Electrochemical Biosensors and Microfluidics in Organic System-on-Package Technology

2007 ◽  
Author(s):  
Janagama D. Goud ◽  
P. Markondeya Raj ◽  
Jin Liu ◽  
Roger Narayan ◽  
Mahadevan Iyer ◽  
...  
Keyword(s):  
Electrochemical Biosensors ◽  
Organic System

Sequestration of carbon oxide in different fertilization systems in agrocenoses

2018 ◽  
Vol 5 (2) ◽  
pp. 37-51 ◽  
Author(s):  
O. Demydenko ◽  
Yu. Zapasna ◽  
V. Velychko
Keyword(s):  
Crop Rotation ◽  
Carbon Oxide ◽  
Organic Fertilizers ◽  
Forest Steppe ◽  
Organic Fertilization ◽  
Organic System ◽  
Capacity Level ◽  
Medium Level ◽  
Fertilization System ◽  
By Products

Aim. To substantiate the agroecological estimation of the performance of a short crop rotation in conditions of intense and organic system of fertilization on the basis of restoring normative parameters of emission and se- questration of С-СО 2 circulation while using by-products as organic fertilizers in conditions of modern climatic system of the Forest-Steppe of Ukraine. Methods. Field, statistical, laboratory. Results of Investigations. The performance of short crop rotations is determined by the capacity of С-СО 2 balance. Strong inverse correla- tion was found between the capacity of N and the ratio between C and N in the agrocenosis, which demon- strated that enhancing the humifi cation processes (ratio constriction) led to the increase in the capacity of С org balance and the decrease in the capacity level of С-СО 2 balance (enhancing mineralization), related to the reduction in the performance of crops in the agrocenosis of a crop rotation compared to the organic system of fertilization. The capacity of С-СО 2 and С org balance correlates at the medium level of inverse direction, and the yield of the main products, feed units and digestible protein correlates at the level of strong direct correlation. Conclusions. General mineralization of by-products and humus in the agrocenosis and humifi cation processes are antagonists, so extending the ratio between С and N at the intense fertilization system stimulates the in- crease in performance and reducing С to N similar to the organic fertilization system enhances the humifi cation process due to binding of С org into humus and limits mineralization which leads to the reduction in agrocenosis performance at the organic fertilization system.

Compiler-Aided Run-Time Performance Speed-Up in Super-Scalar Processor

10.28945/3391 ◽  
2009 ◽  
Author(s):  
Moshe Pelleh
Keyword(s):  
Embedded Systems ◽  
Embedded System ◽  
General Purpose ◽  
Experimental Results ◽  
Medium Size ◽  
Organic System ◽  
Software Application ◽  
Organic Systems ◽  
Special Cases ◽  
Run Time

In our world, where most systems become embedded systems, the approach of designing embedded systems is still frequently similar to the approach of designing organic systems (or not embedded systems). An organic system, like a personal computer or a work station, must be able to run any task submitted to it at any time (with certain constrains depending on the machine). Consequently, it must have a sophisticated general purpose Operating System (OS) to schedule, dispatch, maintain and monitor the tasks and assist them in special cases (particularly communication and synchronization between them and with external devices). These OSs require an overhead on the memory, on the cache and on the run time. Moreover, generally they are task oriented rather than machine oriented; therefore the processor's throughput is penalized. On the other hand, an embedded system, like an Anti-lock Braking System (ABS), executes always the same software application. Frequently it is a small or medium size system, or made up of several such systems. Many small or medium size embedded systems, with limited number of tasks, can be scheduled by our proposed hardware architecture, based on the Motorola 500MHz MPC7410 processor, enhancing its throughput and avoiding the software OS overhead, complexity, maintenance and price. Encouraged by our experimental results, we shall develop a compiler to assist our method. In the meantime we will present here our proposal and the experimental results.

