Generating On-Chip Heterogeneous Systems from High-Level Parallel Code

Author(s):  
Alessandro Cilardo ◽  
Luca Gallo
Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1113
Author(s):  
Mohammed Asadullah Khan ◽  
Jürgen Kosel

An integrated polymer-based magnetohydrodynamic (MHD) pump that can actuate saline fluids in closed-channel devices is presented. MHD pumps are attractive for lab-on-chip applications, due to their ability to provide high propulsive force without any moving parts. Unlike other MHD devices, a high level of integration is demonstrated by incorporating both laser-induced graphene (LIG) electrodes as well as a NdFeB magnetic-flux source in the NdFeB-polydimethylsiloxane permanent magnetic composite substrate. The effects of transferring the LIG film from polyimide to the magnetic composite substrate were studied. Operation of the integrated magneto hydrodynamic pump without disruptive bubbles was achieved. In the studied case, the pump produces a flow rate of 28.1 µL/min. while consuming ~1 mW power.


Author(s):  
Blanca Alicia Correa ◽  
Juan Fernando Eusse ◽  
Danny Munera ◽  
Jose Edinson Aedo ◽  
Juan Fernando Velez

2018 ◽  
Vol 17 (2) ◽  
pp. 393-415 ◽  
Author(s):  
Stefania Perri ◽  
Fabio Frustaci ◽  
Fanny Spagnolo ◽  
Pasquale Corsonello

Sensors ◽  
2018 ◽  
Vol 18 (9) ◽  
pp. 3016 ◽  
Author(s):  
Yeşeren Saylan ◽  
Adil Denizli

Hemoglobin is an iron carrying protein in erythrocytes and also an essential element to transfer oxygen from the lungs to the tissues. Abnormalities in hemoglobin concentration are closely correlated with health status and many diseases, including thalassemia, anemia, leukemia, heart disease, and excessive loss of blood. Particularly in resource-constrained settings existing blood analyzers are not readily applicable due to the need for high-level instrumentation and skilled personnel, thereby inexpensive, easy-to-use, and reliable detection methods are needed. Herein, a molecular fingerprints of hemoglobin on a nanofilm chip was obtained for real-time, sensitive, and selective hemoglobin detection using a surface plasmon resonance system. Briefly, through the photopolymerization technique, a template (hemoglobin) was imprinted on a monomeric (acrylamide) nanofilm on-chip using a cross-linker (methylenebisacrylamide) and an initiator-activator pair (ammonium persulfate-tetramethylethylenediamine). The molecularly imprinted nanofilm on-chip was characterized by atomic force microscopy and ellipsometry, followed by benchmarking detection performance of hemoglobin concentrations from 0.0005 mg mL−1 to 1.0 mg mL−1. Theoretical calculations and real-time detection implied that the molecularly imprinted nanofilm on-chip was able to detect as little as 0.00035 mg mL−1 of hemoglobin. In addition, the experimental results of hemoglobin detection on the chip well-fitted with the Langmuir adsorption isotherm model with high correlation coefficient (0.99) and association and dissociation coefficients (39.1 mL mg−1 and 0.03 mg mL−1) suggesting a monolayer binding characteristic. Assessments on selectivity, reusability and storage stability indicated that the presented chip is an alternative approach to current hemoglobin-targeted assays in low-resource regions, as well as antibody-based detection procedures in the field. In the future, this molecularly imprinted nanofilm on-chip can easily be integrated with portable plasmonic detectors, improving its access to these regions, as well as it can be tailored to detect other proteins and biomarkers.


2021 ◽  
Vol 26 (2) ◽  
pp. 172-183
Author(s):  
E.S. Yanakova ◽  
◽  
G.T. Macharadze ◽  
L.G. Gagarina ◽  
A.A. Shvachko ◽  
...  

A turn from homogeneous to heterogeneous architectures permits to achieve the advantages of the efficiency, size, weight and power consumption, which is especially important for the built-in solutions. However, the development of the parallel software for heterogeneous computer systems is rather complex task due to the requirements of high efficiency, easy programming and the process of scaling. In the paper the efficiency of parallel-pipelined processing of video information in multiprocessor heterogeneous systems on a chip (SoC) such as DSP, GPU, ISP, VDP, VPU and others, has been investigated. A typical scheme of parallel-pipelined processing of video data using various accelerators has been presented. The scheme of the parallel-pipelined video data on heterogeneous SoC 1892VM248 has been developed. The methods of efficient parallel-pipelined processing of video data in heterogeneous computers (SoC), consisting of the operating system level, programming technologies level and the application level, have been proposed. A comparative analysis of the most common programming technologies, such as OpenCL, OpenMP, MPI, OpenAMP, has been performed. The analysis has shown that depend-ing on the device finite purpose two programming paradigms should be applied: based on OpenCL technology (for built-in system) and MPI technology (for inter-cell and inter processor interaction). The results obtained of the parallel-pipelined processing within the framework of the face recognition have confirmed the effectiveness of the chosen solutions.


Author(s):  
Reinaldo Lucas dos Santos Rosa ◽  
Antonio Carlos Seabra

This chapter provides a guide for microfluidic devices development and optimization focused on chemical analysis applications, which includes medicine, biology, chemistry, and environmental monitoring, showing high-level performance associated with a specific functionality. Examples are chemical analysis, solid phase extraction, chromatography, immunoassay analysis, protein and DNA separation, cell sorting and manipulation, cellular biology, and mass spectrometry. In this chapter, most information is related to microfluidic devices design and fabrication used to perform several steps concerning chemical analysis, process preparation of reagents, samples reaction and detection, regarding water quality monitoring. These steps are especially relevant to lab-on-chip (LOC) and micro-total-analysis-systems (μTAS). μTAS devices are developed in order to simplify analytical chemist work, incorporating several analytical procedures into flow systems. In the case of miniaturized devices, the analysis time is reduced, and small volumes (nL) can be used.


Electronics ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 292
Author(s):  
Stefania Perri ◽  
Fanny Spagnolo ◽  
Pasquale Corsonello

Connected component labeling is one of the most important processes for image analysis, image understanding, pattern recognition, and computer vision. It performs inherently sequential operations to scan a binary input image and to assign a unique label to all pixels of each object. This paper presents a novel hardware-oriented labeling approach able to process input pixels in parallel, thus speeding up the labeling task with respect to state-of-the-art competitors. For purposes of comparison with existing designs, several hardware implementations are characterized for different image sizes and realization platforms. The obtained results demonstrate that frame rates and resource efficiency significantly higher than existing counterparts are achieved. The proposed hardware architecture is purposely designed to comply with the fourth generation of the advanced extensible interface (AXI4) protocol and to store intermediate and final outputs within an off-chip memory. Therefore, it can be directly integrated as a custom accelerator in virtually any modern heterogeneous embedded system-on-chip (SoC). As an example, when integrated within the Xilinx Zynq-7000 X C7Z020 SoC, the novel design processes more than 1.9 pixels per clock cycle, thus furnishing more than 30 2k × 2k labeled frames per second by using 3688 Look-Up Tables (LUTs), 1415 Flip Flops (FFs), and 10 kb of on-chip memory.


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