Simulation of the magnetic nanoparticle filling procedure of microchambers

2018 ◽  
Author(s):  
Peter Palovics ◽  
Marta Rencz
Keyword(s):  
Magnetic Nanoparticle

scholarly journals Rapid hot-injection as a tool for control of magnetic nanoparticle size and morphology

RSC Advances ◽  
2021 ◽  
Vol 11 (34) ◽  
pp. 20708-20719
Author(s):  
Magdalena Kulpa-Greszta ◽  
Anna Tomaszewska ◽  
Andrzej Dziedzic ◽  
Robert Pązik
Keyword(s):  
Particle Shape ◽  
Magnetic Nanoparticle ◽  
Magnetic Particle ◽  
Nanoparticle Size ◽  
Precise Control ◽  
Hot Injection ◽  
Size And Morphology

Rapid hot-injection can be used for precise control of magnetic particle shape.

scholarly journals Understanding intracellular nanoparticle trafficking fates through spatiotemporally resolved magnetic nanoparticle recovery

2021 ◽  
Author(s):  
Emily Sheridan ◽  
Silvia Vercellino ◽  
Lorenzo Cursi ◽  
Laurent Adumeau ◽  
James A. Behan ◽  
...  
Keyword(s):  
Decision Making ◽  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Magnetic Extraction

We describe how magnetic nanoparticles can be used to study intracellular nanoparticle trafficking, and how magnetic extraction may be integrated with downstream analyses to investigate nanoscale decision-making events.

scholarly journals Therapeutic Potential of Magnetic Nanoparticle-Based Human Adipose-Derived Stem Cells in a Mouse Model of Parkinson’s Disease

2021 ◽  
Vol 22 (2) ◽  
pp. 654
Author(s):  
Ka Young Kim ◽  
Keun-A Chang
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Magnetic Nanoparticles ◽  
Substantia Nigra ◽  
Mouse Model ◽  
Magnetic Nanoparticle ◽  
Imaging System ◽  
Therapeutic Potential ◽  
Adipose Derived Stem Cells

Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra. Several treatments for PD have focused on the management of physical symptoms using dopaminergic agents. However, these treatments induce various adverse effects, including hallucinations and cognitive impairment, owing to non-targeted brain delivery, while alleviating motor symptoms. Furthermore, these therapies are not considered ultimate cures owing to limited brain self-repair and regeneration abilities. In the present study, we aimed to investigate the therapeutic potential of human adipose-derived stem cells (hASCs) using magnetic nanoparticles in a 6-hydroxydopamine (6-OHDA)-induced PD mouse model. We used the Maestro imaging system and magnetic resonance imaging (MRI) for in vivo tracking after transplantation of magnetic nanoparticle-loaded hASCs to the PD mouse model. The Maestro imaging system revealed strong hASCs signals in the brains of PD model mice. In particular, MRI revealed hASCs distribution in the substantia nigra of hASCs-injected PD mice. Behavioral evaluations, including apomorphine-induced rotation and rotarod performance, were significantly recovered in hASCs-injected 6-OHDA induced PD mice when compared with saline-treated counterparts. Herein, we investigated whether hASCs transplantation using magnetic nanoparticles recovered motor functions through targeted brain distribution in a 6-OHDA induced PD mice. These results indicate that magnetic nanoparticle-based hASCs transplantation could be a potential therapeutic strategy in PD.

scholarly journals A Dual Targeting Magnetic Nanoparticle for Human Cancer Detection

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Siwen Wu ◽  
Xiyu Liu ◽  
Jian He ◽  
Huiling Wang ◽  
Yiqun Luo ◽  
...  
Keyword(s):  
Cancer Detection ◽  
Magnetic Nanoparticle ◽  
Human Cancer ◽  
Dual Targeting
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