Electrochemical Biosensors as a Screening Tool of In Vitro DNA-Drug Interaction

2005 ◽  
Vol 1 (3) ◽  
pp. 217-224 ◽  
Author(s):  
Graziana Bagni ◽  
Mauro Ravera ◽  
Domenico Osella ◽  
Marco Mascini
Keyword(s):  
Drug Interaction ◽  
Screening Tool ◽  
Electrochemical Biosensors

scholarly journals The Role of Peptides in the Design of Electrochemical Biosensors for Clinical Diagnostics

Biosensors ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 246
Author(s):  
Patrick Severin Sfragano ◽  
Giulia Moro ◽  
Federico Polo ◽  
Ilaria Palchetti
Keyword(s):  
Functional Groups ◽  
Synthetic Peptides ◽  
Clinical Diagnostics ◽  
Electrochemical Biosensors ◽  
Practical Application ◽  
Design And Development ◽  
Electrode Surfaces ◽  
Electrochemical Transducers ◽  
Target Analyte

Peptides represent a promising class of biorecognition elements that can be coupled to electrochemical transducers. The benefits lie mainly in their stability and selectivity toward a target analyte. Furthermore, they can be synthesized rather easily and modified with specific functional groups, thus making them suitable for the development of novel architectures for biosensing platforms, as well as alternative labelling tools. Peptides have also been proposed as antibiofouling agents. Indeed, biofouling caused by the accumulation of biomolecules on electrode surfaces is one of the major issues and challenges to be addressed in the practical application of electrochemical biosensors. In this review, we summarise trends from the last three years in the design and development of electrochemical biosensors using synthetic peptides. The different roles of peptides in the design of electrochemical biosensors are described. The main procedures of selection and synthesis are discussed. Selected applications in clinical diagnostics are also described.

scholarly journals The Role of Selected Ecosystem Services in Different Farming Systems in Poland Regarding the Differentiation of Agricultural Land Structure

2021 ◽  
Vol 13 (12) ◽  
pp. 6673
Author(s):  
Lidia Luty ◽  
Kamila Musiał ◽  
Monika Zioło
Keyword(s):  
Ecosystem Services ◽  
Agricultural Land ◽  
Soil Formation ◽  
Farming Systems ◽  
Agricultural System ◽  
Organic System ◽  
Supporting Soil ◽  
Management Method ◽  
The Impact

The functioning of various agroecosystems is nowadays shaped by different farming systems, which may impair their functions, as well as being beneficial to them. The benefits include ecosystem services, defined as economic and noneconomic values gained by humans from ecosystems, through supporting soil formation and nutrient circulation, and the impact of agriculture on climate and biodiversity. Their mutual flow and various disturbances depend on the agroecosystem’s management method, which is associated with the type of management of agricultural land (AL) in individual farms. This paper raises a problem of transformation in the structure of three main farming systems in Poland, in 2004–2018, in relation to the implementation of 16 selected ecosystem services and their scale. Special attention was given to organic farming, as the most environmentally friendly and sustainable. The analysis demonstrates the increase in ALs in that type of production during the analyzed period of time. Disparities of transformation associated with the type of agricultural system were noticeable at the regional level, which were presented in 16 Polish voivodeships. The results of the analysis confirm that the organic system, which is an important carrier of various ecosystem services, gained a stable position. Moreover, areas with integrated farming still do not exceed 0.5% of total agricultural lands in such voivodeships. The analysis of factors influencing the deterioration or disappearance of selected environmental services characterizing agricultural systems indicates the need to depart from an intensive conventional management system.

scholarly journals Nutritional Value of Jerusalem Artichoke Tubers (Helianthus tuberosus L.) Grown in Organic System under Lithuanian and Polish Conditions

Agriculture ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 440
Author(s):  
Barbara Sawicka ◽  
Honorata Danilčenko ◽  
Elvyra Jariene ◽  
Dominika Skiba ◽  
Leszek Rachoń ◽  
...  
Keyword(s):  
Nutritional Value ◽  
Field Experiments ◽  
Geographic Location ◽  
Jerusalem Artichoke ◽  
Farming System ◽  
Biologically Active ◽  
Block Method ◽  
Organic System ◽  
Organic Farming System ◽  
True Protein

