Development of a model predictive controller for an artificial pancreas

Author(s):  
M. El Hachimi ◽  
A. Ballouk ◽  
I. Khelafa ◽  
A. Baghdad
2020 ◽  
Vol 143 (2) ◽  
Author(s):  
Akshaya Kumar Patra ◽  
Anuja Nanda

Abstract During the past few decades, optimal control of blood glucose (BG) concentration with adequate feedback loop has been of ample importance for Type-I diabetes mellitus (TIDM) patients as far as an artificial pancreas realization is concerned. Now-a-days, in addition to the BG control, the design of the micro-insulin dispenser (MID) with a robust control algorithm to regulate the other chronic clinical disorders based on prolonged medications is also quite indispensable. A novel Kalman filtering model predictive controller (KFMPC) has been proposed in this work to solve the aforementioned problem. For designing of the KFMPC, a ninth-order state-space model of the TIDM patient with MID is considered. In this control strategy, the conventional model predictive controller is re-formulated with a state estimator based on the Kalman filtering methodology to improve the control execution. The justification of enhanced control performance of KFMPC is demonstrated by comparative result analysis with other published control techniques. The simulations are carried out through matlab/simulink environment, and the results indicate comparatively better control ability of the suggested algorithm to control the BG level within the normoglycemic range (70–120 mg/dl) as far as accuracy, stability, quick damping, and robustness.


Author(s):  
Abdennaceur Baghdad ◽  
Mohamed El Hachimi ◽  
Abdelhakim Ballouk ◽  
Ilyass Khelafa

2014 ◽  
Vol 47 (3) ◽  
pp. 10144-10149 ◽  
Author(s):  
Mirko Messori ◽  
Enrico Fornasiero ◽  
Chiara Toffanin ◽  
Claudio Cobelli ◽  
Lalo Magni

Author(s):  
Waleed Khalid Al-Azzawi

Diabetes is known as the major cause of death in the world leading to kidney, retinopathy and cardiovascular diseases as well. In this paper, a Robust Model Predictive Controller (RMPC) is introduced to design artificial pancreas that solved the model uncertainty and keep the blood glucose level in the normal range by regulating the size of insulin infusion from pump based on RMPC. The simulation results will present a good performance of the proposed controller to avoid disturbance and robustness against uncertainties.


Author(s):  
Mohamed El Hachimi ◽  
Abdelhakim Ballouk ◽  
Ilyass Khelafa ◽  
Abdennaceur Baghdad

Author(s):  
Mohamed El Hachimi ◽  
Abdelhakim Ballouk ◽  
AbdNaceur Baghdad

This work consists on new tuning of Model Predictive Controllers using Fuzzy Logic method. Tree relevant parameters are automatically adjusted the prediction horizon Np, the input weight R and the output weight Q. The proposed controller is implemented in an Artificial Pancreas and tested under realistic conditions in a commercial platform of simulation. The result of the simulations revealed the success of such a method to improve the controller’s performances compared to the previous ones.


Author(s):  
Fatemeh Khani ◽  
Mohammad Haeri

Industrial processes are inherently nonlinear with input, state, and output constraints. A proper control system should handle these challenging control problems over a large operating region. The robust model predictive controller (RMPC) could be an linear matrix inequality (LMI)-based method that estimates stability region of the closed-loop system as an ellipsoid. This presentation, however, restricts confident application of the controller on systems with large operating regions. In this paper, a dual-mode control strategy is employed to enlarge the stability region in first place and then, trajectory reversing method (TRM) is employed to approximate the stability region more accurately. Finally, the effectiveness of the proposed scheme is illustrated on a continuous stirred tank reactor (CSTR) process.


Sign in / Sign up

Export Citation Format

Share Document