Cortical bone quality assessment using quantitative ultrasound on long bones

2012 ◽  
Author(s):  
Josquin Foiret ◽  
J. Minonzio ◽  
M. Talmant ◽  
P. Laugier
Keyword(s):  
Quality Assessment ◽  
Cortical Bone ◽  
Bone Quality ◽  
Quantitative Ultrasound ◽  
Long Bones

scholarly journals Bone Quality Assessment by Quantitative Ultrasound of Proximal Phalanxes of the Hand in Healthy Subjects Aged 3–21 Years

2001 ◽  
Vol 49 (5) ◽  
pp. 713-718 ◽  
Author(s):  
Giampiero I Baroncelli ◽  
Giovanni Federico ◽  
Silvano Bertelloni ◽  
Francesca De Terlizzi ◽  
Ruggero Cadossi ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Bone Quality ◽  
Quantitative Ultrasound ◽  
Healthy Subjects

Bone quality assessment at multiple skeletal sites using quantitative ultrasound imaging.

2010 ◽  
Vol 127 (3) ◽  
pp. 2034-2034
Author(s):  
Frederick Serra‐Hsu ◽  
Jiqi Cheng ◽  
Wei Lin ◽  
Yi‐Xian Qin
Keyword(s):  
Quality Assessment ◽  
Ultrasound Imaging ◽  
Bone Quality ◽  
Quantitative Ultrasound

scholarly journals Effect of Age on Bone Structure Parameters in Laying Hens

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 570
Author(s):  
Masayoshi Yamada ◽  
Chongxiao Chen ◽  
Toshie Sugiyama ◽  
Woo Kyun Kim
Keyword(s):  
Cortical Bone ◽  
Bone Quality ◽  
Bone Mineral ◽  
Volume Fraction ◽  
Bone Structure ◽  
Bone Volume ◽  
Egg Laying ◽  
Medullary Bone ◽  
Mineral Density ◽  
Tibial Diaphysis

Changes in medullary and cortical bone structure with age remain unclear. Twenty Hy-Line W36 hens, 25 or 52 weeks of age, were euthanized, and both tibiae were collected when an egg was present in the magnum. Serial cross sections of the tibiae were stained with Alcian blue. The bones were scanned using micro-computed tomography. Trabecular width (Tb.Wi) was significantly higher (p < 0.05) in 25-week-old hens, whereas medullary bone tissue volume (TV) was significantly higher (p < 0.01) in 52-week-old hens. 25-week-old hens had significantly higher (p < 0.01) bone volume fraction (BVF = calcified tissue / TV). Moreover, the cortical bone parameters were significantly higher (TV and bone mineral content (BMC) at p < 0.05, and bone volume (BV) and BVF at p < 0.01) in younger hens. Open porosity and total porosity, which indicate less density, were significantly higher (p < 0.01) in older hens. Older hens showed significantly higher (p < 0.01) tibial diaphysis TV than younger hens. Younger hens had significantly higher (p < 0.01) BV, BVF and bone mineral density (BMD) of the tibial diaphysis. These findings reveal that reductions in medullary bone quality might be associated with age-related low estrogen levels and stimulation of osteoclastic bone resorption by parathyroid hormone. Cortical bone quality decreased with enlargement of the Haversian canals and loss of volume, with a longer egg-laying period leading to osteoporosis.

Test Methods for Accurate and Robust Material Property Measurements of Rodent Cortical Bone

2008 ◽  
Author(s):  
Douglas J. Adams ◽  
Svetlana Lublinsky ◽  
Mauricio Barrero
Keyword(s):  
Cortical Bone ◽  
Material Property ◽  
Statistical Power ◽  
Test Methods ◽  
Standard Test ◽  
Long Bone ◽  
Long Bones ◽  
Tissue Properties ◽  
Serial Test ◽  
Direct Measurements

Direct measurements of cortical bone material properties are difficult to achieve in rodent long bones due to the inherently small dimensions and difficulties in machining standard test specimen geometries [1]. Bone tissue properties in nearly all rodent studies are thus limited to estimates from flexural tests of long bone diaphyses. In addition to the inaccuracies imposed by the bending stress state itself, these material property estimates are further confounded by the non-uniform geometry of long bones along the diaphyseal length. The goal of this work was to develop a series of techniques to improve the accuracy and precision of material property measurements in rodent long bones, with explicit mathematical correction for geometrical complexity and multiple measurements from individual bones. In combination, these techniques provide a pragmatic serial test routine for collecting multiple direct measurements of cortical tissue elastic modulus and strength, with a potential for improving sensitivity and statistical power in skeletal studies using rodents.

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