ◽  
Ryuzo Azuma ◽  
John A. Carver ◽  
...  
Keyword(s):  
Amino Acid ◽  
Distance Matrix ◽  
Globular Protein ◽  
Amino Acid Residues ◽  
Arc Length ◽  
Protein Distance ◽  
Novel Protein

scholarly journals Identification of cut8+ and cek1+, a novel protein kinase gene, which complement a fission yeast mutation that blocks anaphase.

1994 ◽  
Vol 14 (9) ◽  
pp. 6361-6371 ◽  
Author(s):  
I Samejima ◽  
M Yanagida
Keyword(s):  
Amino Acid ◽  
Protein Kinase ◽  
Fission Yeast ◽  
Gene Product ◽  
Budding Yeast ◽  
Essential Gene ◽  
Restrictive Temperature ◽  
Kinase Gene ◽  
Yeast Saccharomyces Cerevisiae ◽  
Novel Protein

The fission yeast Schizosaccharomyces pombe [corrected] temperature sensitivity cut8-563 mutation causes chromosome overcondensation and short spindle formation in the absence of sister chromatid separation. The cut8-563 mutation allows cytokinesis before the completion of anaphase, thus producing cells with a cut phenotype. The cut8+ gene product may be required for normal progression of anaphase. Diploidization occurs at the restrictive temperature, and 60 to 70% of the cells surviving after two generations are diploid. These phenotypes are reminiscent of those of budding yeast (Saccharomyces cerevisiae) ctf13 and ctf14 (ndc10) mutations. The cut8+ gene, isolated by complementation of the mutant, predicts a 262-amino-acid protein; the amino and carboxy domains are hydrophilic, while the central domain contains several hydrophobic stretches. It has a weak overall similarity to the budding yeast DBF8 gene product. DBF8 is an essential gene whose mutations result in delay in mitotic progression and chromosome instability. Anti-cut8 antibodies detect a 33-kDa polypeptide. Two multicopy suppressor genes for cut8-563 are identified. They are the cut1+ gene essential for nuclear division, and a new gene (designated cek1+) which encodes a novel protein kinase. The cek1+ gene product is unusually large (1,309 amino acids) and has a 112-amino-acid additional sequence in the kinase domain. The cek1+ gene is not an essential gene. Protein phosphorylation by cek1 may facilitate the progression of anaphase through direct or indirect interaction with the cut8 protein.

Computational characterization of parallel dimeric and trimeric coiled-coils using effective amino acid indices

2015 ◽  
Vol 11 (2) ◽  
pp. 354-360 ◽  
Author(s):  
Chen Li ◽  
Xiao-Feng Wang ◽  
Zhen Chen ◽  
Ziding Zhang ◽  
Jiangning Song
Keyword(s):  
Amino Acid ◽  
Coiled Coil ◽  
Coiled Coils ◽  
Amino Acid Indices

RFCoil is a novel predictor for parallel coiled-coil dimer and trimer.

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