The device for generating cold plasma in an electrically conductive solution, with the aim of tissue spare

Author(s):  
Nabat A. Zhumantaeva ◽  
Lilia I. Lisitsyna ◽  
Alexander N. Aleinik ◽  
Valery V. Pedder
Author(s):  
K. A. Fisher ◽  
M. G. L. Gustafsson ◽  
M. B. Shattuck ◽  
J. Clarke

The atomic force microscope (AFM) is capable of imaging electrically conductive and non-conductive surfaces at atomic resolution. When used to image biological samples, however, lateral resolution is often limited to nanometer levels, due primarily to AFM tip/sample interactions. Several approaches to immobilize and stabilize soft or flexible molecules for AFM have been examined, notably, tethering coating, and freezing. Although each approach has its advantages and disadvantages, rapid freezing techniques have the special advantage of avoiding chemical perturbation, and minimizing physical disruption of the sample. Scanning with an AFM at cryogenic temperatures has the potential to image frozen biomolecules at high resolution. We have constructed a force microscope capable of operating immersed in liquid n-pentane and have tested its performance at room temperature with carbon and metal-coated samples, and at 143° K with uncoated ferritin and purple membrane (PM).


2010 ◽  
Vol 31 (3) ◽  
pp. 353-359
Author(s):  
Xiaoyan CHAI ◽  
Shuyong SHANG ◽  
Gaihuan LIU ◽  
Xumei TAO ◽  
Xiang LI ◽  
...  

2013 ◽  
Vol 17 (9) ◽  
pp. 892-899 ◽  
Author(s):  
Ana Paula Costa ◽  
Mohamed Naceur Belgacem ◽  
Manuel Santos Silva ◽  
Wim Thielemans ◽  
Carla Gaiolas
Keyword(s):  

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