The aim of the study was to assess the nutritional value of H. tuberosus tubers grown in the organic farming system in Poland and Lithuania. The work was based on field experiments carried out in 2015–2017 in Parczew (Poland) and Akademija (Lithuania). The experiments were carried out using the randomized block method in four replications. Two cultivars of Jerusalem artichoke (JA) ‘Albik’ and ‘Rubik’ were tested. After the harvest of tubers, an assessment of their quality was carried out by standard methods. Due to the relocation of JA cultivation from Central and Eastern Europe to Northeast Europe, there were changes in the chemical composition of H. tuberosus tubers. The tubers from crops in Lithuania were characterized by a lower content of inulin, crude fiber and protein, ascorbic acid, total and endogenous amino acids than in Poland, but a higher content of true protein and macroelements. Edaphic factors determined, to a greater extent than genetic factors, the nutritional value of tubers. Assessment of the influence of varietal characteristics, meteorological conditions, and geographic location on the amount of biologically active compounds in JA will allow growers and consumers to choose the most suitable cultivars.

scholarly journals Electrochemical Biosensors for Cytokine Profiling: Recent Advancements and Possibilities in the Near Future

Biosensors ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 94
Author(s):  
Nirmita Dutta ◽  
Peter B. Lillehoj ◽  
Pedro Estrela ◽  
Gorachand Dutta
Keyword(s):  
Immune System ◽  
Cost Effective ◽  
Anomalous Behavior ◽  
Quantitative Detection ◽  
Electrochemical Biosensors ◽  
Aberrant Expression ◽  
Detection Techniques ◽  
Short Period ◽  
User Friendly ◽  
Cytokine Profiling

Cytokines are soluble proteins secreted by immune cells that act as molecular messengers relaying instructions and mediating various functions performed by the cellular counterparts of the immune system, by means of a synchronized cascade of signaling pathways. Aberrant expression of cytokines can be indicative of anomalous behavior of the immunoregulatory system, as seen in various illnesses and conditions, such as cancer, autoimmunity, neurodegeneration and other physiological disorders. Cancer and autoimmune diseases are particularly adept at developing mechanisms to escape and modulate the immune system checkpoints, reflected by an altered cytokine profile. Cytokine profiling can provide valuable information for diagnosing such diseases and monitoring their progression, as well as assessing the efficacy of immunotherapeutic regiments. Toward this goal, there has been immense interest in the development of ultrasensitive quantitative detection techniques for cytokines, which involves technologies from various scientific disciplines, such as immunology, electrochemistry, photometry, nanotechnology and electronics. This review focusses on one aspect of this collective effort: electrochemical biosensors. Among the various types of biosensors available, electrochemical biosensors are one of the most reliable, user-friendly, easy to manufacture, cost-effective and versatile technologies that can yield results within a short period of time, making it extremely promising for routine clinical testing.

scholarly journals Label-Free Electrochemical Test of Protease Interaction with a Peptide Substrate Modified Gold Electrode

Chemosensors ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 199
Author(s):  
Anna Wcisło ◽  
Izabela Małuch ◽  
Paweł Niedziałkowski ◽  
Tadeusz Ossowski ◽  
Adam Prahl
Keyword(s):  
Gold Electrode ◽  
High Selectivity ◽  
Electrode Materials ◽  
Electrochemical Biosensors ◽  
Electrochemical Characteristics ◽  
Label Free ◽  
Peptide Substrate ◽  
Electrochemical Test ◽  
Experimental Conditions ◽  
Spectrofluorimetric Method

Efficient deposition of biomolecules on the surface, maintaining their full activity and stability, is a most significant factor in biosensor construction. For this reason, more and more research is focused on the development of electrochemical biosensors that have the ability to electrically detect adsorbed molecules on electrode surface with high selectivity and sensitivity. The presented research aims to develop an efficient methodology that allows quantification of processes related to the evaluation of enzyme activity (proprotein convertase) using electrochemical methods. In this study we used impedance spectroscopy to investigate the immobilization of peptide substrate (Arg-Val-Arg-Arg) modified with 11-mercaptoundecanoic acid on the surface of gold electrode. Both the synthesis of the peptide substrate as well as the full electrochemical characteristics of the obtained electrode materials have been described. Experimental conditions, including concentration of peptide substrate immobilization, modification time, linker, and the presence of additional blocking groups have been optimized. The main advantages of the described method is that it makes it possible to observe the peptide substrate–enzyme interaction without the need to use fluorescent labels. This also allows observation of this interaction at a very low concentration. Both of these factors make this new technique competitive with the standard spectrofluorimetric method.

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